OBJECTIVE: To introduce the current application of drug eluting stents in clinical practice, and investigate the advanced study of sirolimus and paclitaxel eluting stents. DATA SOURCES: An online research of Medline database was undertaken to identify the articles about drug eluting stents published between January 1996 and December 2006, with the keywords of "drug eluting stents, sirolimus eluting stents, paclitaxel-eluting stents", and language was limited to English; Meanwhile, the Chinese articles were retrieved in the Wanfang database from January 2000 to December 2006 by inputting the keywords "drug eluting stents, sirolimus eluting stents, paclitaxel eluting stents". STUDY SELECTION: Over 200 literatures were screened out, and those related with the clinical application of drug eluting stents were collected, subjecting as patients. Randomized or nonrandomized study and control or uncontrol group were all involved. Randomized control large sampling study was preferred for the similar content. Finally 30 articles were included. DATA EXTRACTION: Among 30 selected articles, 5 papers briefly introduced the characteristics of drug eluting stents, 10 papers discussed the mechanism of preventing and treating restenosis by sirolimus eluting stents and paclitaxel eluting stents, 15 papers referred to the clinical application of eluting stents. DATA SYNTHESIS: Drug eluting stent can inhibit the inflammatory reaction and cellular proliferation, delay the vascular endothelization, distinctly reduce the in-stent restenosis after percutaneous coronary intervention, and obviously develop the indication of Percutaneous intervention by releasing one or several bioactive substance to blood and surrounding tissues. Currently it is conformed in randomized control clinical trials that sirolimus eluting stents and paclitaxel eluting stents can decrease in-stent restenosis in patients with simple coronary artery stenosis, but the application on those with complex bifurcation affection and acute myocardial infarction is unknown. In addition, the high cost and in-stent thrombogenesis are also in debates. CONCLUSION: Drug eluting stents will be widely applied to reduce the in-stent restenosis and cardiovascular adverse events due to the advancement of interventional technique, modification of interventional instrument and appearance of anti-proliferation drug, which is more specific and lower poisonous and side effects.

OBJECTIVE:To evaluate the cost-effectiveness of imported and domestic cefoperazone/sulbactam sodium in treating lower respiratory infection.METHODS:60patients with lower respiratory infections were ascribed to receive im-ported or domestic cefoperazone/sulbactam sodium(2∶1)respectively,the curative effects of the drugs were monitored and evaluated by cost-effectiveness analysis.RESULTS:The costs of the two groups were3164.00yuan and828.80yuan,re-spectively(P0.05),respectively;The cost-effectiveness ratios were37.98and10.36,respectively;And the incremental cost-effectiveness ratio of the imported group vs.the domestic group was707.64.CONCLUSION:Domestic cefoperazone/sulbactam sodium is a more economical choice.

This paper deals with a preliminary experience of the selective external carotid angiography by retrocatheterism via the superficial temporal artery in 6 cases.The method and technique were completely described.The external carotid angiography in different ways was discusse.Authors believe that the external carotid angiography by retrocatherism via the superficial temporal artery is a simple and reliable method, the image being very clear and complicatins rare.The method is worth using in oral maxillofacial surgery.

In this paper,We report the treatment of ten cases of cavernous hemangioma of parotid gland in infancy.It is suggested that a surgical operation should be performed as early as pos- sible.The difficulties of the operation and the points for attention are discussed as well.

The paper reports 214 cases of the bening parotid tumors which were treated by the parotidectomy of preserving the facial nerves during 1970-1987. Superficial parotidectomy was done in 30 cases, and total parotidectomy in 184 cases. The result of the follow-up survey of 176 cases was gained. No permanent facial paralysis and recurrence occured after the parotidetomy.

This paper reports the experience of free autogenous tibial periosteum grafting for 9 pa- tients with cleft palate.No dehiscence appeared after the operation and the wound healed up well.The upper jaw occlusal film showed hyperosteogeny in two weeks after the operation. The surgical probabiity,surgical method and points for attention have been discussed.

CEA concentration in human serum, whole salive and parotid salive were determined by using radioimmunty analysis on the people who have been assayed and analysed.30 of them were normal, 9 had parotid disease but no tumor, 13 with benign parotid tumors and 16 with malignant parotid tumors.The integratve analysis were made by combining clinical features with pathological diagnoses.The results show that, in normal persons, CEA concentration in serum is

In this report,we present the measurement and observation of the main branches of ex- ternal carotid artery of 60 adults' head-neck specimens.In order to catheterize via superficial temporal artery (angiography or chemotherapy) and do arterial anastomosis,we meas- ured the angle between superficial temporal artery and external carotid artery as well as that between superficial temporal srtery and temporal bone malar process.We also measured the intimal girth of superflcial temporal artery.and calculated its internal diameter.The report is intended to offer a reference for clinical practice and Chinese constitution investigation.

Objective To evaluate the change of expression of estrogen receptor(ER) and progesterone receptor(PR) in endometrium of polycystic ovarian syndrome(PCOS) patients during induced ovulation and its clinical significance.Methods We recruited 108 PCOS patients as the disease group and 96 women with tubal infertility as the normal control group.Both groups were randomly divided into three groups with equal numbers (metaphase of generation group,metaphase of secretion group and ovulation group) and were tested the change of ER and PR levels in endometrium of PCOS patients at the fifth day after menstruation,ovulation period and the seventh day after ovulation with way of immunohistochemistry.Results There was marked change of ER and PR in the menstrual cycle of healthy controls.The levels of ER and PR were (0.89 ± 0.22) kU/L and (0.72 ±0.25) kU/L,and (1.65 ± 0.42) kU/L and (1.43 ± 0.42) kU/L respectively at metaphase of generation and (0.92 ± 0.29) kU/Land (0.87 ± 0.34) kU/L,and (1.68 ± 0.42) kU/L and (1.56 ± 0.30) kU/L respectively at metaphase of secretion.Positive gland decreased significantly during ovulation period (ER:(0.69 ± 0.35) kU/L and (0.55 ± 0.24) kU/L; PR:(0.97 ± 0.32) kU/L and (0.69 ± 0.30) kU/L).The levels of ER of stroma and positive gland in menstruation of PCOS patients were significantly higher than in menstruation of normal women during all the stages of menstrual cycle and did not have non-linear change (Metaphase of generation:(1.73 ± 0.22) kU/L and (1.89 ± 0.38) kU/L; Ovulation:(0.75 ± 0.32) kU/L and (0.63 ± 0.28) kU/L;Metaphase of secretion:(1.79 ± 0.31) kU/L and (1.90 ± 0.30) kU/L).The levels of PR in menstruation of PCOS patients were significantly lower than in menstruation of normal women during all stages of menstrual cycle (P ＜ 0.05).We did not observe trend of elevation of PR levels in PCOS patients (Metaphase of generation:(0.93 ±0.36) kU/L and (0.85 ± 0.56) kU/L; Ovulation:(0.77 ± 0.26) kU/L and (0.56 ± 0.41) kU/L) ;Metaphase of secretion:(0.98 ±0.36)kU/L and (0.88 ±0.47)kU/L).Conclusion The expressions of ER and PR in endometrium of PCOS patients are abnormal during all stages of induced ovulation.The endometrial receptivity of PCOS patients is worse than normal women.Improving the receptivity of ER and PR of PCOS patients is one of the ways to enhance pregnancy of PCOS patients.

Biliary tract cancer(BTC) is a malignart tumor which originates from biliary epithelia.Most patients with BTC present locally advanced stage or distant metastasis.Although the standard systemic chemotherapy approaches are emerging,the prognosis remains poor.Combination of gemcitabine and cisplatin can significantly prolong survival for patients,which is the standard treatment for locally advanced or metastatic BTC.Application of molecularly targeted therapies in advanced BTC is the new trend of clinical research.