The concept and characteristics of omnimedia were outlined, the effects of omnimedia on traditional in-formation service model, storage types of information resources, and personal service in medical library were analyzed, and a number of new information service models in the omnimedia era were put forward.

Bacterial disease is still the important disease hazardous to health of human being and animals.The bacterial mutation technique is an important bacterial research technique,including traditional physical and chemical and biological method,and modern genetic mutation technique.The bacterial genetic mutation technique is one of the research focus in bacteriology nowadays,the mutation strategy varies with different kinds of genetic:mutation technique.The development and application of bacterial mutation technique offers new tools for research on new bacterial vaccine,bacterial genetic function and genetic therapy etc.

An innovative educational model characterized as interesting-guiding is created in the acupuncture educational practice for foreign students. According to the innovative educational theories, teaching orders are rearranged, new teaching methods are used, and passive indoctrination is changed into creative studies and discussion, thus the educational quality is improved.

Objective: To observe the effects of needling Baihui (GV 20), Shuigou (GV 26) and Shenmen (HT 7) on cerebral glucose metabolism in patients with vascular dementia (VD) by cerebral functional imaging technique. Methods: Twenty-five patients with VD were divided into 5 groups (Group A, B, C, D and E) randomly. Patients in the Group A were treated by needling routine acupoints for hemiplegia (Acupoints of the three yang meridians of hand and foot), and besides the routine acupoints, patients in the Group B were treated by needling Baihui(GV 20), the Group C by Shuigou(GV 26), the Group D by Shenmen(HT 7), and the Group E by Baihui(GV 20), Shuigou(GV 26), and Shenmen(HT 7). All the patients were examined by Positron Emission Tomography (PET) to detect the cerebral glucose metabolism in the bilateral frontal lobes(orbital gyri), parietal lobes, temporal lobes(hippocampus and hippocampal gyrus), occipital lobes, thalamus, lentiform nucleus, caudate nuclei, cingulate gyms and cerebellum before treatments and after treatments. Results: After needling the routine acupoints for hemiplegia, glucose metabolism increased in lentiform nucleus and temporal lobe;needling Baihui(GV 20), increased in frontal lobe, temporal lobe and lentiform nucleus;needling Shuigou(GV 26), increased in frontal lobe, thalamus and lentiform nucleus; needling Shenmen(HT 7), increased in parietal lobe and lentiform nucleus; and needling these three acupoints, increased in frontal lobe, temporal lobe, thalamus and lentiform nucleus. Conclusion:Needling Baihui(GV 20), Shuigou(GV 26) and Shenmen(HT 7) affect glucose metabolism in different functional regions of the brain, and Baihui(GV 20), Shuigou(GV26) and Shenmen(HT 7) relate to different functional regions of the brain.

Hand, Foot and Mouth Disease ; diagnosis ; therapy ; Health Education ; Humans

As the efficacies of chemotherapy in the treatment of advanced non-small cell lung cancer(NSCLC) have reached a plateau, the molecularly targeted therapy becomes a new method to improve curative effects.The molecular targeted drugs include epidermal growth factor receptor inhibitors, anti-angiogenesis drugs, etc.As one of the representative drugs of EGFR inhibitors, Gefitinib, has a low clinical benefit index.Erlotinib, the first EGFRTK inhibitor, can enhance the survival of patients, and may serve as a potential choice for the first-line treatment of advanced NSCLC.Bevacizumab combined with chemotherapy has shown a favorable clinical effect in the first-line treatment, and it is also the first anti-angiogenesis drug approved by the FDA that can be used in cancer treatment.These drugs, together with clinical and experimental progress in many other targeted drugs, have shown a favorable prospect for targeted drugs in the treatment of advanced non-small cell lung cancer.

Objective To investigate the ideal methods for correction of lower eyelid retraction by lateral canthal anchoring.Methods The authors retrospectively reviewed the records of 126 patients(207 eyelids) operated on between June 1999 and 2005 by one senior surgeon.The age of the patients ranged from 28 to 72 years(mean,46 years).Transcanrhal canthopexy was used in 20 patients(33 eyes);The 3 mm tarsal strip procedure was used in 35 patients(57 eyes);Transcanrhal canthopexy combined with Hamra's lower blepharoplasty was used in 26 patients(45 eyes).The tarsal strip procedure combined with Hamra's procedure was used in 45 patients(72 eyes).75 patients(123 eyes) were followed up for 6～12 months.Mean follow-up time was 8 months. Results Of them,125 patients were uniformly satisfied with their cosmetic and functional outcome at last follow-up;one patient had undercorrection of retraction.There were no major complications and only one minor complications(corneal irritation from graft sutures),which resolved in the early follow-up period.Conclusions The lateral canthal anchoring is an effective,aesthetic,and functional treatment for moderate to severe lower eyelid retraction resulting from multiple causes.This procedure is associated with predictable results,a low morbidity rate,and high patient satisfaction.

Objective To carry out the performance evaluation to insure security of inner canister during the design phase, which is the important thin component of the portable sterilizater. Methods The software Mechanica, one of the module of Pro/Engineer was implemented to the flexure analysis of the inner canister. Results The stabilization and strength of inner canister satisfied requirements of the design. Conclusion Not only the security of design data can be proved but the cost and cycle of design can be reduced by using the method of expansion simulation analysis at the same time of the design phase of the equipment.

BACKGROUND:Nano-hydroxyapatite/polyamide 66 is a new nanobionic composite material and has good biocompatibility and bone conduction, but after implantation, whether the composite material can bind to vertebral bone interface and whether it is safe in clinical use stil need further studies. OBJECTIVE: To observe the ability of nano-hydroxyapatite/polyamide composite binding to the interface of artificial humeral head. METHODS: The rabbits were randomly divided into two groups: composite group was implanted with nano-hydroxyapatite/polyamide composites; control group implanted with autologous bone. After the replacement, rabbit bone marrow mesenchymal stem cels were subjected to primary culture, and then the cels were co-cultured with the composite material. RESULTS AND CONCLUSION:At 24 hours after culture, bone marrow mesenchymal stem cels grew wel on the composite materials. The cel adhesion rate was significantly higher in the composite group than the control group at 1 and 4 hours after culture (P < 0.05). After co-culture 4.5, 5.5, 6.5 hours, the absorbance value of cels in the composite group was higher than that in the control group (P < 0.05). At 24 weeks after replacement, changing ranges in the proportions of bone tissue and fibrous layers on the implant surface as wel as coverage rate in the composite group were the highest (P < 0.05). These findings indicate that the nano-hydroxyapatite/ polyamide composite implant has a certain binding capacity, which can make a good interface osseointegration.

Objective To compare the early efficacy of two different ways of rehabilitation exercises in total knee arthroplasty (TKA) patients. Method From January 2011 to January 2014,136 patients having undergone TKA were randomly divided into two groups. In group A , patients exercised under the guidance with doctor. In group B, patients exercised by using continuous passive movement (CPM) machine. Compared the data from the two groups including range of motion (ROM) of the knee joint, knee function score (KFS) and circumference of the knee joint, t test of independent sample was utilized in the research. Results All patientswere followed up in 4 weeks. The ROM and KFS of Group A was significantly better than Group B (P < 0.05). The knee circumference had no statistically significant difference between two groups (P> 0.05).Conclusion Group A and B are effective methods in TKA patients in early rehabilitation training. But training under the guidance of doctor has greater advantages than CPM.