1.Brain MRI Findings of the Cri-Du-Chat Syndrome: A Case Report and Summary
Jin Sol CHOI ; Eun Ae YOO ; Jin Ok CHOI ; Soo Jung KIM
Journal of the Korean Radiological Society 2020;81(4):979-984
Cri-du-chat syndrome is a rare genetic disorder in which the patient presents with a characteristic high-pitched monotonous cry and recurrent aspiration pneumonia, attributed to abnormalities in the larynx, epiglottis, and nervous system. The most prominent brain MRI findings are the presence of pontine and cerebellar hypoplasia, which primarily involve posterior cranial fossa structures. Although atrophy of supratentorial structures were also a common radiological finding, it was considered to be a secondary change due to pontine hypoplasia. Here, we present the case of a three-month-old patient presenting with cri-du-chat at our institution. The patient also showed the presence of prominent pontine hypoplasia similar to previously reported cases; however, contrary to other cases, there was a general delayed myelination of brain instead of decreased myelination of anterior limb of internal capsule. Since the larynx, pons, and cerebellum all originated from similar notochord level, which suggests anomaly in early stage of development, laryngeal, and brain anomaly characteristically observed in the cridu- chat syndrome.
2.Delayed Post-Hypoxic Leukoencephalopathy Induced by an Overdose with Fentanyl Patches: A Case Report
Jin Sol CHOI ; Eun Ae YOO ; Jin Ok CHOI ; Soo Jung KIM
Journal of the Korean Radiological Society 2020;81(4):972-978
Fentanyl intoxication has occasionally been reported since fentanyl patches became available for medical use. Delayed post-hypoxic leukoencephalopathy is a complication of hypoxia. However, its neuropsychiatric symptoms can be delayed, and it can progress to leukoencephalopathy even after full recovery from coma due to acute intoxication. Herein, we report a case of fentanyl intoxication in a 65-year-old man who was presented to the hospital because of unconsciousness for 13 hours after using ten fentanyl patches simultaneously. Initial brain CT findings were non-specific. Twenty days later, delayed neuropathologic symptoms manifested, and MRI showed bilaterally symmetrical, heterogeneous, confluent high signal intensities on T2-weighted/fluid attenuated inversion recovery MRI in the cerebral white matter with diffusion restriction. This was followed by rapid exacerbation of neuropathological symptoms with diffuse severe cerebral atrophy over 1 year.
3.Two Cases of Partial Unilateral Lentiginosis.
Kyung Jin KIM ; In Ae CHUNG ; Youn Hong CHOI ; Byoung Soo CHUNG
Korean Journal of Dermatology 1987;25(2):264-268
Partial unilateral lentiginosis(PUL) is a rare pigmentary disorder charaeterized by lentigines limited to one side of the body with or without neurologic abnormalities. We report two cases of PUL unassociated with any other defect, One patient was 20-year-old female who had lentigines confined to the right side of the face and the other was 19-year-old male who had lentigines confined to the left side of the neck and upper trunk and left upper extremity. Histologic examination of the pigmented lesion revealed findings consistent with lentigo simplex.
Female
;
Humans
;
Lentigo*
;
Male
;
Neck
;
Upper Extremity
;
Young Adult
4.Fever Phobia: A Survey of Children's Parents in a Pediatric Outpatient Clinic.
Child Health Nursing Research 2014;20(2):113-122
PURPOSE: Purposes of this study were to identify the level of parental fever phobia and to investigate the relationship between level of parental concern about fever and related variables. METHODS: Participants were 151 parents of children who visited a pediatric outpatient clinic. A self-reported structured questionnaire was used for data collection and data were analyzed using descriptive statistics and chi2-test. RESULTS: Almost half of participants defined a minimum temperature for fever as 37.8degrees C and a minimum temperature for high fever as 38.9degrees C. About 75% of participants identified harmful effects of fever as seizure and brain damage, were 'very worried' about fever, measured their child's temperature every hour or less, provided tepid massage and woke children to give antipyretics during febrile illness. There were significant relationships between level of parental concerns about fever and prior experience of febrile seizures, and/or being parents of a single child. CONCLUSION: Results indicate that fever phobia is prevalent among parents. Further studies are needed to develop and evaluate childhood fever management educational programs for parents. Considering health care providers as a primary information resource about fever management, health care providers should play a vital role to reduce parental unrealistic concerns about fever.
Ambulatory Care Facilities*
;
Antipyretics
;
Brain
;
Child
;
Data Collection
;
Fever*
;
Health Personnel
;
Humans
;
Massage
;
Parents*
;
Phobic Disorders*
;
Seizures
;
Seizures, Febrile
;
Surveys and Questionnaires
5.Sebaceous Carcinoma and Basal Cell Epithelioma Developed in Organoid Nevus.
Kyoung Ae JANG ; Seh Jin AHN ; Jee Ho CHOI ; Jai Kyoung KOH
Annals of Dermatology 1999;11(1):59-61
In about 20 to 30 percent of cases with organoid nevus (nevus sebaceus), benign and/or ma-al lignant tumors of the epidermis and adnexae may develop. We describe a 71-year-old woman with sebaceous carcinoma and basal cell epithelioma developed in organoid nevus.
Aged
;
Carcinoma, Basal Cell*
;
Epidermis
;
Female
;
Humans
;
Nevus*
;
Organoids*
6.Seroma of the Auricle.
Kyung Jin KIM ; In Ae CHUNG ; Byoung Soo CHUNG ; Kyu Cherl CHOI
Korean Journal of Dermatology 1987;25(1):135-137
A 35-year-old female patient had a cyst-Jike swelling for one month on the right scaphoid fossa and antihelix of the auricle. Histopathologically, cystic cavity was located in lower dermis and cavity roof was composed of fibrous material without cartilagenous structure. Treatrment consisted of incision and drainage and subsequently rnastoidectomy dressing for one week. One month after treatment, recurrence of lesion was not found.
Adult
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Bandages
;
Dermis
;
Drainage
;
Female
;
Humans
;
Recurrence
;
Seroma*
7.Community screening for stress by using General Health Questionnaire.
Soo Sung OH ; Kwang Seub LEE ; Seok Joon SOHN ; Jin Su CHOI ; Jung Ae RHEE
Korean Journal of Preventive Medicine 1995;28(1):123-140
This study investigated the stress of community residents in Kwang-Ju and Chonnam areas by using the General Health Questionnaire(GHQ-60) as a instrument of stress measurement. The number of subject were 445 residents who lived in three areas (large city, middle city, and rural area) and they were individually interviewed in March, 1994. The result of study showed that the degrees of stress measured by GHQ-60 were statistically significant in the residents' area, age. sex variables: (a) the residents in middle city among three area had the highest level of stress: (b) the resident who were more than 60 in age had the highest level of stress: (c) the female resident had more stress than male residents: (d) particularly, the residents who were more than 60 years old in the middle city had the highest level of stress. Further, the results of factor analysis showed that there were three factors of social dysfunction, depression and anxiety, and psychosomatic symptom. The social dysfunction factor was statistically significant in both age and resident area variables. The depression and anxiety factor was statistically significant in the residents' area, age. sex variables. The psychosomatic symptom factor was statistically significant in both age and sex variables. The study suggested that they should give a special attention to solve the old people's stress because stress was closely related to residents age.
Anxiety
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Depression
;
Factor Analysis, Statistical
;
Female
;
Gwangju
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Humans
;
Jeollanam-do
;
Male
;
Mass Screening*
;
Middle Aged
;
Surveys and Questionnaires*
8.A case of Eosinophilic Ascites noted in Eosinophilic Gastroenteritis.
Ae Seek KIM ; Hak Jin KIM ; Young Hee CHOI
Korean Journal of Clinical Pathology 1999;19(2):271-274
The observation of eosinophilic ascites is uncommon. They can be noted in parasitic disease, malignant condition, vasculitis, idiopathic hypereosinophilic syndrome or allergic disorders including eosinophilic gastroenteritis, which is a rare disease of unknown etiology characterized by massive tissue infiltration of eosinophils in the layers of any area of gastrointestinal[GI] tract. Clinical manifestations are related to the level of the histologic infiltration in the wall, and the segment of the GI tract involved. Mucosal involvement may result in abdominal pain, nausea, vomiting, diarrhea and weight loss. Muscle layer involvements have obstructive symptoms. Subserosal eosinophilic infiltration may result in the development of eosinophilic ascites. We experienced a case of eosinophilic ascites as manifestation of eosinophilic gastroenteritis in a 43-year old man who also had jejunal obstruction. High proportion of eosinophil count was noted in the ascites, however peripheral blood eosinophilia was not noted. Parasitologic studies were negative. Histologic examination of segment of jejunum showed heavy transmural infiltration of eosinophils which were extended to subserosal layer. Eosinophilic ascites noted in eosinophilic gastroenteritis, though not a common disease entity, had not been described in the laboratory medicine related papers in Korea. Therefore we report this case as an example of eosinophilic ascites.
Abdominal Pain
;
Adult
;
Ascites*
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Diarrhea
;
Eosinophilia
;
Eosinophils*
;
Gastroenteritis*
;
Gastrointestinal Tract
;
Humans
;
Hypereosinophilic Syndrome
;
Jejunum
;
Korea
;
Nausea
;
Parasitic Diseases
;
Rare Diseases
;
Vasculitis
;
Vomiting
;
Weight Loss
9.Immunohistochemical assay of cathepsin-D in breast carcinomas:comparison with age tumor size, lymphnode invasiveness and estrogen receptor.
Se Hwan HAN ; Dong Young ROH ; Kook Jin CHOI ; Jin Bok KIM ; Wang Jae LEE ; In Ae PARK
Journal of the Korean Cancer Association 1993;25(5):658-663
No abstract available.
Breast*
;
Estrogens*
10.Study on Consequent Nutrient Intake Status, Body Mass Index, and Fat Distribution after Silk Amino Peptide and Dietary Fiber Supplementation..
Sung Hee LEE ; Ae Jin CHOI ; Soo Jin SONG ; Jung Min RYU
Journal of the Korean Dietetic Association 2002;8(2):175-184
This study is to investigate consequent nutrient intake status, influence of body mass index(BMI), and fat distribution on the silk amino peptide(SAP) and dietary fiber supplementation. During 2 months of this research (January to March, 2002), 45 women aged 20yr - 30yr (average age 24.6yr) were selected as subjects. Nutrient intake was investigated by questionnaire, 24-hr recall method. Antropometric assessments of the subjects were investigated by SBIA method(Segmental bioimpedance assay, In body 3.0). The results are as follows : mean body weight 57.7kg, mean body height 161.9cm mean BMI 22.0, and mean food habit score was 8.47. Defecation frequency was increased by dietary fiber supplementation. Frequency of pain during defecation was significantly decreased by dietary fiber supplementation (p<0.01). Feeling of residual feces was significantly improved by dietary fiber supplementation(p<0.001). Status of energy and carbohydrate intakes significantly decreased after dietary fiber supplementation(P<0.05). Body fat and WHR(waist hip ratio) significantly decreased after dietary fiber supplementation(P<0.001), and percent body fat was decreased by dietary fiber supplementation, significantly(P<0.05). Above results of this study show that dietary fiber-added routine diet improves defecation condition, and lessens body fat, percent body fat without losing body muscle. Especially, declination of abdominal fat and WHR were notable. That meant decreased risk factor.
Abdominal Fat
;
Adipose Tissue
;
Body Height
;
Body Mass Index*
;
Body Weight
;
Defecation
;
Diet
;
Dietary Fiber*
;
Feces
;
Female
;
Food Habits
;
Hip
;
Humans
;
Surveys and Questionnaires
;
Risk Factors
;
Silk*