1.Screening Colonoscopy among Uninsured and Underinsured Urban Minorities.
Tyson H COLLAZO ; Lina JANDORF ; Linda THELEMAQUE ; Kristen LEE ; Steven H ITZKOWITZ
Gut and Liver 2015;9(4):502-508
BACKGROUND/AIMS: Uninsured individuals have lower rates of screening colonoscopy (SC), and little is known regarding the pathology results obtained when they undergo colonoscopies. Since 2004, we have participated in a program that offers SC to uninsured New Yorkers; herein, we report our findings. METHODS: Uninsured, average-risk patients who were at least 50 years of age underwent SC at our institution between April 2004 and June 2011. We analyzed polyp pathology, location, size, incidence of adenomas, and incidence of adenomas with advanced pathology (AAP) with respect to ethnicity, gender, and age. RESULTS: Out of 493 referrals, 222 patients completed the colonoscopies. Polyps were identified in 21.2% of all patients; 14% had adenomas, and 4.5% had AAP. The rates of adenomas among African-Americans, Hispanics, and Whites were 24.3%, 12.1%, and 11.6%, respectively, and the corresponding rates of AAP were 10.8%, 3.5%, and 2.3%. Differences in the polyp type, location, and AAP did not reach statistical significance with respect to ethnicity or gender. Patients aged 60 and older were found to have a higher rate of advanced adenomas compared with younger patients (8.6% vs 2.6%, p=0.047). CONCLUSIONS: Further efforts to fund screening colonoscopies for uninsured individuals will likely result in the identification of advanced lesions of the colon before they progress to colorectal cancer.
Adenoma/diagnosis/epidemiology
;
African Americans/statistics & numerical data
;
Age Factors
;
Aged
;
Colon/pathology
;
Colonic Neoplasms/diagnosis/epidemiology
;
Colonic Polyps/diagnosis/epidemiology
;
Colonoscopy/*statistics & numerical data
;
European Continental Ancestry Group/statistics & numerical data
;
Female
;
Hispanic Americans/statistics & numerical data
;
Humans
;
Incidence
;
Male
;
Mass Screening/*statistics & numerical data
;
Medically Uninsured/*statistics & numerical data
;
Middle Aged
;
Minority Groups/*statistics & numerical data
;
New York City/epidemiology
;
Program Evaluation
;
*Urban Population
2.The impact of combined radiation and chemotherapy on outcome in uterine papillary serous carcinoma compared to chemotherapy alone.
Haider MAHDI ; Benjamin NUTTER ; Fadi ABDUL-KARIM ; Sudha AMARNATH ; Peter G ROSE
Journal of Gynecologic Oncology 2016;27(2):e19-
OBJECTIVE: To investigate the impact of pelvic radiation on survival in patients with uterine serous carcinoma (USC) who received adjuvant chemotherapy. METHODS: Patients with stage I-IV USC were identified from the Surveillance, Epidemiology, and End Results program 2000 to 2009. Patients were included if treated with surgery and chemotherapy. Patients were divided into two groups: those who received chemotherapy and pelvic radiation therapy (CT_RT) and those who received chemotherapy only (CT). Kaplan-Meier curves and Cox regression proportional hazard models were used. RESULTS: Of the 1,838 included patients, 1,272 (69%) were CT and 566 (31%) were CT_RT. Adjuvant radiation was associated with significant improvement in overall survival (OS; p<0.001) and disease-specific survival (DSS; p<0.001) for entire cohort. These findings were consistent for the impact of radiation on OS (p<0.001) and DSS (p<0.001) in advanced stage (III-IV) disease but not for early stage (I-II) disease (p=0.21 for OS and p=0.82 for DSS). In multivariable analysis adjusting for age, stage, race and extent of lymphadenectomy, adjuvant radiation was a significant predictor of OS and DSS for entire cohort (p=0.003 and p=0.05) and in subset of patients with stage III (p=0.02 and p=0.07) but not for patients with stage I (p=0.59 and p=0.49), II (p=0.83 and p=0.82), and IV USC (p=0.50 and p=0.96). Other predictors were stage, positive cytology, African American race and extent of lymphadenectomy. CONCLUSION: In USC patients who received adjuvant chemotherapy, adjuvant radiation was associated with significantly improved outcome in stage III disease but not for other stages. Positive cytology, extent of lymphadenectomy and African race were significant predictors of outcome.
Adult
;
African Americans/statistics & numerical data
;
Aged
;
Aged, 80 and over
;
Carcinoma, Papillary/pathology/radiotherapy/*therapy
;
Chemoradiotherapy, Adjuvant
;
Chemotherapy, Adjuvant
;
Female
;
Humans
;
Hysterectomy
;
*Lymph Node Excision
;
Middle Aged
;
Neoplasm Staging
;
SEER Program
;
Survival Rate
;
Uterine Neoplasms/pathology/radiotherapy/*therapy
3.Morphologic Variability of the Shoulder between the Populations of North American and East Asian.
Andres F CABEZAS ; Kristi KREBES ; Michael M HUSSEY ; Brandon G SANTONI ; Hyuong Sik KIM ; Mark A FRANKLE ; Joo Han OH
Clinics in Orthopedic Surgery 2016;8(3):280-287
BACKGROUND: The aim of this study was to determine if there were significant differences in glenohumeral joint morphology between North American and East Asian populations that may influence sizing and selection of shoulder arthroplasty systems. METHODS: Computed tomography reconstructions of 92 North American and 58 East Asian patients were used to perform 3-dimensional measurements. The proximal humeral position was normalized in all patients by aligning it with the scapular plane utilizing anatomic landmarks. Measurements were performed on the humerus and scapula and included coronal and axial humeral head radius, humeral neck shaft and articular arc angles, glenoid height and width, and critical shoulder angle. Glenohumeral relationships were also measured and included lateral distance to the greater tuberosity and acromion, abduction lever arm, and acromial index. Parametric and nonparametric statistical analyses were used to compare population metrics. RESULTS: East Asian glenohumeral measurements were significantly smaller for all linear metrics (p < 0.05), with the exception of acromial length, which was greater than in the North American cohort (p < 0.001). The increase in acromial length affected all measurements involving the acromion including abduction lever arms. No difference was found between the neck shaft and articular angular measurements. CONCLUSIONS: The East Asian population exhibited smaller shoulder morphometrics than their North American cohort, with the exception of an extended acromial overhang. The morphologic data can provide some additional factors to consider when choosing an optimal shoulder implant for the East Asian population, in addition to creating future designs that may better accommodate this population.
African Americans/*statistics & numerical data
;
Aged
;
Anthropometry
;
Asian Continental Ancestry Group/*statistics & numerical data
;
European Continental Ancestry Group/*statistics & numerical data
;
Female
;
Humans
;
Male
;
Prosthesis Design
;
Republic of Korea/epidemiology
;
Shoulder/*anatomy & histology
;
Shoulder Joint/*anatomy & histology
;
Shoulder Prosthesis
;
United States/epidemiology