1.Primary Sebaceous Carcinoma of the Corneaoscleral Limbus With Pagetoid Recurrence.
Sang Jun PARK ; Won Ryang WEE ; Jin Hak LEE ; Mee Kum KIM
Korean Journal of Ophthalmology 2009;23(2):104-107
We report a sebaceous carcinoma confined to the corneoscleral limbus without involvement of the eyelid. A 60-year-old man, who showed multiple masses on the corneaoscleral limbus and limbal ulceration but with normal eyelids, underwent surgical en-bloc excision of the masses. Histopathologic examination revealed a sebaceous carcinoma. Three weeks after excision, multiple pagetoid recurrences were found along the bulbar conjunctiva 2 mm away from the limbus. After the application of topical mitomycin C, the pagetoid spread regressed completely. After a 2 year follow-up, no other local or systemic recurrences were observed. This report shows that the ulcerative mass which is confined to only the corneoscleral limbus may be a sebaceous carcinoma even without eyelid involvement. Topical mitomycin C may be effective for treating pagetoid spread of sebaceous carcinoma of limbal origin.
Adenocarcinoma, Sebaceous/*pathology/surgery
;
Biological Dressings
;
Diagnosis, Differential
;
Eye Neoplasms/*pathology/surgery
;
Follow-Up Studies
;
Humans
;
Limbus Corneae/*pathology
;
Male
;
Middle Aged
;
*Neoplasm Recurrence, Local
;
Ophthalmologic Surgical Procedures/methods
;
Sebaceous Gland Neoplasms/*pathology/surgery