1.Effects of vasopressin and adrenaline on cerebral resuscitation in rats undergone cardiopulmonary resuscitation
Chinese Journal of Emergency Medicine 2011;20(3):277-280
Objective To compare the effects of vasopressin and adrenaline on cerebral resuscitation in rats. Method Sixty male SD rats were used to set the animal model of cardiac arrest and were randomly (random number) divided into 4 groups (n = 15/group): sham operation group (sham-gro), negative control group (neg-gro), vasopressin group (vas-gro) and adrenaline group (adr-gro). Blood pressure was recorded, and brain tissue samples were obtained. Results There was no significant difference in the recovery rate between vas-gro and adr-gro 30 min after resuscitation (P <0.05). The mean blood pressure in vasgro was higher than that in adr-gro within 30 min (1,2, 5, 10, 20, 30 min) after restoration of spontaneous circulation. The measured MDA, SOD and GSH were significantly different (P < 0.05) between each two groups among vas-gro, sham-gro and adr-gro. Conclusions The recovery rate was similar between vasopressin group and adrenaline group during cardiopulmonary resuscitation in rats. However, vasopressin can to maintain the mean arterial pressure at a higher level after resuscitation, which can the increase the cerebral perfusion and reduce brain cell damage.
2.Effects of Maca on kidney mitochondrial respiratory function and anti-aging capabilities in aged rats after exhausted exercise
Chinese Journal of Tissue Engineering Research 2016;20(18):2711-2716
BACKGROUND: Studies have shown that Maca can enhance immune cel function, improve mitochondrial respiratory chain enzymes, and play a role in anti-oxidation and anti-aging.
OBJECTIVE: To observe Maca effects on kidney mitochondrial respiratory function and anti-aging capabilities in elderly rats after exhausted exercise.
METHODS: 10-month-old elderly rats were intragastrical y administrated Maca powder 5 g/kg, once a day, and did treadmil exercise, 5 days in a week. Rats were randomly divided into control group, Maca group and training group and Maca+training group. At 6 weeks after training, rats in each group did exhausted exercise (35 m/min), and immediately received intraperitoneal injection of 2% sodium pentobarbital. The kidney was obtained, and mitochondria were extracted by differential centrifugation. A spectrophotometer was used to measure mitochondrial respiratory chain activity.
RESULTS AND CONCLUSION: (1) Mitochondrial respiratory chain enzyme and antioxidant enzyme activity: mitochondrial respiratory chain enzyme I-III, superoxide dismutase and glutathione peroxidase activities were higher in the Maca+training group than in the control group, Maca group and training group (P < 0.05 or P < 0.01), but malondialdehyde content was lower (P < 0.05 or P < 0.01). (2) Results suggested that the combination of supplement Maca and incremental exercise can improve mitochondrial respiratory function and delay aging in the kidney of aged rats after exhausted exercise. Moreover, supplemented Maca and incremental exercise have a synergistic effect.
3.Characteristics of medical and health literature novelty assessment in institutions of armed forces, its problems and solutions
Chinese Journal of Medical Library and Information Science 2014;(5):59-61
The characteristics of medical and health literature novel assessment in institutions of armed forces were described from the secrecy of projects for literature novelty assessment , the limitations of consignee institution , and the non-profitability of literature novelty assessment agency .The major problems of medical and health literature novel assessment in institutions of armed forces were elaborated in terms of the literacy, instability, competency and knowledge limitation of literature novel assessment staff with suggestions put forward for their solution such as strengthening the construction of talent team, joint development and sharing of resources.
4.Application of medical signal processing based on theory and method of chaos
International Journal of Biomedical Engineering 2006;0(02):-
Reviewing the theory of chaos in the field of nonlinear dynamics, this paper summarized theory of chaos and its applications in medical signal processing including electroencephalogram(EEG) signal?electrocardiogram(ECG) signal?electromyogram(EMG) signal, etc. The foreground is reviewed to advance the study and application of nonlinear dynamics theory in biomedical engineering.
5.Effects of Hormone Replacement Therapy and Sport Walk with Weight on Serum Lipid and Bone Mineral Density in Postmenopausal Women
Chinese Journal of Rehabilitation Theory and Practice 2008;14(10):974-976
Objective To explore the effects of estrogen,sport walking with weight and estrogen plus sport walk on serum lipid,bone metabolism and bone mineral density(BMD) in postmenopausal women.Methods 52 postmenopausal women were divided into the hormone replacement therapy(HRT) group(n=12),sport walking with weight group(Sp group,n=14),HRT + Sp group(n=12) and control group(n=14).HRT group took compound nylestriol,Sp group took sport walking with 5 kg weight and exercise intensity was from 60% to 80% VO2max,HRT+Sp group received two treatments as HRT group and Sp group.The experimental duration consisted of six months.Results The total cholesterol(TC),TC/high density lipoprotein cholesterol(HDL-C),alkaline phosphatase(APL) and urine calcium(Ca)/creatinine(Cr) were markedly lower in three experimental groups than the control group and before experiment(P<0.05 or P<0.01),HDL-C in Sp and HRT+Sp groups were markedly higher than the control group and before experiment(P<0.05),BMD of spine(L2~L4) and left trochanter in three experimental groups were markedly higher than the control group(P<0.01) and before experiment(P<0.0).Conclusion Both estrogen replacement therapy and sport walking with weight effectively improve serum lipid,prevent and reverse osteoporosis induced by menopause in women.
7.Long-term outcomes of the respiratory and nervous system after bronchopulmonary dysplasia in premature infant
International Journal of Pediatrics 2016;43(7):548-551,556
Bronchopulmonary dysplasia (BPD) is a severe complication of preterm birth,especially in those with very low birth weight or extremely low birth weight.The incidence of BPD increased with more survival of very preterm infants.Neonates with BPD are more oxygen-dependent and require prolonged mechanical ventilation.Respiratory and neurological outcomes in the childhood and even early adulthood,including pulmonary symptoms,re-admittance rate,pulmonary hypertension and dysfunction,will be adversely influenced.Meanwhile,BPD patients will develop more problems in cognition,education and behavior.
8.Manifestation and therapies of EGFRI-induced dermatological toxicities
Chinese Journal of Clinical Oncology 2017;44(13):673-676
In the past decades, the advent of molecular targeted agents has been a considerable breakthrough for cancer patients, ex-cept for traditional operation, chemotherapy, and radiotherapy. As a novel therapeutic method, molecular targeting treatment is im-portant in the field of medical oncology, in which epidermal growth factor receptor inhibitors (EGFRIs) have been widely used as target-ed agents. Dermatological toxicities are the common side effects associated with the EGFRIs. Diarrhea, weakness, and pneumonia can be observed. EGFRI-induced dermatological toxicities may disrupt the health-related quality of life and cause anticancer treatment dose adjustments or discontinuance. The dermatological toxicities mainly involve rash acneiform, pruritus, xerosis, paronychia, hair change, and skin hypersensitivity. Treatment recommendations from guidelines include antibiotics, corticosteroids, and antihista-mines, but their clinical therapeutic efficacy have not been proven. Therefore, oncologists and dermatologists are investigating effec-tive medication. This article reviews the advances in the study of the clinical manifestations and drug therapies of EGFRI-induced der-matological toxicities to provide reference for clinical practitioners.
9.New Perspective of Traditional Chinese Medicine Study-A Literature Review on Metaphor in Traditional Chinese Medicine
World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(6):1411-1416
Traditional Chinese medicine (TCM), which has become the representative of traditional medicine and cul-ture, has caught the attention among people from various fields. Metaphor thinking, which exists in TCM language, has attracted multidisciplinary experts and scholars from the field of TCM study, linguistics and philosophy. This ar-ticle was aimed to collect and analyze previous study results on TCM metaphor, in order to find out the study value and explanation methods on TCM language and TCM theories. At present, there were metaphor studies in TCM in-cluding macroscopic studies based on rhetoric and cognitive linguistics, medium-scopic researches on basic TCM theories, etiology and pathogenesis, as well as microscopic studies of TCM classics language and terminology. Sys-tematic multidisciplinary studies of metaphor in TCM based on corpora will be the future study direction.
10.With Chinese medicine psychology after the disaster the psychology intervenes
Chinese Medical Ethics 1995;0(03):-
This article analyzes the Chinese medicine psychology the principle,elaborated after earthquake disaster,people's main psychological feature,and proposed the Chinese medicine psychology intervention method.