No abstract available.
Acneiform Eruptions*

Varioua articles have been reported that extemal contactants were the cause Acne venenata. The daily use of cosmetics are tbe cause of Acne minor in adult wamen. To distinguish this from other type of Acne venenata due to extemal contactants Kligman had coined the term Acne cosmetica, which is a low grade persistant acneiform eruption with occasional papulopustulea in adult women. The authors have tested a wide range of available cosmetics(Total twenty including four kinds of cold cream species, two of cleansing cream species, three of nutrient cream species, six of lotion species, three of foundation make up species and two of foreign cosmetics) using the rabbit ear assay recently popularized by Kligman in order to evaluate comedogenic effects of various Korean ccsmetics. The results a.re as follows. 1. Among these twenty facial cosmetics, We observed no comedogenccicy in two facial cosmetics, mildly comcdogenecity in twelve facial cosmetics, moderately comedo- genecity in four facial cosmetics and severe comedogenecity in two facial cosmetics. 2. Histologic gradings were paralleled the findings of tbe naked eye in up to 65% 3. There were significant differences on comedogenecity between Korean cosmetics and foreign cosmetics which used by Kligman. 4. There were no significant diffrences between cold cream species, cleansing cream species. nutrient, cream species, lotion species and foundation make up species. 5, There were various differences among twenty kinds of every cosmetic specie.
Acne Vulgaris ; Acneiform Eruptions ; Adult ; Ear ; Female ; Humans ; Numismatics

No abstract available.
Acneiform Eruptions ; Bevacizumab

The occurrence of a new skin disorder at t.he site of another unrelated and already healed skin disease is called an isotopic response. This was defined by Wolf et al in 1995. The preceding diseases are mostly herpes zosters and various other diseases, such as carcinoma, granuloma annulare can follow. There has been only one report of an acneiform eruption occurring on the healed site of herpes zoster. We report, herein, a case of acneiform eruption that had developed on a site previously affecled by herpes zoster, which is thought to be an isotopic response.
Acne Vulgaris ; Acneiform Eruptions* ; Granuloma Annulare ; Herpes Zoster* ; Skin ; Skin Diseases ; Wolves

BACKGROUND: Steroid acne is a folliculitis that can result from a systemic or topical administration of steroid and has been described as showing similar clinical pictures to Malassezia folliculitis, but there have been few reports about the incidence of Malassezia in steroid acne and other acneiform eruptions. OBJECTIVE: Our purpose was to describe the incidences of Malassezia in acneiform eruptions and to discuss about the relationship between clinical steroid acne and Malassezia folliculitis. METHODS: The history, clinical features, direct microscopy, histopathological analysis, and therapeutic results of 125 cases with steroid acne or other acneiform eruptions were described and compared. RESULTS: Over 80% of patients with acneiform eruption receiving systemic steroid revealed significant numbers of Malassezia in the lesional follicle. CONCLUSION: Steroid acne and other acneiform eruptions showing discrete follicular papules and/or pustules localized to the upper trunk or acneiform facial skin lesions associated with multiple acneiform lesions on the body in the summer period should be suspected as Malassezia folliculitis.
Acne Vulgaris* ; Acneiform Eruptions* ; Administration, Topical ; Folliculitis ; Humans ; Incidence* ; Malassezia* ; Microscopy ; Skin

BACKGROUND: Steroid acne have similar clinical manifestations with Malassezia folliculitis, so it is not easy to distinguish between these disease entities clinically. And there have been few reports about them and the therapeutic efficacy of antifungal agent for steroid acne. OBJECTIVE: We aimed to find out different points clinically between steroid-using acneiform eruption group and the group without use, and describe the results of direct-microscopic examinations and establish the relationships between therapeutic responses to oral antifungal agent and some variables like use of corticosteroids, grade of direct-microscopically positive score. METHODS: With 91 patients according to the protocol prepared, we described characteristics of the lesions, sites, and distributions, use of corticosteroids, then examined Malassezia spores with 10% KOH/Parker blue black ink mount from patient's skin lesions. And finally we compared the reponses to antifungal agent. For objective evaluation we used direct microscopic grading method to count spores introduced by Jacinto-Jamora et al. RESULTS: In both groups with and without use of corticosteroids, most had characteristics of papules and pustules, symmetric distributions except the patients using topical corticosteroids. In all positive groups, there was no significant difference in therapeutic responses regardless of the previous use of corticosteroids. Interestingly therapeutic response rate of (1+) group to itraconazole are similar with that of higher scoring groups. CONCLUSION: We suggest that not in a tropical area like Korea, direct-microscopically low score ((1+) or (2+)) and even negatives with typical manifestations of Malassezia folliculitis has a clinical significance and both steroid acne and Malassezia folliculitis may be one spectrum of the same disease.
Acne Vulgaris* ; Acneiform Eruptions ; Adrenal Cortex Hormones ; Folliculitis* ; Humans ; Ink ; Itraconazole ; Korea ; Malassezia* ; Skin ; Spores

BACKGROUND: The representative organism isolated from acne lesion is Propionibacterium acnes (P. acnes), but other organisms, such as Staphylococcus epidermidis (S. epidermidis), have also been isolated. These organisms play an important role in the inflammatory process, therefore, we usually treat the inflammatory acne with antibiotics. However, long term use of antibiotics may result in development of resistant strains and treatment failure. In these cases, antibiotic susceptibility test may be helpful. OBJECTIVE: The purpose of this study was to investigate microorganisms isolated from acne and their antibiotic susceptibility METHOD: We examined the species of bacteria aerobically and anaerobically isolated from 41 patients (38 acne patients and 3 acneiform eruption patients) and determined the antimicrobial susceptibilities of P. acnes and S. epidermidis. For P. acnes, we measured the minimal inhibitory concentration(MIC) of tetracycline by using E test. RESULT: Among the bacteria isolated, P. acnes (18 patients) was the most common, followed by S. epidermidis (14 patients). The MICs of tetracycline ranged from 0.016 to 0.380 microgram/ml, and 94.1% were inhibited by < or = 0.094 microgram/ml of tetracycline. The tetracycline MICs of P. acnes isolates were significantly lower when isolates came from patients whose acne duration was less than 2 years. The isolation rate of P. acnes was significantly higher in pustule lesions compared to non-pustule lesions. In antibiotic susceptibility test for S. epidermidis, the resistance rate of ofloxacin, erythromycin, clindamycin and tetracycline was 14.3%, 35.7%, 21.4% and 50.0% respectively. CONCLUSION: We confirmed that representative organisms isolated from acne lesions were P. acnes and S. epidermidis, and that the ranges of tetracycline MICs for P. acnes were low, thus suggesting that the appearance of resistant strains of P. acnes is not yet common. On the other hand, the resistance rate of S. epidermidis was relatively high. Therefore when we use antibiotics for acne patients, we should keep in mind that the appearance of resistant strain is possible and antibiotic susceptibility should be checked.
Acne Vulgaris* ; Acneiform Eruptions ; Anti-Bacterial Agents ; Bacteria ; Clindamycin ; Erythromycin ; Hand ; Humans ; Ofloxacin ; Propionibacterium acnes ; Staphylococcus epidermidis ; Tetracycline ; Treatment Failure

BACKGROUND: Acne is a common follicular inflammatory dermatoses affecting sebaceous glands. It has been known that Malassezia, the lipophilic normal human skin flora, contribute to the development of acne lesion, but the detailed clinical features and effective treatment methods are lacking. OBJECTIVE: In order to elucidate clinical features and efficacy of antifungal treatment in acne associated with Malassezia, we conducted a prospective clinical study with mild to moderate acne patients. METHODS: Twenty eight patients (13 men and 15 women, mean age 19.1+/-4.4 years) with the acneiform eruptions on their face and upper trunk who showed Malassezia from comedo on the KOH/Parker ink examination (spore load 3+ over) were included in this study. Oral itraconazole, 200mg/day, was given at the beginning of treatment for one week. Clinical assessment for the acne lesions(Cunliffe score by Leeds technique and Global acne grading system) and mycological examination were done at the beginning, 2 and 4 weeks of treatment. RESULTS: Acne associated with Malassezia showed polymorphous eruption composed of open and closed comedo, inflammatory papules and pustules. Acneiform eruptions were found on the forehead(67%), cheek(64%), submental(60%) and temple area of the face. Among the patients, seborrhea(21%) and seborrheic dermatitis(14%) were accompanied. The acneiform eruption was aggravated during the summer season(18%). Systemic corticosteroids(14%) and menstruation(27% in women) were also mentioned as the aggravating factors. Systemic itraconazole significantly improved acne lesions from 2 weeks after treatment. CONCLUSION: The results imply that Malassezia should be examined in patients with mild to moderate acne on the face and upper trunk, simultaneously. Use of anti-Malassezia agent such as itraconazole can be considered as an initial treatment in those patients.
Acne Vulgaris* ; Acneiform Eruptions ; Female ; Humans ; Ink ; Itraconazole ; Malassezia* ; Male ; Prospective Studies ; Sebaceous Glands ; Skin ; Skin Diseases ; Yeasts*

Chloracne is a refractory acneiform eruption due to halogenated polyaromatic compound(eg. dioxin, dibenzofurans, polychlorinated biphenyls, etc.). 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin, a kind of dioxin isomer, contained in the Agent Orange which was used for defoliating agent during Vietnam war. It is characterized by recalcitrant comedones and cyst predominantly in the malar and postauricular area. Lesions of the penis and scrotum are also relatively frequent. The key pathological feature is the non-inflammatory keratinization of pilosebaceous unit. The meibomian glands are typically affected. Xerosis, conjunctivitis, pigmentation, follicular hyperkeratosis, actinic elastosis are occasionally associated with chloracne. We report a case of typical chloracne due to exposure to defoliating agent during Vietnam war in a 54-year-old-man who shows typical clinical and histopathological features.
Acneiform Eruptions ; Actins ; Chloracne* ; Citrus sinensis ; Conjunctivitis ; Male ; Meibomian Glands ; Penis ; Pigmentation ; Polychlorinated Biphenyls ; Scrotum ; Vietnam*

BACKGROUND: Fractional photothermolysis makes thousands of minute areas called microthermal treatment zones on the skin surface and transmits thermal injury to facilitate heat shock protein formation around the dermis. Potential side effects include acneiform eruption, herpes simplex virus outbreak, erythema, and post-inflammatory hyperpigmentation. OBJECTIVE: To investigate and compare the changes in the skin of Asian patients after two different fractional photothermolysis systems (FPS) on a split face. METHODS: A half-split face study was performed with 10,600 nm carbon dioxide FPS on the left and 1,550 nm erbium-doped FPS on the right side of the face. Only one session of laser irradiation and several biophysical measurements were done. RESULTS: Although both FPS proved to be effective in treating acne scar and wrinkle patients, a slightly higher satisfaction rating was seen with the 10,600 nm FPS treatment. Both types of FPS showed a significant increase in transepidermal water loss which decreased gradually after treatment and returned to pre-treatment level after 1 week. A decreased reviscometer score was sustained for a longer period in wrinkle areas treated with 10,600 nm FPS. CONCLUSION: Even though the changes in skin varied according to different FPS wave-length, adverse outcomes, such as increased erythema and TEWL were entirely subdued within 3 months of treatment.
Acne Vulgaris ; Acneiform Eruptions ; Asian Continental Ancestry Group ; Carbon Dioxide ; Cicatrix ; Dermis ; Erythema ; Heat-Shock Proteins ; Humans ; Methylmethacrylates ; Polystyrenes ; Simplexvirus ; Skin ; Water Loss, Insensible