3.Therapeutic intervention against deacclimatization to high altitude.
Yin-Hu WANG ; Qi-Quan ZHOU ; Sheng-Hong YANG ; Yan WANG ; Bin LI ; Chao-Liang LONG ; Hai WANG
Chinese Journal of Applied Physiology 2013;29(6):512-517
The incidence of deacclimatization to high altitude syndrome (DAHAS) prevailed up to 80% in highland troops, and 100% in manual workers, and severe DAHAS could significantly affects patients' health, work and life. So it is imperative to develop effective prevention and treatment measures for DAHAS. The present review analyzes effective prophylactic and therapeutic measures against DAHAS, implemented at our hospital.
Acclimatization
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Altitude
;
Altitude Sickness
;
prevention & control
;
therapy
;
Humans
4.The deacclimatization symptom scores of 159 youth returning to the same plain from different plateau.
Yin-Hu WANG ; Yan WANG ; Sheng-Hong YANG ; Bin LI ; Qi-Quan ZHOU
Chinese Journal of Applied Physiology 2014;30(1):18-21
OBJECTIVETo analysis deacclimatization symptom scores of 159 youth from Karakoram and Tibet Ali area, and provide the basis for the development of relevant prevention and control measures.
METHODSUsing the method of epidemiological symptoms questionnaire, 18 symptoms of 190 youth who returned to the plain area from the different plateau were investigated. The symptom scores of different altitude, age, the time of staying, different units, continuous or intermittent stage and education were surveyed.
RESULTSDeacclimatization symptom scores among 5,000 meter groups were significantly higher than those of 4,300 meter and 3,700 meter group (P < 0.05, P < 0.01). There was no significant difference between the 4,300 meter group and the 3,700 meter group (P > 0.05). There were significant differences among the stayed personnel (different age, position, unit, education, time, continuous or intermittent) (P < 0.01). There was significant difference between the continuous defended the group and intermittent group (P < 0.01).
CONCLUSIONDeacclimatization symptom scores were related to the plateau exposure time, altitude, workload, plateau continued exposure. The older, the longer exposure, the higher altitude, the greater workload at plateau were showed higher deacclimatization symptom score.
Acclimatization ; Altitude ; Altitude Sickness ; physiopathology ; Humans ; Surveys and Questionnaires ; Tibet
6.Factors affecting pulmonary arterial pressure in response to high-altitude hypoxic stress.
Zhen ZHOU ; Feng TANG ; Ri-Li GE
Acta Physiologica Sinica 2023;75(1):130-136
The alteration of pulmonary artery pressure is an important physiological indicator to reflect the organism's adaptation to acclimatization or the pathological injury in response to high-altitude hypoxic environment. The effects of hypoxic stress at different altitudes for different time on pulmonary artery pressure are different. There are many factors involved in the changes of pulmonary artery pressure, such as the contraction of pulmonary arterial smooth muscle, hemodynamic changes, abnormal regulation of vascular activity and abnormal changes of cardiopulmonary function. Understanding of the regulatory factors of pulmonary artery pressure in hypoxic environment is crucial in clarifying the relevant mechanisms of hypoxic adaptation, acclimatization, prevention, diagnosis, treatment and prognosis of acute and chronic high-altitude diseases. In recent years, great progress has been made in the study regarding the factors affecting pulmonary artery pressure in response to high-altitude hypoxic stress. In this review, we discuss the regulatory factors and intervention measures of pulmonary arterial hypertension induced by hypoxia from the aspects of hemodynamics of circulatory system, vasoactive state and changes of cardiopulmonary function.
Humans
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Altitude
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Arterial Pressure
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Acclimatization
;
Hypoxia
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Muscle, Smooth
7.Factors affecting heat-related diseases in outdoor workers exposed to extreme heat.
Jungsun PARK ; Yangho KIM ; Inbo OH
Annals of Occupational and Environmental Medicine 2017;29(1):30-
BACKGROUND: The objectives of the present study are to: (i) evaluate the effect of environmental and metabolic heat on heat-related illnesses in outdoor workers; and (ii) evaluate the effect of personal factors, including heat acclimation, on the risk of heat-related illnesses in outdoor workers. METHODS: We identified 47 cases of illnesses from exposure to environmental heat in outdoor workers in Korea from 2010 to 2014, based on review of workers' compensation data. We also obtained the information on location, time, and work environment of each heat-related illness. RESULTS: Our major results are that 29 cases (61.7%) occurred during a heat wave. Forty five cases (95.7%) occurred when the maximum estimated WBGT (WBGTmax) was equal to or greater than the case specific threshold value which was determined by acclimatization and metabolic rate. Twenty two cases (46.8%) were not acclimated to the heat. Thirty-seven cases (78.7%) occurred after tropical night (temperature above 25 °C), during which many people may find it hard to sleep. CONCLUSION: Personal risk factors such as heat acclimation as well as environmental factors and high metabolic rate during work are the major determinants of heat-related illnesses.
Acclimatization
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Extreme Heat*
;
Hot Temperature
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Humans
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Infrared Rays
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Korea
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Risk Factors
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Workers' Compensation
8.Ecological evaluation of suitable area for production of Phellodendron amurense based on TCMGIS- I.
Feng-Mei SUO ; Shi-Lin CHEN ; Zhao ZHANG ; Cai-Xiang XIE
China Journal of Chinese Materia Medica 2008;33(13):1536-1539
The TCMGIS- I (Suitability evaluation geographic information system of traditional Chinese medicine producing area ) was developed and used to analyze the appropriate producing area of Phellodendron amurense in China. Taoshan county of Heilongjiang province, one of the main producing areas of the geo-authentic crude drug, was selected as the analytical basal place. The results show that besides traditional producing area in Taoshan county of Heilongjiang province, 131 counties of the provinces of Heilongjiang, Jilin, Liaoning and Innermongolia are also alternative areas according to the eco-soil condition that the medicinal plants needed, and the sum area are 567 989. 3 m2, the results also indicate some condign regions in Innermongolia municipality. The system is much valuable to the division of adaptive area, introduction and acclimatization of medicinal materials.
Acclimatization
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China
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Ecosystem
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Geographic Information Systems
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Medicine, Chinese Traditional
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Phellodendron
;
growth & development
;
physiology
9.Newest research progress in hypoxia genetic adaptation to high altitude.
Journal of Biomedical Engineering 2010;27(3):711-715
The genetic adaptation of Plateau residents to hypoxia of low-pressure has been the hot spot for study. In terms of physiology, the adaptation involves the regulation responses of blood vessels, the changes in blood cells, antioxidant capacity and energy metabolism, as well as the hypoxia-induced changes in nuclear transcription. Physiological adaptation is heritable, so people who have already adapted themselves to high altitude are bound to be different, in regard to gene level, from the crowd who have not yet adapted themselves to high altitude environment. For this reason, researchers have studied a great deal of gene related-enzymes, the receptors, polypeptide, as well as transcription factors in body, and they found a number of the DNA polymorphism sites in the people who have adapted themsevles to high altitude being different from those in the people who do not get acclimatized. In this paper is reviewed the newest advance in research of these gene polymorphisms. The data could serve as references for further study of hypoxia genetic adaptation to high altitude.
Acclimatization
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genetics
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Adaptation, Physiological
;
genetics
;
Altitude
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Humans
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Hypoxia
;
genetics
;
Polymorphism, Genetic
;
genetics
10.Study on comparative-physiology of some endocrinal activities on cold exposure and cold acclimation in rats and chicks.
Shi-Ze LI ; Yu-Ying YANG ; Huan-Min YANG
Chinese Journal of Applied Physiology 2008;24(1):23-103
Acclimatization
;
physiology
;
Animals
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Animals, Newborn
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Chickens
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Cold Temperature
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Endocrine Glands
;
physiology
;
Female
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Male
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Rats
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Rats, Wistar