1.Erratum: Correction of Prevalence of Falls by Sex in Article 'Risk Factors for Falls in Older Korean Adults: The 2011 Community Health Survey'.
Eun Jin CHOI ; Sun A KIM ; Nu Ri KIM ; Jung Ae RHEE ; Yong Woon YUN ; Min Ho SHIN
Journal of Korean Medical Science 2015;30(1):117-117
We made a mistake in our recently published article.
2.Imprint Cytology of Soft Tissue Myoepithelioma: A Case Study.
Seok Ju PARK ; Ae Ri KIM ; Mi Jin GU ; Joon Hyuk CHOI ; Duk Seop SHIN
Korean Journal of Pathology 2013;47(3):299-303
Soft tissue myoepithelioma is a rare neoplasm composed of myoepithelial cells. Here, we describe the cytologic features of soft tissue myoepithelioma arising on the right forearm in an 18-year-old man. The excised tumor (3.0x1.8x1.5 cm) was well-demarcated, yellow-gray, soft, and myxoid. The cytologic smears showed round to spindle, epithelioid, and plasmacytoid cells in the myxoid background. The nuclei were uniform, round to ovoid, with finely distributed chromatin and eosinophilic or pale cytoplasm. The tumor cells demonstrated immunoreactivity for cytokeratin (AE1/AE3), epithelial membrane antigen, S100 protein, and glial fibrillary acidic protein. Electron microscopy showed intermediate filaments, desmosomes, and basal lamina.
Basement Membrane
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Chromatin
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Cytoplasm
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Desmosomes
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Eosinophils
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Forearm
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Glial Fibrillary Acidic Protein
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Intermediate Filaments
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Keratins
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Microscopy, Electron
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Mucin-1
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Myoepithelioma
3.Effects of Folic Acid or Ascorbate Supplementation on Plasma Homocysteine Levels and Oxidative Stress in Korean Adults with Impaired Fasting Glucose.
Mir Ri HWANG ; Min Ho SHIN ; Jung Ae RHEE ; Sun Seog KWEON ; Hyeon Sook LIM
Korean Journal of Community Nutrition 2008;13(2):263-275
Impaired fasting glucose (IFG) is one of significant risk factors of developing diabetes. The persons with IFG are, thus, an important target group for primary prevention of diabetes. It is well known that plasma homocysteine concentration may be increased in poor folate nutritional status. Elevated level of plasma homocysteine is considered as a marker of enhanced oxidative stress. In addition, the protective effect against oxidative stress may be diminished in poor antioxidative nutrient status as vitamin C. It is, therefore, important to maintain adequate nutritional status of folate and vitamin C in the patients with type 2 diabetes or IFG. This study was performed to determine the effects of supplementation of folic acid or vitamin C on plasma concentrations of homocysteine, oxidized LDL, and lipids and on the activity of plasma anti-oxidative enzyme in patients with IFG. A total of 97 patients with IFG were participated voluntarily with written consents. They were divided into one of the four experimental groups; Control (C), Folatesupplemented (F), Ascorbate-supplemented (A), and Folate plus ascorbate-supplemented (FA). The subjects in C were taken placebo, those in F were supplemented 1 mg of folate, those in A were received 1,000 mg of vitamin C, and those in FA were given 1 mg of folate plus 1,000 mg of vitamin C daily for 4 weeks. No change in plasma concentrations of vitamin C, lipids, and oxidized LDL and the activity of GSH-Px were observed in vitamin C-supplemented group (A + FA) and folate-supplemented group (F + FA) compared to the placebo group (C + A). Only the folate-supplemented group (F + FA) had significantly increased average serum folate concentration and lowered plasma homocysteine concentration compared to the placebo group (C + A). Thus, it should be recommended the patients with IFG to increase folate intake through diets and, if it is not sufficient, to take folic acid supplements to prevent the development of complications induced by hyperhomocysteinemia as well as oxidative stress.
Adult
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Ascorbic Acid
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Diet
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Fasting
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Folic Acid
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Glucose
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Homocysteine
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Humans
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Hyperhomocysteinemia
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Lipoproteins, LDL
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Nutritional Status
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Oxidative Stress
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Plasma
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Primary Prevention
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Risk Factors
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Vitamins
4.Identification and partial purification of antibacterial compounds against Streptococcus mutans from Galla Rhois.
Ae Ri SHIN ; Seung Ho OHK ; Choong Ho CHOI ; Suk Jin HONG
Journal of Korean Academy of Oral Health 2016;40(1):3-8
OBJECTIVES: This study aims to identify and partially purify antibacterial compounds against Streptococcus mutans from Galla Rhois extract. METHODS: Galla Rhois was extracted with n-hexane or ethanol and concentrated in a rotary evaporator. The antibacterial effect of the Galla Rhois extract against S. mutans was determined by the paper discdiffusion method with n-hexane, ethanol, methanol, ethyl acetate, dimethyl sulfoxide (DMSO), acetone, and distilled water as the solvents. The active compounds were purified by partition chromatography, thin-layer chromatography (TLC), and high-performance liquid chromatography (HPLC). RESULTS: The antibacterial effect of the n-hexane extract was more effective against S. mutans than the ethanol extract (P<0.05). The antibacterial component of Galla Rhois was partially purified using partition chromatography and HPLC, and the antibacterial activity was confirmed. CONCLUSIONS: The partially purified component of Galla Rhois showed strong antibacterial effect against S. mutans. These results confirm that the antibacterial compounds of Galla Rhois can be used for the prevention of dental caries.
Acetone
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Chromatography
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Chromatography, High Pressure Liquid
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Chromatography, Liquid
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Chromatography, Thin Layer
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Dental Caries
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Dimethyl Sulfoxide
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Ethanol
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Methanol
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Solvents
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Streptococcus mutans*
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Streptococcus*
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Water
5.Growth inhibition effect of Rubus coreanus Miquel on Candida albicans.
Ae Ri SHIN ; Seung Ho OHK ; Choong Ho CHOI ; Suk Jin HONG
Journal of Korean Academy of Oral Health 2015;39(3):168-173
OBJECTIVES: In this study, the growth inhibition effect of Rubus coreanus Miquel on Candida albicans (C. albicans) was observed. METHODS: The Rubus coreanus Miquel was extracted with 70% methanol and concentrated with a rotary evaporator. Antifungal effect of Rubus coreanus Miquel extract on C. albicans was determined by paper disc diffusion method and standard plate count method. Seven different concentrations (2, 4, 8, 15, 30, 60, 120 mg/ml) of the extract were tested by paper disc diffusion method. Two kinds of concentration (8, 60 mg/ml) of the extract were tested using standard plate count method on C. albicans with different incubating time (for 6, 12, 24 hours immediately after the cultivation). Morphological changes of C. albicans cells after exposure to the extract were observed with scanning electron microscopy (SEM) images. RESULTS: The Rubus coreanus Miquel extract showed an antifungal effect on C. albicans in 8, 15, 30, 60, 120 mg/ml of concentrations (P<0.05). The extract with 8 mg/ml of concentration showed about 30% of growth inhibition at 6 h and with 60 mg/ml it showed about 90% of growth inhibition at 24 h. SEM analysis showed damaged surfaces of C. albicans cells when treated with Rubus coreanus Miquel extract. CONCLUSIONS: The Rubus coreanus Miquel might have the potential as a nobel growth inhibitory agent against C. albicans that causes oral infection.
Candida albicans*
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Candida*
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Diffusion
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Methanol
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Microscopy, Electron, Scanning
6.Validation of the Korean version of the StandardizedCosmesis and Health Nasal Outcomes Survey
Woo Ri CHOI ; Shin Ae KIM ; Sung Hee KIM ; Yong Ju JANG
Korean Journal of Otolaryngology - Head and Neck Surgery 2020;63(4):163-166
Background and Objectives:
The 10-item Standardized Cosmesis and Health Nasal Outcomes Survey (SCHNOS) is a recently developed questionnaire for assessing both nasal obstruction and nasal cosmetic satisfaction. It is widely used in rhinoplasty clinics based on its high level of reliability and efficacy in Western countries. In this study we evaluated the validity of the Korean version of the SCHNOS (K-SCHNOS).Subjects and Method The SCHNOS was translated into easily-understandable Korean following the guideline of the developers. Twenty-seven patients undergoing rhinoplasty and a control group of 29 non-rhinoplasty patients completed K-SCHNOS twice at intervals of 2 weeks regardless of pre- or postoperative state. The K-SCHNOS was evaluated for internal consistency, test-retest reliability, and validity.
Results:
Of the 56 study participants, 39 (69.6%) were male and 17 (30.4%) were female, with the mean (standard deviation) age of 33.5 (12.9) years. Both obstructive domain and cosmetic domains showed high internal consistency with their respective Cronbach’α values being 0.92 and 0.91. The correlations in the test-retest analysis for each item were acceptable, ranging from 0.6-0.82. The association between the obstructive domain and cosmetic domain was 0.48 (95% confidence interval, 0.32-0.61), indicating a very weak correlation.
Conclusion
The K-SCHNOS has proven to be a reliable and valid questionnaire to be used by Korean-speaking patients undergoing functional or cosmetic rhinoplasty.
7.Risk Factors for Falls in Older Korean Adults: The 2011 Community Health Survey.
Eun Jin CHOI ; Sun A KIM ; Nu Ri KIM ; Jung Ae RHEE ; Yong Woon YUN ; Min Ho SHIN
Journal of Korean Medical Science 2014;29(11):1482-1487
Falls are a major health problem for elderly populations worldwide. We analyzed data from the 2011 Korean Community Health Survey to identify potential risk factors for falls in a representative population-based sample of community-dwelling older Korean adults. Risk factors for falls were assessed by multivariate survey logistic regression models. The prevalence of falls was 36.5% in males and 63.5% in females. Age and female sex were associated with a higher risk of falls. Similarly, living alone, living in an urban area, poor self-rated health, and high stress were associated with a high risk of falls. Subjects with diabetes mellitus, stroke, osteoarthritis, osteoporosis, urinary incontinence, cataracts, or depression had a high risk of falls. However, subjects with hypertension were at low risk for falls. In conclusion, age, female sex, marital status, residence location, self-rated health, stress, and several chronic conditions were significantly associated with the risk for falls in the older Korean adults. Our findings suggest that these risk factors should be addressed in public health policies for preventing falls.
Accidental Falls/*statistics & numerical data
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Age Factors
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Aged
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Aged, 80 and over
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Data Collection
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Female
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Health Surveys
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Humans
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Logistic Models
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Male
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Marital Status
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Odds Ratio
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Republic of Korea
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Residence Characteristics
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Risk Factors
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Severity of Illness Index
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Sex Factors
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Stress, Psychological
8.Effects of School-Based Social Skills Training Program on Alexithymic Tendency: Preliminary Study.
Min Soo KIM ; Jung Uk SHIN ; Young Ryeol LEE ; Yeon Woo LEE ; Kyung Ae JUNG ; Dool Nam JUNG ; Mi Ri PARK ; Gang Sik SONG ; Sang Soo SEO
Journal of the Korean Academy of Child and Adolescent Psychiatry 2016;27(3):216-225
OBJECTIVES: The purposes of this study are to evaluate the effect of a school-based social skills training program on the emotional regulation of children and adolescents and to assess the plan for effective school-based mental health services. METHODS: The Child and Adolescent Mental health promotion team of Bugok National Hospital conducted school-based social skills training (N=90, 7 sessions) for elementary and middle school students. Evaluations were conducted before and after the application of the program using a prosocial behavior questionnaire, a cohesiveness questionnaire, the Korean version of the 20-item Toronto Alexithymia Scale, a self-esteem scale, and the Novaco anger scale, in order to identify any changes. RESULTS: The social skills training program increased the prosocial behavior and cohesiveness of the children and adolescents and decreased their alexithymic tendency and degree of anger, but did not significantly change their self-esteem. CONCLUSION: The social skills training program positively influences the emotional and behavioral levels of children and adolescents. The emotional regulation program based on a social skills training program is expected to have positive results in school-based mental health services. Future investigations are needed to validate the long term effects of this program.
Adolescent
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Affective Symptoms
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Anger
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Child
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Education*
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Humans
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Mental Health
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Mental Health Services
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Social Skills*
9.Ectopic Male Breast Cancer in Suprapubic Area That Relapsed with Hematogenous Metastasis
Jung Hee BYON ; Ae Ri AN ; Jin Yong SHIN ; Eun Jung CHOI
Journal of Breast Cancer 2021;24(3):344-348
Tough ectopic male breast cancer is extremely rare, non-axillary ectopic male breast cancer is even rare. To date, the natural course and prognosis of this disease are not fully understood.Consequently, the appropriate treatment for this disease has not been established. We report on a patient with ectopic male breast cancer in the suprapubic area that relapsed with hematogenous metastasis 3 years after complete surgical resection and adjuvant treatment despite an early diagnosis. This unusual case highlights the need for new prognostic factors such as genomic profiling to predict whether ectopic male breast cancer is aggressive and to guide on the duration between follow-ups and the appropriate method for conducting them.
10.Ectopic Male Breast Cancer in Suprapubic Area That Relapsed with Hematogenous Metastasis
Jung Hee BYON ; Ae Ri AN ; Jin Yong SHIN ; Eun Jung CHOI
Journal of Breast Cancer 2021;24(3):344-348
Tough ectopic male breast cancer is extremely rare, non-axillary ectopic male breast cancer is even rare. To date, the natural course and prognosis of this disease are not fully understood.Consequently, the appropriate treatment for this disease has not been established. We report on a patient with ectopic male breast cancer in the suprapubic area that relapsed with hematogenous metastasis 3 years after complete surgical resection and adjuvant treatment despite an early diagnosis. This unusual case highlights the need for new prognostic factors such as genomic profiling to predict whether ectopic male breast cancer is aggressive and to guide on the duration between follow-ups and the appropriate method for conducting them.