1.Acute Generalized Exanthematous Pustulosis Due to Oral Use of Blue Dyes.
Osman SENER ; Osman KOSE ; Ozgur KARTAL ; Mukerrem SAFALI
The Korean Journal of Internal Medicine 2011;26(3):360-363
Acute generalized exanthematous pustulosis is a rare severe pustular cutaneous adverse reaction characterized by a rapid clinical course with typical histological findings. It is accompanied by fever and acute eruption of non-follicular pustules overlying erythrodermic skin. The causative agents are most frequently antibacterial drugs. We present a patient with acute generalized exanthematous pustulosis caused by methylene blue and indigotin dyes.
Acute Generalized Exanthematous Pustulosis/*chemically induced/drug therapy/pathology
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Administration, Oral
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Adrenal Cortex Hormones/therapeutic use
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Aged
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Biopsy
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Coloring Agents/administration & dosage/*adverse effects
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Humans
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Indoles/administration & dosage/*adverse effects
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Intradermal Tests
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Male
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Methylene Blue/administration & dosage/*adverse effects
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Skin/*drug effects/pathology
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Treatment Outcome