1.A Case of Polymorphous Low Grade Adenocarcinoma Arising from Warthin's Tumor.
Kang Dae LEE ; Hyoung Shin LEE ; Hyo Sung MUN ; Bang HEU
Korean Journal of Otolaryngology - Head and Neck Surgery 2006;49(2):232-235
Warthin's tumor is the second most common benign tumor of the parotid gland. Malignancy arising from Warthin's tumor is extremely rare, and only 29 cases have been reported. Diagnosis can be made prior to the surgery, but in many cases, the disease is detected through postoperative pathology report or by recurrence of the mass lesion. We report a case of polymorphous low grade adenocarcinoma arising from Warthin's tumor diagnosed by the excision of a parotid mass and treated by an additional surgery of superficial parotidectomy. The postoperative pathology report revealed no residual cancer cells and the patient is free of disease for 8 months since the operation.
Adenocarcinoma*
;
Adenolymphoma
;
Diagnosis
;
Humans
;
Neoplasm, Residual
;
Parotid Gland
;
Pathology
;
Recurrence
3.Parotid adenolymphoma: the enhanced MSCT manifestations and clinical pathological analysis.
Jiang SHEN ; Heng SHAO ; Dongsheng WU ; Lu LIU ; Chunhua XU ; Xiaoling WEN
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(24):2129-2132
OBJECTIVE:
To investigate the imaging manifestations of 16-slice enhanced CT of parotid adenolymphoma in the parotid gland and the corresponding pathology,in order to improve the understanding of the CT imaging manifestations of parotid adenolymphoma in the parotid gland.
METHOD:
The enhanced CT characteristics of 34 cases of parotid adenolymphoma in the parotid gland confirmed by histological pathology were retrospectively analyzed.
RESULT:
There were totally 86 lesions in 34 cases, of which 12 cases with lesions in bilateral sides and 22 cases with lesions in unilateral side. Sixty-six lesions located behind and below the superficial lobe of the parotid gland. The lesions showed moderate to obvious enhancement at arterial phase, and the cystic region within the lesions showed no enhancement.
CONCLUSION
The relatively specific enhanced MSCT manifestations of parotid adenolymphoma in parotid gland include lesions located behind and below the superficial lobe of parotid gland unilaterally or bilaterally, sometimes exhibited as multiple masses, with clear edge, obvious enhancement and cystic degeneration inside.
Adenolymphoma
;
diagnosis
;
pathology
;
Humans
;
Parotid Gland
;
pathology
;
Parotid Neoplasms
;
diagnosis
;
pathology
;
Tomography, X-Ray Computed
5.Lymphadenoma Arising in the Parotid Gland: A Case Report.
Ghee Young KWON ; Eo Jin KIM ; Jai Hyang GO
Yonsei Medical Journal 2002;43(4):536-538
We report a case of lymphadenoma arising in the parotid gland. A 53-year-old female patient presented with a mass in the parotid gland. Grossly, it was a well-demarcated solid mass measuring 3 cm in diameter. Microscopic examination revealed many cysts or duct-like structures in the background of the prominent lymphoid stroma, confirming a diagnosis of lymphadenoma. This particular case was thought to have arisen from an intraparotid lymph node. Lymphadenoma is a rare benign neoplasm of the salivary gland with partial resemblance to other salivary gland tumors, such as Warthin's tumor, cystadenoma, sebaceous lymphadenoma or mucoepidermoid carcinoma. Therefore proper recognition of this rare entity is warranted to avoid confusion in the diagnosis.
Adenolymphoma/*pathology
;
Case Report
;
Female
;
Human
;
Middle Age
;
Salivary Gland Neoplasms/*pathology
6.Warthin tumor complicated with T-lymphoblastic lymphoma: a case report.
Yue XI ; Yuting MA ; Zhigang YAO ; Yejun QIN ; Miaoqing ZHAO
West China Journal of Stomatology 2022;40(6):727-730
Warthin tumor is a benign salivary gland tumor comprising ductal epithelium and lymphoid stroma. To date, reports about the malignant transformations of intraepithelial and lymphoid components in Warthin tumor are extremely rare; lymphoid malignant transformation into B-cell lymphoma is particularly rare in combination with T-cell lymphoma. The case of Warthin tumor complicated with T-lymphoblastic lymphoma is reported to emphasize the importance of a careful light microscopic evaluation of lymphoid tissue in Warthin tumor for identifying occult lymphoma presence, reducing misdiagnosis and missed diagnosis, and determining a timely treatment.
Humans
;
Adenolymphoma/pathology*
;
Parotid Neoplasms/pathology*
;
Salivary Gland Neoplasms
;
Epithelium/pathology*
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma/complications*
7.Warthin's tumor (adenolymphoma) with squamous metaplasia and carcinomatous transformation: report of a case.
Ming DU ; Guo-zhang MA ; Ming-hao NIE
Chinese Journal of Pathology 2005;34(12):827-827
Adenolymphoma
;
metabolism
;
pathology
;
surgery
;
Carcinoma, Squamous Cell
;
metabolism
;
pathology
;
surgery
;
Cell Transformation, Neoplastic
;
Humans
;
Keratins
;
metabolism
;
Ki-67 Antigen
;
metabolism
;
Male
;
Metaplasia
;
pathology
;
Middle Aged
;
Parotid Neoplasms
;
metabolism
;
pathology
;
surgery
8.Analysis of 2161 cases of neoplasm in oral maxillofacial region in Xinjiang.
Chinese Journal of Stomatology 2010;45(9):553-555
OBJECTIVETo investigate the incidence and constituent characteristic of neoplasm in oromaxillo-facial region in Xinjiang.
METHODSA total of 2161 patients with benign or malignant oral-maxillofacial tumors diagnosed in Department of Dentofacial Surgery of the First Affiliated Hospital of Xinjiang Medical College from 1995 to 2009 were analyzed retrospectively.
RESULTSOf the 2161 cases, 58.49% (1264/2161) was benign tumors, 33.13% (716/2161) malignant tumors, and 8.38% (181/2161) tumor-like lesions. The most common benign tumors were pleomorphic adenoma, hemangioma, papilloma, adenolymphoma and ameloblastoma. Squamous cell carcinoma constituted the majority of the malignant tumors. The most common malignant tumors of salivary gland were adenoid cystic carcinoma. The most common odontogenic tumors was ameloblastoma. The most common sites of malignant tumors were tongue, lip, parotiod gland and buccal mucosa.
CONCLUSIONSThe common pathological type of oral and maxillofacial benign neoplasm and the most common sites of malignancy in Xinjiang region were similar to those of other places inside and outside the country. Adenoid cystic carcinoma was more common than other salivary originated tumors. There was more malignant tumors in Uygur nationality than in Han living in the same region.
Adenolymphoma ; Adenoma, Pleomorphic ; Ameloblastoma ; Carcinoma, Adenoid Cystic ; epidemiology ; pathology ; Carcinoma, Squamous Cell ; epidemiology ; pathology ; China ; epidemiology ; Face ; Humans ; Incidence ; Mouth Mucosa ; Mouth Neoplasms ; epidemiology ; pathology ; Odontogenic Tumors ; Retrospective Studies ; Salivary Gland Neoplasms
9.Diagnostic accuracy and pitfalls in fine needle aspiration cytology of salivary glands: a study of 113 cases.
Bing-Jian LÜ ; Jia ZHU ; Li GAO ; Lei XIE ; Jing-Yao XU ; Mao-de LAI
Chinese Journal of Pathology 2005;34(11):706-710
OBJECTIVETo describe the fine needle aspiration cytology (FNAC) features of various salivary gland lesions and to analyze the respective diagnostic value and pitfalls.
METHODS113 FNAC specimens of salivary gland lesions were reviewed and correlated with clinical and histopathologic findings.
RESULTSThe FNAC diagnostic failure (2); non-neoplastic lesions (12); benign neoplasm (82) and malignant neoplasm (17). Cytologically, the distinction between cellular pleomorphic adenoma, adenoid cystic carcinoma and basal cell adenoma could be difficult due to their overlapping morphologic features. The cytologic patterns of primary lymphoepithelial carcinoma of the parotid were indistinguishable from those of metastatic nasopharyngeal undifferentiated carcinoma. The ultimate distinction relied on clinical correlation. The three inaccurately diagnosed cases of FNAC are, as follows: reactive lymphoid hyperplasia of lymph node mistaken as non-Hodgkin lymphoma, mucoepidermoid carcinoma diagnosed as "scanty atypical cells present" and primary lymphoepithelial carcinoma mistaken as benign lymphoepithelial lesion. On the basis of FNAC, 97.4% (110 /113) were correctly depicted as benign (95/96; 99.0%) or malignant (15/17; 88.2%). Furthermore, 90.3% (102 /113) (specificity = 91.9%; 102/111) were accurately diagnosed, including 91.7% (88/96) benign lesions (specificity = 92.6% ; 88/95) and 82.4% (14/17) malignant tumors (specificity = 87.5%; 14/16).
CONCLUSIONSFNAC is reliable in distinguishing benign and malignant salivary gland lesions. A specific cytologic diagnosis is often possible. On the other hand, due to the pitfalls in cytologic diagnosis of certain salivary gland tumors, tissue biopsy for histologic examination may be necessary.
Adenolymphoma ; pathology ; Adenoma ; pathology ; Adenoma, Pleomorphic ; pathology ; Adolescent ; Adult ; Aged ; Biopsy, Fine-Needle ; Carcinoma, Adenoid Cystic ; pathology ; Carcinoma, Mucoepidermoid ; pathology ; Carcinoma, Squamous Cell ; pathology ; Child ; Diagnosis, Differential ; Diagnostic Errors ; Female ; Humans ; Male ; Middle Aged ; Parotid Neoplasms ; pathology ; Retrospective Studies ; Salivary Gland Neoplasms ; pathology ; Salivary Glands ; pathology ; Submandibular Gland Neoplasms ; pathology