The purpose of this study was to determine the optimal composite recipe of rice muffin using three different amounts of Chinese artichoke (Stachys sieboldii MIQ) powder, brown sugar, and egg. Response surface methodology (RSM) was used to obtain 16 experimental points (including three replicates of Chinese artichoke powder, brown sugar, and egg), and the Chinese artichoke rice muffin formulation was optimized using rheology. The results of the sensory evaluation showed very significant values for color, texture, sweetness, and overall quality (P<0.05). The results of the color, texture, and chemical analyses showed significant values for crumb redness (P<0.01), crumb yellowness (P<0.05), crust redness (P<0.05), crust yellowness (P<0.001), crust lightness (P<0.05), adhesiveness (P<0.01), springiness (P<0.001), gumminess (P<0.01), cohesiveness (P<0.05), moisture content (P<0.05), and sweetness (P<0.05). As a result, optimum formulations obtained by numerical and graphical methods were found to be 8.28 g of Chinese artichoke powder, 66.20 g of brown sugar, 111.72 g of sticky rice powder, 30 g of rice powder, and 59.37 g of egg.
Adhesiveness ; Asian Continental Ancestry Group* ; Cynara scolymus* ; Humans ; Ovum ; Rheology

Fibrinogen (Fg) in human plasma plays an important role in hemostasis, vascular repair and tissue integrity. The surface chemistry of extracellular matrix or biological materials affects the orientation and distribution of Fg, and changes the exposure of integrin binding sites, thereby affecting its adhesion function to platelets. Here, the quantity, morphology and side chain exposure of Fg adsorbed on hydrophilic, hydrophobic and avidin surfaces were measured by atomic force microscopy (AFM) and flow cytometry (FCM), then the rolling behavior of platelets on Fg was observed through a parallel plate flow chamber system. Our results show that the hydrophobic surface leads to a large amount of cross-linking and aggregation of Fg, while the hydrophilic surface reduces the adsorption and accumulation of Fg while causing the exposure and spreading of the α chain on Fg and further mediating the adhesion of platelets. Fg immobilized by avidin / biotin on hydrophilic surface can maintain the monomer state, avoid over exposure and stretching of α chain, and bind to the platelets activated by the A1 domain of von Willebrand factor instead of inactivated platelets. This study would be helpful for improving the blood compatibility of implant biomaterials and reasonable experimental design of coagulation
Adsorption ; Blood Platelets ; Fibrinogen ; Humans ; Platelet Adhesiveness ; von Willebrand Factor

OBJECTIVE: To evaluate the effects of physical properties of foods on the changes of viscosity and mass as well as the particle size distribution after mastication. METHOD: Twenty subjects with no masticatory disorders were recruited. Six grams of four solid foods of different textures (banana, tofu, cooked-rice, cookie) were provided, and the viscosity and mass after 10, 20, and 30 cycles of mastication and just before swallowing were measured. The physical properties of foods, such as hardness, cohesiveness, and adhesiveness, were measured with a texture analyzer. Wet sieving and laser diffraction were used to determine the distribution of food particle size. RESULTS: When we measured the physical characteristics of foods, the cookie was the hardest food, and the banana exhibited marked adhesiveness. Tofu and cooked-rice exhibited a highly cohesive nature. As the number of mastication cycles increased, the masses of all foods were significantly increased (p<0.05), and the viscosity was significantly decreased in the case of banana, tofu, and cooked-rice (p<0.05). The mass and viscosity of all foods were significantly different between the foods after mastication (p<0.05). Analyzing the distribution of the particle size, that of the bolus was different between foods. However, the curves representing the particle size distribution for each food were superimposable for most subjects. CONCLUSION: The viscosity and particle size distribution of the bolus were different between solid foods that have different physical properties. Based on this result, the mastication process and food bolus formation were affected by the physical properties of the food.
Adhesiveness ; Deglutition ; Hardness ; Mastication ; Musa ; Particle Size ; Rheology ; Soy Foods ; Viscosity

To elucidate the effects of dimethyl sulfoxide on of myocardial and endothelial cells in culture, the cells were exposed to 10% dimethyl sulfoxide in culture medium for 1 hour at 48 hours after cell isolation. The general morphology and the cytochemical reaction of marker enzymes for mitochondria and Golgi complexes were investigated. The results were summarized as follows 1. DMSO induced elongation and narrowing of the cells and increase of mitochondrial reaction in myocardial cells. 2. DMSO induced destruction and disruption of myofibrils in myocardial cells resulting in increase of contractile activities. 3. In the endothelial cells, DMSO suppressed proliferative activities but thiamine pyrophosphatase reactions were enhanced indicating increase of Golgi complex activity. 4. DMSO seemed to hamper with the adhesiveness and motility of the endothelial cells causing the decrease of the number of cells in vitro.
Adhesiveness ; Cell Separation ; Dimethyl Sulfoxide* ; Endothelial Cells* ; Golgi Apparatus ; In Vitro Techniques ; Mitochondria ; Myofibrils ; Thiamine Pyrophosphatase

Clinical application on composite resin recently draw great concerns in dentistry. Especially due to advantages such as esthetics, adhesiveness, simple clinical procedures, various shapes and kinds of composite resin are widely being applied to prosthodontics, conservative dentistry, and orthodontics. But, clinical problems attributable to the polymerization shrin-kage of composite resin have been proposed, and we have to regard clinical problems such as secondary caries, loss of restoration, fracture of the surrounding tooth structure, marginal discoloration, and tooth sensitivity, and many portions are remained to be over-come. Therefore, this study attempts to analyze stress distribution between resin and tooth structure which is generated during polymerization shrinkage of composite resin using three dimensional finite element method. Three dimensional finite element models with conventional box-shape cavity and ero-sion/abrasion type V-shape lesion cavity in upper central incisor were developed. These cavities were filled with four different types of placement techniques. (bulk filling, horizontal increment filling, oblique occlusal increment filling, oblique gingival increment filling) The stresses generated by polymerization shrinkage of composite resin were calculated. The results analyzed with three dimensional finite element method were as follows : 1. The increment filling technique showed the highest maximum normal stress in both conventional box-shape and V-shape cavities and showed a tendency to decrease after complete polymerization. 2. The bulk filling technique resulted in increased stresses during the curing process in both conventional box-shape and V-shape cavities and the highest maximum normal stress occurred after complete polymerization. 3. The bulk filling resulted in the lowest maximum normal stress in both box-shape and V-shape cavities 4. Regardless of placement method, in conventional box-shape cavity, the maximum normal stress increased in dentin floor, enamel, dentin sequence and in V-shape cavity, the maximum normal stress increased in enamel, dentin sequence.
Adhesiveness ; Dental Enamel ; Dentin ; Dentistry ; Esthetics ; Finite Element Analysis* ; Incisor ; Orthodontics ; Polymerization ; Polymers ; Prosthodontics ; Tooth

To elucidate the effects of food texture such as hardness, cohesiveness, adhesiveness on mastication procedure, the electromyographic activity (EMG) of the masticatory muscles and the chewing movements were analyzed in eighteen young subjects during ordinary chewing. Seven different foods were selected by sensory texture profiling and mechanical test with texturometer; egg white, sausage, pizza cheese, yang-geng, biscuit, peanut and almond. The indexes of jaw movements used were the chewing number, chewing time, maximum opening, average opening, closing velocity and opening velocity. The EMG indexes analyzed were maximum and average integrated amplitude of the anterior temporal and masseter muscles. The results obtained were as follows. 1. The chewing time and chewing number, mandibular displacement and mandibular movement velocity were not changed by the hardness, cohesiveness and adhesiveness of the food (p>0.05). 2. The harder food materials showed a higher amplitude of the anterior temporal muscle integrated EMGs than the softer ones (p<0.05). 3. The maximum and average integrated EMGs of the masseter muscle increased with the increase of hardness of the food (p<0.05). 4. The integrated EMGs of preferred side and non-preferred side masticatory muscles increased with the increase of hardness of the food (p<0.05). 5. The adhesiveness and cohesiveness of the food were not the determining factor to the integrated EMGs of masticatory muscles (p<0.05).
Adhesiveness ; Cheese ; Egg White ; Hardness ; Jaw ; Masseter Muscle ; Mastication* ; Masticatory Muscles* ; Prunus dulcis ; Temporal Muscle

Silicone gel sheets are widely used to treat keloids and hypertrophic scars. Scarclinic(TM) is a type of silicone gel sheet developed in Korea, and has been shown to improve the appearance of scars. However, Scarclinic(TM) has demerits that include weak adhesiveness, a color that differs from skin, and too great a thickness. Scarclinic-thin(TM) was recently developed with these disadvantages in mind. The purpose of this pilot study was to compare the effects of Scarclinic-thin(TM) and Scarclinic(TM) on scar appearance and wearer's comfort. From April 2010 to May 2010, Scarclinic-thin(TM) and Scarclinic(TM) were applied to treat a single scar in each of 8 patients. One half of each scar was treated with Scarclinic-thin(TM) and the other with Scarclinic(TM). After 3 months, scar quality and wearer's comfort were evaluated using the Vancouver Scar Scale(VSS) and an objective self-assessment scale (OSAS). Mean Vancouver Scar Scale scores for Scarclinic(TM) and Scarclinic-thin(TM) at 3 months were 3.4+/-1.3 and 3.3+/-2.0, respectively, and mean objective self-assessment scale scores were 21.7+/-4.5 and 22.3+/-2.9, respectively. No statistically significant difference was observed between Scarclinic(TM) and Scarclinic-thin(TM) in terms of Vancouver Scar Scale or objective self-assessment scale scores(p=0.83 and 0.70, respectively). Scarclinic-thin(TM) and Scarclinic(TM) are similar in terms of their scar improving effects and wearer's comfort.
Adhesiveness ; Cicatrix ; Cicatrix, Hypertrophic ; Humans ; Keloid ; Korea ; Pilot Projects ; Self-Assessment ; Silicone Gels ; Skin

PURPOSE: Adhesion after flexor tendon injury is a result of fibrosis between tendon and tendon sheath. This, finally interfere with gliding mechanism of tendon and results in functional problem of hands. Therefore, there have been many trials to reduce adhesion around the tendon. However, there is no standard procedure clinically practiced in hospitals. Mitomycin-C is an antineoplastic alkylating agent that decrease fibroblast proliferation and scar formation. It is commonly used in many surgery to reduce postoperative adhesion. This study was designed to observe the effect of Mitomycin-C on preventing adhesion in injured flexor tendon. METHODS: The deep flexor tendon of digit 2 and 4 in the left forepaw of 15 New Zealand White rabbits were subjected to partial tenotomy. In study group, injury site was exposed to a single 5-minute application of Mitomycin-C, and in control group was left untreated. Digit 2 and 4 in the right forepaw of each rabbit were considered as non-adhesion control group. After 2 weeks, the animals were sacrificed and digits were amputated for biomechanical test and histological study. RESULTS: In biomechanical study to measure yield point, mean yield point of non-adhesion control was 17.43+/-2.33 and 25.07+/-4.03 for adhesion control, which proves increase of adhesion in adhesion control group(p<0.05) in 95% confidence. In Mitomycin-C group, mean yield point was 12.71+/-4.97. Compared with adhesion control, there was decrease in adhesiveness in Mitomycin-C group(p<0.05) in 95% confidence. In histological study, the result of adhesion control revealed massive adhesions of bony structure, fibrotic tissue and tendon structure with ablation of the border. However in Mitomycin-C group, we could find increased fibrotic tissue, but adhesion is much lesser than adhesion group and borders between structures remain intact. CONCLUSION: This study suggests that Mitomycin-C can significantly reduce adhesion of injured flexor tendon in rabbit model.
Adhesiveness ; Animals ; Cicatrix ; Fibroblasts ; Fibrosis ; Hand ; Mitomycin ; Rabbits ; Tendon Injuries ; Tendons ; Tenotomy

Adhesive forces between the retina and the retinal pigment epithelium, which is mainta ined by active mechanisms unique for living animals, deteriorates rapidly after death and leads to spontaneous retinal detachment. Change of retinal adhesiveness in rabbits after death was investigated using a new method. Retinal detachment was induced by applying various levels of aspiration power from 0 to 1OO mmHg to the vitreous cavity using a vitrectomy instrument immediately after the rabbit was killed without enucleation. And the time required for creating the retinal detachment was measured. Retinal adhesiveness deteriorated and spontaneous retinal detachment occurred 28 minutes and 35 seconds after death confirming the active adhesion between the retina and the retinal pigment epithelium before death Increase of aspiration power led to shortening of time required for creating retinal detachment. From aspiration powers of 0 to 100 mmHg, the common logarithm of time required for retinal detachment was inversely proportional to the aspiration power [IogY = 1.45215 - 0.01113X, (R2=0.99041), X: aspiration power (mmHg), Y: time required for creating retinal detachment (minutes)]. Thus, presumed time of retinal detachment could be estimated between the aspiration powers of 0 to 100 mmHg.
Adhesiveness ; Adhesives* ; Animals ; Postmortem Changes* ; Rabbits ; Retina* ; Retinal Detachment ; Retinal Pigment Epithelium* ; Retinaldehyde* ; Vitrectomy

PURPOSE: Silicone gel sheet(SGS) is used for preventing and treating keloid or hypertrophic scars. Because the product is weak in tear strength and adherence, it requires several replacements, which requires high cost. As a solution for this problem, we developed a new silicone gel sheet, named as Scar Clinic, and confirmed its physical properties. METHODS: Tensile strength, elongation rate, adhesiveness, and water vapor transmission rate were experimentally compared between the most commonly used SGS product and the Scar Clinic. RESULTS: The newly developed SGS showed better results compared to the existed SGS in regards to tensile strength, elongation rate, adhesiveness, and water vapor transmission rate. CONCLUSION: The Scar Clinic showed higher durability and flexibility. It will be a useful product for treating scars clinically.
Adhesiveness ; Cicatrix ; Cicatrix, Hypertrophic ; Keloid ; Pliability ; Silicone Gels ; Steam ; Tensile Strength