1.Quality Characteristics and Optimization of Rice Muffin Containing Chinese Artichoke (Stachys sieboldii MIQ) Powder Using Response Surface Methodology.
Young Il PARK ; Sun Mee LEE ; Nami JOO
Journal of the Korean Dietetic Association 2014;20(3):212-226
The purpose of this study was to determine the optimal composite recipe of rice muffin using three different amounts of Chinese artichoke (Stachys sieboldii MIQ) powder, brown sugar, and egg. Response surface methodology (RSM) was used to obtain 16 experimental points (including three replicates of Chinese artichoke powder, brown sugar, and egg), and the Chinese artichoke rice muffin formulation was optimized using rheology. The results of the sensory evaluation showed very significant values for color, texture, sweetness, and overall quality (P<0.05). The results of the color, texture, and chemical analyses showed significant values for crumb redness (P<0.01), crumb yellowness (P<0.05), crust redness (P<0.05), crust yellowness (P<0.001), crust lightness (P<0.05), adhesiveness (P<0.01), springiness (P<0.001), gumminess (P<0.01), cohesiveness (P<0.05), moisture content (P<0.05), and sweetness (P<0.05). As a result, optimum formulations obtained by numerical and graphical methods were found to be 8.28 g of Chinese artichoke powder, 66.20 g of brown sugar, 111.72 g of sticky rice powder, 30 g of rice powder, and 59.37 g of egg.
Adhesiveness
;
Asian Continental Ancestry Group*
;
Cynara scolymus*
;
Humans
;
Ovum
;
Rheology
2.Effects of material interfaces on orientation and function of fibrinogen.
Yong CHEN ; Jianfang REN ; Jianhua WU ; Ying FANG
Journal of Biomedical Engineering 2021;38(6):1087-1096
Fibrinogen (Fg) in human plasma plays an important role in hemostasis, vascular repair and tissue integrity. The surface chemistry of extracellular matrix or biological materials affects the orientation and distribution of Fg, and changes the exposure of integrin binding sites, thereby affecting its adhesion function to platelets. Here, the quantity, morphology and side chain exposure of Fg adsorbed on hydrophilic, hydrophobic and avidin surfaces were measured by atomic force microscopy (AFM) and flow cytometry (FCM), then the rolling behavior of platelets on Fg was observed through a parallel plate flow chamber system. Our results show that the hydrophobic surface leads to a large amount of cross-linking and aggregation of Fg, while the hydrophilic surface reduces the adsorption and accumulation of Fg while causing the exposure and spreading of the α chain on Fg and further mediating the adhesion of platelets. Fg immobilized by avidin / biotin on hydrophilic surface can maintain the monomer state, avoid over exposure and stretching of α chain, and bind to the platelets activated by the A1 domain of von Willebrand factor instead of inactivated platelets. This study would be helpful for improving the blood compatibility of implant biomaterials and reasonable experimental design of coagulation
Adsorption
;
Blood Platelets
;
Fibrinogen
;
Humans
;
Platelet Adhesiveness
;
von Willebrand Factor
3.A COMPARATIVE STUDY ON THE COMPOSITE RESTORATION DESIGN AND PLACEMENT METHODS USING THREE DIMENSIONAL FINITE ELEMENT ANALYSIS.
Jung Taek LEE ; Soon Ho YIM ; Lk Tae CHANG
The Journal of Korean Academy of Prosthodontics 1998;36(1):133-149
Clinical application on composite resin recently draw great concerns in dentistry. Especially due to advantages such as esthetics, adhesiveness, simple clinical procedures, various shapes and kinds of composite resin are widely being applied to prosthodontics, conservative dentistry, and orthodontics. But, clinical problems attributable to the polymerization shrin-kage of composite resin have been proposed, and we have to regard clinical problems such as secondary caries, loss of restoration, fracture of the surrounding tooth structure, marginal discoloration, and tooth sensitivity, and many portions are remained to be over-come. Therefore, this study attempts to analyze stress distribution between resin and tooth structure which is generated during polymerization shrinkage of composite resin using three dimensional finite element method. Three dimensional finite element models with conventional box-shape cavity and ero-sion/abrasion type V-shape lesion cavity in upper central incisor were developed. These cavities were filled with four different types of placement techniques. (bulk filling, horizontal increment filling, oblique occlusal increment filling, oblique gingival increment filling) The stresses generated by polymerization shrinkage of composite resin were calculated. The results analyzed with three dimensional finite element method were as follows : 1. The increment filling technique showed the highest maximum normal stress in both conventional box-shape and V-shape cavities and showed a tendency to decrease after complete polymerization. 2. The bulk filling technique resulted in increased stresses during the curing process in both conventional box-shape and V-shape cavities and the highest maximum normal stress occurred after complete polymerization. 3. The bulk filling resulted in the lowest maximum normal stress in both box-shape and V-shape cavities 4. Regardless of placement method, in conventional box-shape cavity, the maximum normal stress increased in dentin floor, enamel, dentin sequence and in V-shape cavity, the maximum normal stress increased in enamel, dentin sequence.
Adhesiveness
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Dental Enamel
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Dentin
;
Dentistry
;
Esthetics
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Finite Element Analysis*
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Incisor
;
Orthodontics
;
Polymerization
;
Polymers
;
Prosthodontics
;
Tooth
4.A STUDY ON THE EFFECTS TEXTURE OF FOOD ON CHEWING MOVEMENTS AND EMG OF MASTICATORY MUSCLE.
Lee Ra CHO ; Kwang Nam KIM ; Ik Tae CHANG ; Seong Joo HEO
The Journal of Korean Academy of Prosthodontics 1998;36(3):427-452
To elucidate the effects of food texture such as hardness, cohesiveness, adhesiveness on mastication procedure, the electromyographic activity (EMG) of the masticatory muscles and the chewing movements were analyzed in eighteen young subjects during ordinary chewing. Seven different foods were selected by sensory texture profiling and mechanical test with texturometer; egg white, sausage, pizza cheese, yang-geng, biscuit, peanut and almond. The indexes of jaw movements used were the chewing number, chewing time, maximum opening, average opening, closing velocity and opening velocity. The EMG indexes analyzed were maximum and average integrated amplitude of the anterior temporal and masseter muscles. The results obtained were as follows. 1. The chewing time and chewing number, mandibular displacement and mandibular movement velocity were not changed by the hardness, cohesiveness and adhesiveness of the food (p>0.05). 2. The harder food materials showed a higher amplitude of the anterior temporal muscle integrated EMGs than the softer ones (p<0.05). 3. The maximum and average integrated EMGs of the masseter muscle increased with the increase of hardness of the food (p<0.05). 4. The integrated EMGs of preferred side and non-preferred side masticatory muscles increased with the increase of hardness of the food (p<0.05). 5. The adhesiveness and cohesiveness of the food were not the determining factor to the integrated EMGs of masticatory muscles (p<0.05).
Adhesiveness
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Cheese
;
Egg White
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Hardness
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Jaw
;
Masseter Muscle
;
Mastication*
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Masticatory Muscles*
;
Prunus dulcis
;
Temporal Muscle
5.Comparison Study of Physical Properties between Two Silicone Gel Sheets.
Young Mook YUN ; Nak Heon KANG ; Tae Joon KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2008;35(6):659-662
PURPOSE: Silicone gel sheet(SGS) is used for preventing and treating keloid or hypertrophic scars. Because the product is weak in tear strength and adherence, it requires several replacements, which requires high cost. As a solution for this problem, we developed a new silicone gel sheet, named as Scar Clinic, and confirmed its physical properties. METHODS: Tensile strength, elongation rate, adhesiveness, and water vapor transmission rate were experimentally compared between the most commonly used SGS product and the Scar Clinic. RESULTS: The newly developed SGS showed better results compared to the existed SGS in regards to tensile strength, elongation rate, adhesiveness, and water vapor transmission rate. CONCLUSION: The Scar Clinic showed higher durability and flexibility. It will be a useful product for treating scars clinically.
Adhesiveness
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Cicatrix
;
Cicatrix, Hypertrophic
;
Keloid
;
Pliability
;
Silicone Gels
;
Steam
;
Tensile Strength
6.Comparison of Scarclinic-thin(TM) and Scarclinic(TM) in Terms of Scar Improvement: A pilot study.
Sang Kyun LEE ; Seung Kyu HAN ; Woo Kyung KIM
Archives of Aesthetic Plastic Surgery 2012;18(1):51-56
Silicone gel sheets are widely used to treat keloids and hypertrophic scars. Scarclinic(TM) is a type of silicone gel sheet developed in Korea, and has been shown to improve the appearance of scars. However, Scarclinic(TM) has demerits that include weak adhesiveness, a color that differs from skin, and too great a thickness. Scarclinic-thin(TM) was recently developed with these disadvantages in mind. The purpose of this pilot study was to compare the effects of Scarclinic-thin(TM) and Scarclinic(TM) on scar appearance and wearer's comfort. From April 2010 to May 2010, Scarclinic-thin(TM) and Scarclinic(TM) were applied to treat a single scar in each of 8 patients. One half of each scar was treated with Scarclinic-thin(TM) and the other with Scarclinic(TM). After 3 months, scar quality and wearer's comfort were evaluated using the Vancouver Scar Scale(VSS) and an objective self-assessment scale (OSAS). Mean Vancouver Scar Scale scores for Scarclinic(TM) and Scarclinic-thin(TM) at 3 months were 3.4+/-1.3 and 3.3+/-2.0, respectively, and mean objective self-assessment scale scores were 21.7+/-4.5 and 22.3+/-2.9, respectively. No statistically significant difference was observed between Scarclinic(TM) and Scarclinic-thin(TM) in terms of Vancouver Scar Scale or objective self-assessment scale scores(p=0.83 and 0.70, respectively). Scarclinic-thin(TM) and Scarclinic(TM) are similar in terms of their scar improving effects and wearer's comfort.
Adhesiveness
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Cicatrix
;
Cicatrix, Hypertrophic
;
Humans
;
Keloid
;
Korea
;
Pilot Projects
;
Self-Assessment
;
Silicone Gels
;
Skin
7.Effects of Dimethyl Sulfoxide on the Differentiation of Myocardial and Endothelial Cells.
Dong Hyup LEE ; Yee Tae PARK ; Sung Sae HAN ; Yung Chang LEE
Yeungnam University Journal of Medicine 1988;5(2):111-119
To elucidate the effects of dimethyl sulfoxide on of myocardial and endothelial cells in culture, the cells were exposed to 10% dimethyl sulfoxide in culture medium for 1 hour at 48 hours after cell isolation. The general morphology and the cytochemical reaction of marker enzymes for mitochondria and Golgi complexes were investigated. The results were summarized as follows 1. DMSO induced elongation and narrowing of the cells and increase of mitochondrial reaction in myocardial cells. 2. DMSO induced destruction and disruption of myofibrils in myocardial cells resulting in increase of contractile activities. 3. In the endothelial cells, DMSO suppressed proliferative activities but thiamine pyrophosphatase reactions were enhanced indicating increase of Golgi complex activity. 4. DMSO seemed to hamper with the adhesiveness and motility of the endothelial cells causing the decrease of the number of cells in vitro.
Adhesiveness
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Cell Separation
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Dimethyl Sulfoxide*
;
Endothelial Cells*
;
Golgi Apparatus
;
In Vitro Techniques
;
Mitochondria
;
Myofibrils
;
Thiamine Pyrophosphatase
8.Microstructure and adhesion of HAP-glass-alumina composite gradient bioceramics coating.
Zhiqiang WANG ; Xiaoxu CHEN ; Yingji CAI ; Bingling LÜ
Journal of Biomedical Engineering 2005;22(1):70-73
HAP-Glass-alpha-Al2O3 gradient coating on alumina ceramics substrate was prepared by multi-layer slurry-dipping and sintering process, effects of the composition of the coating on the microstructure and adhesion strength of the gradient coating were studied. R2O-Al2O3-B2O3-SiO2 system glass with low softening temperature and thermal expansion was used in the gradient coating. The composition of the coating was varied from interface to surface layer, i.e. the HAP concentration increased and glass concentration decreased gradually from the under layer to the surface layer. A suitable amount superfine alpha-Al2O3 was added in the gradient coating to reinforce the bonding strength between the coating and substrate. The results show that the use of R2O-Al2O3-B2O3-SiO2 system glass is propitious to sintering the coating at low temperature and to combination between the coating and substrate. The addition of superfine alpha-Al2O3 can reinforce the bonding strength between the coating and substrate, the highest bonding strength is about 48.2 MPa.
Adhesiveness
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Aluminum Oxide
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chemistry
;
Ceramics
;
chemistry
;
Coated Materials, Biocompatible
;
chemistry
;
Durapatite
;
chemistry
;
Glass
;
chemistry
9.Analysis of Grey correlation between surface energy and adhesive characteristic of platelet for DLC.
Bogang LI ; Jie YIN ; Juanjuan NA ; Guangfu YIN ; Changqiong ZHENG
Journal of Biomedical Engineering 2005;22(1):20-24
In this study, the diamond like carbon (DLC) samples made from different processes and processing conditions, were subjected to the test of platelet adhesion. The surface energy parameters such as surface tension, critical surface tension, interface tension, adhesive power, and polar branch and chromatic dispersion branch of surface tension based on determining balanced contact angle of ethanol, water and different ratios of ethanol/water solution on surfaces of the samples were calculated, respectively. Then the effects of these parameters on the amounts and deformation index of the platelets adhering to the samples were assessed by analyzing the T-type correlation degree in the Grey system. The results showed: (1) all degrees of correlation between surface energy parameters and adhesion amounts of platelet are positive, but for deformation index, the correlation degrees are negative except for critical surface tension; (2) the adhesion amounts of platelet increase with the rising polar branch of surface tension, while the deformation index increases with rising chromatic dispersion branch of surface tension; (3) Both adhesion amounts and deformation index of platelet are positively correlated with critical surface tension to a higher degrees; (4) the effects of polar branch of surface tension on adhesion amounts and deformation index of platelet keep pace with the surface tension, interface tension and adhesive power. Thus two important conclusions have been obtained: (1) the adhesive characteristic of platelets to the surface of DLC is closely related with the surface energy of DLC; the hemocompatibility of DLC is decided by the balance between the polarity of DLC surface and the limited humidifying water on the surface; there is a blood compatible range delimited by critical surface tension; (2) adhesion and deformation of platelets on surface of DLC have different energy mechanism: polar surface is advantageous to the adhesion, while the deformation is achieved with the aid of chromatic dispersion action stem from the surface.
Biocompatible Materials
;
chemistry
;
Carbon
;
chemistry
;
Diamond
;
chemistry
;
Humans
;
Materials Testing
;
Platelet Adhesiveness
;
Surface Properties
10.Study on adhesion of platelets to surface of copoly(benzyl glutamate-hydroxy ethyl glutamine).
Shirong PAN ; Wu YI ; Qinmei WANG
Journal of Biomedical Engineering 2002;19(4):572-575
Copoly (benzyl glutamate-hydroxy ethyl glutamine) were prepared by partially aminolysis of poly benzyl glutamate with hydroxyl ethylamine at 60 degrees C for predeternined period. As aminolysis was proceeding, the content of hydroxy ethyl glutamine in copolymer increased and the yield of aminolysis decreased. When aminolysis time reached 16.5 hours, a copolymer with 0.357 mole fraction of hydroxy ethyl glutamine was obtained. After 16.5 hours a soluble yellow viscous product of reaction was obtained. The aminolysized specimens displayed more swelling degree in water, that is, more hydrophilits. The meassurement of solid-liquid contact angles showed that an increase in critical surface tention with content of hydroxy ethyl glutamine in copolymer was observed. Likewise a obvious increase in polar component and a slight decrease in dispersive of surface free energy, thus an increase in total surface free energy with content of hydroxy ethyl glutamine was found. The platelet adhesion and deformation test indicated that less platelets were adhered to surfaces of all aminolysized specimens than that of both poly benzyl glutamate and polydimethylsilicone. The least adhered platelets on surface of copolymer with 0.133 mole fraction of content of hydroxy ethyl glutamine were observed. The partiall aminolysis of poly benzyl glutamate films is an effective method to improve its hydrophility and antithrombogenicity.
Animals
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In Vitro Techniques
;
Male
;
Materials Testing
;
Platelet Adhesiveness
;
Polyglutamic Acid
;
analogs & derivatives
;
chemistry
;
Rabbits
;
Surface Properties