1.Two symmetrical unsaturated acids isolated from Viscum album.
Duo CAO ; Li-Qing WANG ; Xiao-Min HAN ; Hui-Rui GUAN ; Meng LEI ; Ya-Hui WEI ; Liang CHENG ; Pei-Ming YANG ; Zheng-Liang SUN ; Wen GAO ; Jia-Kun DAI
Chinese Journal of Natural Medicines (English Ed.) 2019;17(2):145-148
In the present study, two new acetylene conjugate compounds, dibutyl (2Z, 6Z)-octa-2, 6-dien-4-yne dioate (1), and dibutyl (2E, 6E)- octa-2, 6-dien-4-yne dioate (2), were isolated from the dry stem leaves of Viscum album, along with nine known compounds (3 - 11). Their structures were confirmed on the basis of spectroscopic data. Compounds 1 and 8 showed antioxidant activity against xanthine oxidase (XOD) and 1,1-diphenyl-2-picrylhydrazyl radical 2,2-diphenyl-1-(2,4,6-trinitrophenyl) hydroxyl (DPPH), with the IC of 1.22 and 1.33 μmol·L, and the SC of 4.34 and 8.22 μmol·L, respectively.
Acetylene
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chemistry
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Antioxidants
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chemistry
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pharmacology
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Biphenyl Compounds
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chemistry
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Molecular Structure
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Picrates
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chemistry
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Plant Extracts
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chemistry
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pharmacology
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Plant Leaves
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chemistry
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Viscum album
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chemistry
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Xanthine Oxidase
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chemistry