1.Characteristics of medical and health literature novelty assessment in institutions of armed forces, its problems and solutions
Chinese Journal of Medical Library and Information Science 2014;(5):59-61
The characteristics of medical and health literature novel assessment in institutions of armed forces were described from the secrecy of projects for literature novelty assessment , the limitations of consignee institution , and the non-profitability of literature novelty assessment agency .The major problems of medical and health literature novel assessment in institutions of armed forces were elaborated in terms of the literacy, instability, competency and knowledge limitation of literature novel assessment staff with suggestions put forward for their solution such as strengthening the construction of talent team, joint development and sharing of resources.
2.Application of medical signal processing based on theory and method of chaos
International Journal of Biomedical Engineering 2006;0(02):-
Reviewing the theory of chaos in the field of nonlinear dynamics, this paper summarized theory of chaos and its applications in medical signal processing including electroencephalogram(EEG) signal?electrocardiogram(ECG) signal?electromyogram(EMG) signal, etc. The foreground is reviewed to advance the study and application of nonlinear dynamics theory in biomedical engineering.
3.Effects of vasopressin and adrenaline on cerebral resuscitation in rats undergone cardiopulmonary resuscitation
Chinese Journal of Emergency Medicine 2011;20(3):277-280
Objective To compare the effects of vasopressin and adrenaline on cerebral resuscitation in rats. Method Sixty male SD rats were used to set the animal model of cardiac arrest and were randomly (random number) divided into 4 groups (n = 15/group): sham operation group (sham-gro), negative control group (neg-gro), vasopressin group (vas-gro) and adrenaline group (adr-gro). Blood pressure was recorded, and brain tissue samples were obtained. Results There was no significant difference in the recovery rate between vas-gro and adr-gro 30 min after resuscitation (P <0.05). The mean blood pressure in vasgro was higher than that in adr-gro within 30 min (1,2, 5, 10, 20, 30 min) after restoration of spontaneous circulation. The measured MDA, SOD and GSH were significantly different (P < 0.05) between each two groups among vas-gro, sham-gro and adr-gro. Conclusions The recovery rate was similar between vasopressin group and adrenaline group during cardiopulmonary resuscitation in rats. However, vasopressin can to maintain the mean arterial pressure at a higher level after resuscitation, which can the increase the cerebral perfusion and reduce brain cell damage.
4.Effects of Maca on kidney mitochondrial respiratory function and anti-aging capabilities in aged rats after exhausted exercise
Chinese Journal of Tissue Engineering Research 2016;20(18):2711-2716
BACKGROUND: Studies have shown that Maca can enhance immune cel function, improve mitochondrial respiratory chain enzymes, and play a role in anti-oxidation and anti-aging.
OBJECTIVE: To observe Maca effects on kidney mitochondrial respiratory function and anti-aging capabilities in elderly rats after exhausted exercise.
METHODS: 10-month-old elderly rats were intragastrical y administrated Maca powder 5 g/kg, once a day, and did treadmil exercise, 5 days in a week. Rats were randomly divided into control group, Maca group and training group and Maca+training group. At 6 weeks after training, rats in each group did exhausted exercise (35 m/min), and immediately received intraperitoneal injection of 2% sodium pentobarbital. The kidney was obtained, and mitochondria were extracted by differential centrifugation. A spectrophotometer was used to measure mitochondrial respiratory chain activity.
RESULTS AND CONCLUSION: (1) Mitochondrial respiratory chain enzyme and antioxidant enzyme activity: mitochondrial respiratory chain enzyme I-III, superoxide dismutase and glutathione peroxidase activities were higher in the Maca+training group than in the control group, Maca group and training group (P < 0.05 or P < 0.01), but malondialdehyde content was lower (P < 0.05 or P < 0.01). (2) Results suggested that the combination of supplement Maca and incremental exercise can improve mitochondrial respiratory function and delay aging in the kidney of aged rats after exhausted exercise. Moreover, supplemented Maca and incremental exercise have a synergistic effect.
5.Effects of Hormone Replacement Therapy and Sport Walk with Weight on Serum Lipid and Bone Mineral Density in Postmenopausal Women
Chinese Journal of Rehabilitation Theory and Practice 2008;14(10):974-976
Objective To explore the effects of estrogen,sport walking with weight and estrogen plus sport walk on serum lipid,bone metabolism and bone mineral density(BMD) in postmenopausal women.Methods 52 postmenopausal women were divided into the hormone replacement therapy(HRT) group(n=12),sport walking with weight group(Sp group,n=14),HRT + Sp group(n=12) and control group(n=14).HRT group took compound nylestriol,Sp group took sport walking with 5 kg weight and exercise intensity was from 60% to 80% VO2max,HRT+Sp group received two treatments as HRT group and Sp group.The experimental duration consisted of six months.Results The total cholesterol(TC),TC/high density lipoprotein cholesterol(HDL-C),alkaline phosphatase(APL) and urine calcium(Ca)/creatinine(Cr) were markedly lower in three experimental groups than the control group and before experiment(P<0.05 or P<0.01),HDL-C in Sp and HRT+Sp groups were markedly higher than the control group and before experiment(P<0.05),BMD of spine(L2~L4) and left trochanter in three experimental groups were markedly higher than the control group(P<0.01) and before experiment(P<0.0).Conclusion Both estrogen replacement therapy and sport walking with weight effectively improve serum lipid,prevent and reverse osteoporosis induced by menopause in women.
6.The comparative analysis and bias evaluation on the results of serum CK,AST and LDH between two different kinds of biochemical analysis system
International Journal of Laboratory Medicine 2015;(14):2031-2033
Objective To discuss the comparability and bias evaluation on the results of serum creatine kinase (CK ) ,aspartate aminotransferase (AST) ,lactate dehydrogenase (LDH) inspection results between the two different kinds of biochemical analysis system .Methods The control quality materials with two concentration were detected respectively for degree of precision ,and the assessment standard was from manufacturer introductions and laboratory setting .Then in accordance with American Clinical and Laboratory Standard Institute(CLSI) document EP9‐A2 ,100 patients serum CK、AST、LDH were detected .Afterwards the relative bias(SE% ) was calculated ,and the comparative analysis bias evaluation was judged according to the half of CLIA′88 allowed total error .Results The variable coefficients mainly conformed to the requirements ,and the experimental results were reliable .The oth‐ers mainly lower than the acceptable limit besides SE% for LDH higher than it .Conclusion It is necessary to execute comparative analysis and bias evaluation to ensure the accuracy and comparability if the same item is detected in two analysis system .
7.The feasibility and effectiveness of the interspincterotomy combined with PPH in the treatment of severe mixed hemorrhoids and anal fissure
Chinese Journal of Primary Medicine and Pharmacy 2015;(19):2990-2992
Objective To explore the feasibility and effectiveness of the interspincterotomy combined with PPH in the treatment of severe mixed hemorrhoids and anal fissure.Methods 116 cases of glioma patients with post-operative residual lesions were treated.The observation group of 58 patients were treated with internal sphincterotomy combined with PPH resection,while 58 cases in the control group were treated by traditional external dissection and internal ligation plus resection of anal fissure.The efficacy and safety of treatment of the two groups of patients were evaluated.Results The operation time,hospitalization time,healing time,postoperative curative effect evaluation score of the observation group were (22.5 ±5.3)min,(2.1 ±0.9)d,(9.6 ±2.1)d and (9.8 ±1.6)points,respec-tively,which of the control group were (35.2 ±6.7)min,(9.1 ±2.5)d,(18.4 ±3.7)d and (5.3 ±1.2)points, there were significant differences between the two groups(t =5.68,4.95,6.33,1.35,all P <0.05).Third days after the operation,there were no significant differences in the pain,edema,hemorrhage scores between the two groups(all P >0.05),but seventh days after the operation,the pain,edema,hemorrhage control scores of the observation group were significantly better those of the control group(all P <0.05).The complication rate of the observation group was 5.17%,which of the control group was 17.24%,there was significant difference between the two groups(χ2 =4.25, P <0.05).Conclusion The interspincterotomy combined with PPH is an operation that meeting the requirements of modern hemorrhoid treatment.It is a safe and effective treatment.It is worthy of further promotion in the treatment of severe mixed hemorrhoid and anal fissure.
8.Therapeutic Observation of Acupoint Injection at Renying (ST9) for Cervical Vertigo
Shanghai Journal of Acupuncture and Moxibustion 2014;(10):924-925
Objective To observe the clinical efficacy of acupoint injection at Renying (ST9) in treating cervical vertigo. Method Sixty-two patients were randomized into a treatment group and a control group. The treatment group was intervened by acupoint injection at Renying, while the control group was by regular acupuncture treatment. The clinical efficacy was evaluated after a treatment course. Result The total effective rate was 93.7% in the treatment group versus 80.0% in the control group, and the difference was statistically significant (P<0.05);the symptom and function scores were significantly changed after intervention in both groups (P<0.05). Conclusion Acupoint injection at Renying is significantly effective in treating cervical vertigo.
9.Analysis of multi-resistant organisms in the hospital during the past 4 consecutive years
International Journal of Laboratory Medicine 2015;(16):2389-2391
Objective To investigate the change trend and the drug resistance rate of the multi-resistant organisms in the hospi-tal during the past four years,so as to guide the clinical medication,and strengthen the management of antibiotics application.Meth-ods Kirby-Bauer test which was recommended by the clinical and laboratory standards institute was used to conduct the suscepti-bility test,with the results evaluated based on US Clinical and Laboratory Standards Institute.Results Strains of bacteria were de-tected from January 201 1 to December 2014 in each year for the basic trend.The gram-negative bacterium was in the dominant posi-tion.The bacteria in the top five were:Escherichia coli,Staphylococcus epidermidis,Staphylococcus aureus,Pseudomonas aeruginosa and Pneumonia crayresearch coli.In each year,the overall situation of bacteria distribution had little changed.From the antimicrobial susceptibility test results,425 strains of multi-resistant bacteria were detected during the past four years.The detection rate and constituent ratio of multi-resistant bacteria then fell slightly in the first three years,but rebound in 2014.There was no statistically significant difference between the four years.Conclusion In the past four years,our hospital actively participates in monitoring and controlling the multiple drug-resistant bacteria,but nosocomial infection of the multiple drug-resistant bacteria has not been effec-tively controlled because of a variety of factors.We should continue to strengthen monitoring the clinical multiple drug-resistant bacteria,and understand the change tendency.In order to strengthen the management of the use of antibiotics and to guide clinical rational drug use,the drug sensitive test and the resistance situation of the hospital should be considered for the reasonable selection of antimicrobial agents.Strengthening the biological monitoring of clinical departments,enhancing the consciousness of sterile oper-ation of clinicians can help prevent the spread of drug-resistant strains.
10.The diagnostic value of enzyme-linked immunospot assay in AIDS patients with Mycobacterium tuberculosis infection
International Journal of Laboratory Medicine 2015;(20):3009-3010
Objective To explore the value of enzyme‐linked immunospot(ELISPOT ) assay in the diagnosis of acquired immu‐nodeficiency syndrome(AIDS) patients with Mycobacterium tuberculosis infection .Methods 42 hospitalized AIDS patients with Mycobacterium tuberculosis infection and 60 non‐tuberculosis hospitalized patients with diseases of respiratory system in the same period were recruited as observation group and control group ,respectively .ELISPOT assay ,tuberculosis antibody(TBAb) test and tuberculin skin test(TST) were performed for all the patients ,respectively .The sensitivity ,specificity and accuracy of the 3 meth‐ods were comparatively analyzed .Results The sensitivity ,specificity and accuracy of ELISPOT were 92 .9% ,93 .3% and 93 .1% . These of TBAb were 54 .8% ,71 .7% and 64 .7% ,and of TST were 47 .6% ,53 .3% and 51 .0% ,respectively .There were significant differences among three methods in sensitivity ,specificity and accuracy(P<0 .05) .The sensitivity ,specificity and accuracy of ELIS‐POT were the highest in the 3 methods(P<0 .05) .There were no significant differences between TBAb test and TST in sensitivi‐ty ,specificity and accuracy(P>0 .05) .Conclusion ELISPOT assay has relatively high diagnostic value in AIDS patients with My‐cobacterium tuberculosis infection .