Objective:To explore the improvement effect of positive emotional support combined with education mode based on animation demonstration on treatment compliance in children with bronchial asthma (BA) so as to provide guidance for clinical nursing of BA children.Methods:The quasi-experiment research scheme was adopted. The children with BA admitted to the First Affiliated Hospital of Xinjiang Medical University were enrolled as the research objects by convenience sampling method. Grouped according to admission time, 52 children with BA were treated as the control group from January 2020 to June 2021, and 52 children with BA were treated as the experimental group from July 2021 to June 2022. The control group received routine nursing care, while the experimental group received positive emotional support in addition to routine nursing care, combined with an animated demonstration health education model for intervention.According to 6 months of follow-up, changes of treatment compatibility, asthma control, psychological state and quality of life after intervention in the two groups were observed.Results:In control group, there were 31 boys and 21 girls, with age of (9.95 ± 1.57) years. In experimental group, there were 35 boys and 17 girls, with age of (9.46 ± 1.02) years. After intervention, the treatment compatibility of the experimental group was 96.15% (50/52), which was higher than 80.77% (42/52) of the control group, and the difference was statistically significant ( χ2=6.03, P<0.05); the asthma control rate in the experimental group was 94.23% (49/52), which was higher than the control group′s 75.00% (39/52), and the difference was statistically significant ( χ2=7.39, P<0.05); the scores of psychological state (psychoticism, neuroticism, dissembling or lying) in experimental group were 42.18 ± 4.21, 49.23 ± 4.66 and 48.63 ± 4.26, higher than those in control group 38.22 ± 4.32, 46.36 ± 4.87, 44.33 ± 3.47, the differences were statistically significant ( t=4.73, 3.07, 5.64, all P<0.05), The score of introversion-extroversion of the observation group was 56.86 ± 5.58, lower than the control group′s 59.66 ± 5.17, and the difference was statistically significant ( t=2.65, P<0.05). The total score of the scale and the scores of symptoms, activities and emotions in experimental group were 114.71 ± 18.33, 51.36 ± 7.88, 24.66 ± 4.36 and 38.69 ± 5.29, higher than those in control group 96.42 ± 14.34, 43.26 ± 7.21, 22.28 ± 4.27, 30.88 ± 5.84, the difference was statistically significant ( t values were 2.81-7.15, all P<0.05). Conclusions:The application of positive emotional support combined with education mode based on animation demonstration in the clinical nursing of BA children can improve treatment compliance and asthma control rate, effectively improve quality of life and psychological state.