1.Conn's Syndrome Associated with Behcet's Disease.
Journal of Korean Medical Science 2003;18(1):145-147
A 39-yr-old woman, who had been treated for Behcet's disease for 4 yr, was admitted for further investigation of recently identified hypokalemia and hypertension. Suppressed plasma renin activity with elevated plasma aldosterone concentration and an anomalous postural decrease in plasma aldosterone were observed. An abdominal CT scan revealed a right adrenal mass. The patient was diagnosed with Conn's syndrome. The association of Conn's syndrome with Behcet's disease was thought to be coincidental. To our knowledge, this is the first case of Conn's syndrome associated with Behcet's disease.
Adenoma/complications
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Adenoma/radiography
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Adenoma/secretion
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Adenoma/surgery
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Adrenal Cortex Neoplasms/complications
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Adrenal Cortex Neoplasms/radiography
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Adrenal Cortex Neoplasms/secretion
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Adrenal Cortex Neoplasms/surgery
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Adrenalectomy
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Adult
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Aldosterone/secretion
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Behcet Syndrome/complications*
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Female
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Human
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Hyperaldosteronism/blood
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Hyperaldosteronism/complications*
2.Aldosterone-Producing Adrenocortical Carcinoma without Hypertension.
Min Soo SONG ; Sung Woo SEO ; Sang Byung BAE ; Yeo Joo KIM ; Sang Jin KIM
The Korean Journal of Internal Medicine 2012;27(2):221-223
Although adrenocortical tumors are common, adrenocortical carcinomas are rare. Moreover, aldosterone-producing adrenocortical carcinomas without hypertension are exceedingly rare, with only two previously reported cases.
Adrenal Cortex Neoplasms/*complications/secretion/surgery
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Adrenalectomy
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Adrenocortical Carcinoma/*complications/secretion/surgery
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Adult
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Aldosterone/*secretion
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Biopsy
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Female
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Humans
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Hyperaldosteronism/*etiology
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Hypertension/etiology
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Tomography, X-Ray Computed
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Treatment Outcome
3.A Case of Cushing's Syndrome Presenting as Endometrial Hyperplasia.
Sang Min LEE ; Jong Ryeal HAHM ; Tae Sik JUNG ; Jung Hwa JUNG ; Mi Yeon KANG ; Sun Joo KIM ; Soon Il CHUNG
The Korean Journal of Internal Medicine 2008;23(1):49-52
We describe here the case of a 39-year-old woman with a cortisol-producing adrenal adenoma and she presented with endometrial hyperplasia and hypertension without the specific characteristics of Cushing's syndrome. The patient had consulted a gynecologist for menometrorrhagia 2 years prior to her referral and she was diagnosed with endometrial hyperplasia and hypertension. Her blood pressure and the endometrial lesion were refractory despite taking multiple antihypertensives and repetitive dilation and curettage and progestin treatment. On admission, the clinical examination revealed mild central obesity (a body mass index of 22.9 kg/m2, a waist circumference of 85 cm and a hip circumference of 94cm), but there was no hirsutism and myopathy. She showed impaired glucose tolerance on an oral glucose tolerance test. The biochemical hypercortisolemia together with the prolactin and androgen levels were evaluated to explore the cause of her anovulation. Adrenal Cushing's syndrome was confirmed on the basis of the elevated urinary free cortisol (454 microgram/24h, normal range: 20-70) with a suppressed ACTH level (2.0 pg/mL, normal range: 6.0-76.0) and the loss of circadian cortisol secretion. A CT scan revealed a 3.1 cm, hyperechoic, well-marginated mass in the left adrenal gland. Ten months post-adrenalectomy, the patient had unintentionally lost 9 kg of body weight, had regained a regular menstrual cycle and had normal thickness of her endometrium.
Adrenal Cortex Neoplasms/complications/*diagnosis/surgery
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Adrenalectomy
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Adrenocortical Adenoma/complications/*diagnosis/surgery
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Adrenocorticotropic Hormone/blood
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Adult
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Circadian Rhythm
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Cushing Syndrome/*diagnosis/etiology/physiopathology
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Diagnosis, Differential
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Endometrial Hyperplasia/*diagnosis
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Female
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Humans
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Hydrocortisone/secretion/urine