1.Pigmented Liver Cell Adenoma with Nodule-in-Nodule Appearance: Case Report.
Hyun Jun CHOI ; Jun Hyun YUN ; Ji Hyeo CHOI ; Ju Hyun IM ; Se Jong KIM ; Byung Ran PARK ; Jae Hong KIM ; Kyung Soo KIM
Journal of the Korean Radiological Society 2004;51(3):317-320
Pigmented liver cell adenoma is very rare benign hepatic tumor and only four cases have been reported in the literature until now. We experienced one case of pigmented liver cell adenoma with nodule-in-nodule appearance, and we report on the ultrasonographic, CT and pathologic findings.
Adenoma, Liver Cell*
;
Liver*
2.Malignant Transformation of Inflammatory Hepatocellular Adenoma into Hepatocellular Carcinoma.
Young Ju LEE ; Jin Woo JOO ; Jun Yong PARK
The Korean Journal of Gastroenterology 2018;72(5):267-270
No abstract available.
Adenoma, Liver Cell*
;
Carcinoma, Hepatocellular*
3.Hepatocellular carcinoma: risk factors and precursor lesions
Journal of Practical Medicine 2003;458(8):16-20
Introduce risk factors of hepatocellular carcinoma included infection of hepatitis B virus or hepatitis C virus, and coinfaction of hepatitis B virus and hepatitis C virus, mechanisms malignant transformations and pre-malignant lesions such as cirrhosis, pathohistological signs, structural and cytological changes
Carcinoma, Hepatocellular
;
Carcinoma
;
Adenoma, Liver Cell
4.Hepatocellular Adenoma and Focal Nodular Hyperplasia.
Korean Journal of Medicine 2013;84(3):325-332
Recent advances in imaging technologies have offered us a great chance to detect a variety of focal liver lesions. Accordingly, it is of paramount importance to determine whether these focal liver lesions are malignant or nonmalignant. Some benign hepatic tumors mimicking hepatocellular carcinoma typically develop from either regenerative or dysplastic/neoplastic processes. The most common benign hepatic solid tumors that are not of vascular origin include focal nodular hyperplasia and hepatocellular adenoma. A majority of patients with benign hepatic tumors are often asymptomatic and require no specific treatment. However, surgical resection may be infrequently needed for cases with clinical symptoms or malignant potential. This review will touch on the epidemiology, pathogenesis, clinical features, diagnosis, and management of focal nodular hyperplasia and hepatocellular adenoma.
Adenoma, Liver Cell
;
Carcinoma, Hepatocellular
;
Focal Nodular Hyperplasia
;
Humans
;
Liver
7.Zollinger-Ellison Syndrome: A Case Report.
Dong Jin JUNG ; Hyun Kwon HA ; Pyo Nyun KIM ; Moon Gyu LEE ; Yong Ho AUH
Journal of the Korean Radiological Society 1999;41(6):1173-1176
Zollinger-Ellison syndrome (ZES) involves hypergastinemia produced by a gastrin-secreting tumor. Not only can it cause an ulcer but may also behave as a malignant lesion, metastasizing to the liver or other organs. The development of potent antisecretory agents for controlling acid secretion as well as techniques for localizing these islet cell tumors, has led to greatly improved survival rates. We describe a case of Zollinger-Ellison syndrome, emphasising the radiologic findings, and including a review of the literature.
Adenoma, Islet Cell
;
Liver
;
Survival Rate
;
Ulcer
;
Zollinger-Ellison Syndrome*
8.Atypical beta-Catenin Activated Child Hepatocellular Tumor.
Aynur TURAN ; Havva Akmaz UNLU ; Esra KARAKUS ; Arzu YAZAL ERDEM ; Zeynep Ilerisoy YAKUT
Pediatric Gastroenterology, Hepatology & Nutrition 2015;18(2):144-148
Hepatocellular adenomas are a benign, focal, hepatic neoplasm that have been divided into four subtypes according to the genetic and pathological features. The beta-catenin activated subtype accounts for 10-15% of all hepatocellular adenomas and specific magnetic resonance imaging features have been defined for different hepatocellular adenomas subtypes. The current study aimed to report the magnetic resonance imaging features of a well differentiated hepatocellular carcinoma that developed on the basis of beta-catenin activated hepatocellular adenomas in a child. In this case, atypical diffuse steatosis was determined in the lesion. In the literature, diffuse steatosis, which is defined as a feature of the hepatocyte nuclear factor-1alpha-inactivated hepatocellular adenomas subtype, has not been previously reported in any beta-catenin activated hepatocellular adenomas case. Interlacing magnetic resonance imaging findings between subtypes show that there are still many mysteries about this topic and larger studies are warranted.
Adenoma
;
Adenoma, Liver Cell
;
beta Catenin*
;
Carcinoma, Hepatocellular
;
Child*
;
Hepatocytes
;
Humans
;
Liver
;
Liver Neoplasms
;
Magnetic Resonance Imaging
9.A Case of Hepatocellular Adenoma.
Jong Eun YEON ; Shang Hoon PARK ; Jin Ho KIM ; So Young KWON ; Kwan Soo BYUN ; Chang Hong LEE ; Sang Yong CHOI ; Cheol Min PARK ; In Ho CHA ; Nam Hee WON
Korean Journal of Medicine 1997;52(1):131-136
Hepatocelluar adenoma is a rare benign tumor, the incidence of which has increased since the introduction of oral contraceptives. We recently experienced a case of hepatocellular adenoma with ovarian Mucinous cystadenoma in a 36 year old female patient who had no history of oral contraceptives usage. The radiologic and pathologic differential diagnosis is discussed in this patient.
Adenoma
;
Adenoma, Liver Cell*
;
Adult
;
Contraceptives, Oral
;
Cystadenoma, Mucinous
;
Diagnosis, Differential
;
Female
;
Humans
;
Incidence
;
Ovary
10.Hepatocellular Carcinoma Arising in a Huge Hepatocellular Adenoma with Bone Marrow Metaplasia
Hyo Jeong KANG ; Hui Jeong JEONG ; So Woon KIM ; Eunsil YU ; Young Joo LEE ; So Yeon KIM ; Jihun KIM
Journal of Pathology and Translational Medicine 2018;52(4):226-231
Hepatocellular adenoma (HCA) is the most common type of benign liver tumor, and its major complication is malignant transformation to hepatocellular carcinoma (HCC). Here, we report a case of HCC arising in HCA with bone marrow metaplasia in a 24-year-old Korean woman who presented with abdominal discomfort. A huge liver mass was found on abdominal ultrasonography. She underwent surgical hepatic resection, and the resected specimen was entirely involved by a 20-cm-sized tumor. Histological review revealed a well differentiated HCC arising from inflammatory HCA with β-catenin nuclear positivity and bone marrow metaplasia that contained hematopoietic cells. This case was unique because malignant transformation, inflammatory type HCA, β-catenin nuclear staining, and bone marrow metaplasia were simultaneously observed. Additionally, it should be noted that a large HCA with β-catenin activation can undergo malignant transformation and should be surgically resected in a timely manner.
Adenoma, Liver Cell
;
Bone Marrow
;
Carcinoma, Hepatocellular
;
Female
;
Humans
;
Liver
;
Metaplasia
;
Ultrasonography
;
Young Adult