1.The EEG analysis with the symptoms headed by "abdominal pain,fever" of viral encephalitis in children
Chinese Journal of Primary Medicine and Pharmacy 2010;17(1):19-20
Objective To discuss the value of EEG in early diagnosis and prognosis appraisal of children with the symptoms headed by"abdominal pain ferer"take the"abdominal pain,fever"as the first symptoms of viral encephalitis.Methods 150 cases of"abdominal pain,fever"as the first symptom diagnosed of viral encephalitis children were chosen for the EEG analysis before and after treatment.Results EEG abnormalities 117 cases,33 cases of normal.The EEG abnormality rate of abnormality is 78% ,showed diffuse or localized slow-wave number.There are two groups of children with temporal epileptiform discharges occur.There are 107 cases of abnormal EEG returned to normal and another 10 cases significantly improved in the 117 cases after symptomatic treatment of 1~2 weeks.Conclusion The EEG inspection is help with"abdominal pain,fever" as the first symptoms of viral encephalitis in children with early diagnosis,symptomatic treatment and prognosis.
2.Localized occipital region abnormity of infantile EEG and its influence factors
Chinese Journal of Primary Medicine and Pharmacy 2009;16(5):835-836
Objective To explore pediatric EEG in localized region abnormity and influence factors. Methods 51 children with EEG abnormity were retrospectively analyzed. Results In this group,there are 45 children with EEG abnormity in normal situation,and 6 of 51 childrened appear abnormity in induced tests. All the 51 childrened appeal abnormai brain wave in occipital region in varying degree. Conclusion Pediatric occipital region localization abnormal EEG may be hints related to children paroxysmal disorder, Miscellaneous factors can influence children paroxysmal disorder include all kinds of etiology, pathologic physiology signs and symptoms, age and individual variation ect.
3.Clinical Study on the Influence of Bushen Hxuoxue Zhuyun Decoction on Endometrial Growth and Follicle
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(10):-
Objective To observe the clinical therapeutic effect of Bushen Huoxue Zhuyun Decoction and its influence on the endometrial growth and the follicle, and supply scientific evidence for the clinical use of Bushen Huoxue Zhuyun Decoction. Methods 90 cases of patients with anovulatory sterility of kidney deficiency syndrome were divided into two groups randomly. Treatment group (50 cases) and control group (40 cases) were given Bushen Huoxue Zhuyun Decoction and clomiphene citrate respectively. Results In the treatment group, the cured rate was 24%, markedly effective rate was 56%, effective rate was 16%, and the total effective rate was 96%. In the control group, the cured rate was 15%, markedly effective rate was 17.5%, effective rate was 25%, and the total effective rate was 82.5%. There was significant difference between the two groups by statistical analysis (P 0.05). The thickness of uterine endometrium of pre-treatment and post-treatment in treatment group was significant by statistical analysis (P
4.Condition of voice of teachers in one college.
Chinese Journal of Industrial Hygiene and Occupational Diseases 2009;27(6):353-354
Adult
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Faculty
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Female
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Humans
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Male
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Middle Aged
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Voice
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Voice Disorders
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epidemiology
5.Inflammatory factor alteration and intervention for atherosclerosis after stenting
Chinese Journal of Tissue Engineering Research 2009;13(39):7711-7715
Atherosclerosis is a multifactorial disease and mediated by chronic inflammation from initiation to progression. Inflammatory factors of this process, such as C-reactive protein, interleukin-6, cell adhesion molecules and tumor necrosis factor-a, not only involve in atherosclerosis-related disease process, but also indicate the risk of cardiovascular events. Inflammatory factors level plays a significant role in diagnosis, treatment and prognosis of atherosclerosis-related disease, such as acute coronary syndrome. Recent studies have shown that there is a marked inflammatory response after stenting, which plays an important role in the vascular remodeling process, especially in-stent restenosis. Therefore, it is necessary to explore the molecular mechanism and pathological changes in the process of inflammation and to study prevention and treatment of the inflammation. We believe that inflammatory processes will be new targets of therapy in preventing or treating atherosclerosis and its complications.
6.Effect of hyperoxia on the airway and vascular development in fetal lung and the intervention of dexamethasone
Chinese Pediatric Emergency Medicine 2008;15(4):342-344
Objective To investigate the effects of dexamethasone on the airway development and vasculogenesis in cultured human fetal lung exposed to hyperoxia.Methods Human fetal lung at the pseudoglandular stage of development were cultured either in normoxia(21%O2,5%CO2)or hyperoxia(95%O2,5% CO2)for 72 hours.Dexamethasone was added into the culture medium at the concentration of 10-6 mol/L.Whereas ethanol at the same concentration was as control.Harvested tissue wss stained for pancytokeratin to I dentify epithelial cells.CD31 aS a specific antibody of endothelial cell.The effects of lung morphometry were analyzed using computer-assisted image analysis software to ealeuhte the thickness of airways,surface area occupied by airways and the distance of vessels to the nearest airway as well as the surface area of blood vessels.Results The lung architecture remained largely unchanged in normoxia for 72 hours culture,whereas hyperoxic culture of lungs resulted in significant dilation of airways and thinning of epithelium.The surface area occopied by airways increased significantly(P<0.05).The blood vessels in interstium were more close to the airway epithelium in the hyperoxic lung(50 μm)as compared with normoxia group.Meanwhile,the proportion of the blood wessels in interstium of hyperoxia group(4.0%)Was higher than those of normoxia group (4.2%)and hyperoxia with dexamethasone(5.4%)(P<0.05).Dexamethasone has the protective effect on lungs exposed tO hyperoxia.Conclusion Our resulta showed that hyperoxia resulted in the simple airways and the decreased bkxxl vessel density in interstitium of cultared human fetal lung.Dexamethasone has protective effect on fetal lungs exposed to hyperoxia and can promote lung mature.
7.Clinical effect of acute cerebral infarction treated by ginkgo damo injection and it's influence on SOD, MDA and NO.
Chinese Journal of Integrated Traditional and Western Medicine 2004;24(6):559-560
Aged
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Cerebral Infarction
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drug therapy
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Drug Therapy, Combination
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Drugs, Chinese Herbal
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therapeutic use
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Female
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Free Radical Scavengers
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therapeutic use
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Ginkgo biloba
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Humans
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Male
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Malondialdehyde
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blood
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Middle Aged
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Nitric Oxide
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blood
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Phytotherapy
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Superoxide Dismutase
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blood
8.Significance of thyroid stimulating antibody and thyroid stimulating-blocking antibody in children with autoimmune thyroid disease
Chinese Journal of Applied Clinical Pediatrics 2016;31(8):600-603
Objective To study the significance of thyroid stimulating antibody (TSAb) and thyroid stimulating-blocking antibody (TSBAb) in children with Graves' disease (GD) or Hashimoto's thyroiditis (HT).Methods Five hundred and twenty-seven cases of serum from 180 children with autoimmune thyroid disease (AITD) children were divided into 282 cases of GD and 245 cases of HT.According to the status of thyroid function,they were divided into 157 cases of hyperthyroidism,91 cases of hypothyroidism and 279 cases of normal thyroid.GD group was subdivided into 127 GD hyperthyroidism and 155 GD remission;HT group was subdivided 30 HT hyperthyroidism,124 HT remission and 91 HT hypothyroidism.Seventy-nine healthy children were taken as the healthy control group.Free triiodothyronine(FT3),free thyroxine(FT4) and sensitive thyroid stimulating hormone(TSH) were detected by chemoluminescence.Serum TSAb and TSBAb were detected by serum TSAb or TSBAb enzyme linked immunosorbent assay (ELISA),respectively.The differences in TSAb and TSBAb among each group were compared and analyzed of find out the relationship between TSAb and TSBAb was performed.Beside,the correlation between TSAb and TSBAb with FT3,FT4,and TSH were analyzed.Results (1) TSAb levels were significant (F =11.995,all P =0.000):the GD group (0.727 ± 0.157) > HT group (0.605 ± 0.148) > healthy control group (0.350 ± 0.105);the difference was significant(F =109.165,P =0.000) among hyperthyroidism group (0.745 ± 0.169) > normal thyroid group (0.647 ± 0.153) >hypothyroidism group(0.612 ±0.144) >healthy control group (0.350 ±0.105);the difference was significant(F=156.712,P =0.000) in the GD hyperthyroidism group(0.747 ±0.17) > GD remission group (0.640 ± 0.16) > healthy control group (0.350 ± 0.105);the difference was significant (F =109.165,P =0.000) in the HT hyperthyroidism group(0.739 ±0.140) >HT remission group(0.655 ±0.135) > HT hypothyroidism group(0.612 ± 0.140) >healthy control group (0.350 ±0.105).(2) TSBAb levels were significantly different(F =15.610,P =0.000):the HT group(0.704 ±0.633) > GD group(0.567 ±0.178) > healthy control group (0.334 ±0.104);the difference was significant(F =13.311,P =0.000) in the hypothyroidism group (0.693 ± 0.125) > remission group (0.648 ±0.446) >hyperthyroidism group(0.562 ±0.181) >healthy control group(0.334 ±0.104);the difference was significant(F =19.269,P =0.000) in the GD remission group (0.672 ±0.572) > GD hyperthyroidism group (0.550 ± 0.187) > healthy control group (0.334 ± 0.104);HT hypothyroidism group (0.693 ± 0.725) was higher than HT hyperthyroidism group(0.618 ±0.142) and HT remission group (0.619 ±0.199),the difference was not significant between HT hyperthyroidism group and HT remission group(F =12.208,P =0.000).(3) TSAb level was positively correlated with TSBAb,FT3 and FT4(r =0.162,0.091,0.194,all P < 0.05) and was negatively correlated with TSH (r =-0.224,P < 0.05).TSBAb levels were negatively correlated with FT3 (r =-0.155,P < 0.05) and was positively correlated with TSH (r =0.131,P < 0.05).Conclusions Thyroid function was related to the serum levels of TSAb and TSBAb.TSAb and TSBAb could be regarded as an important predictive index for children with AITD during the treatment period.
9.Proper response to mother-to-child transmission of hepatitis B virus
Journal of Clinical Hepatology 2014;30(11):1221-1224
Hepatitis B virus (HBV)infection and its chronicity is a serious public health problem,and mother -to -child transmission (MTCT)of HBV is one of the most common routes of infection.The risk factors for the MTCT of HBV and corresponding measures are reviewed from the aspects of assessment/screening before pregnancy,intervention during pregnancy,combined immunization for newborns,etc.,and it is pointed out that the physicians in the departments of gynecology&obstetrics and liver diseases play a key role in resolving this issue.
10.Practice of Clinical Pharmacists Participating in Drug Therapy for Pregnant Patients with Asthma
China Pharmacy 2015;(23):3292-3293
OBJECTIVE:To explore the significance of clinical pharmacists providing pharmaceutical care for pregnant patients with asthma in respiratory department. METHODS:Clinical pharmacists participated in the analysis of 2 cases of pregnancy complicating with asthma and applied pharmaceutical suggestion and therapy plan as penicillin anti-infective thera-py,intravenous dripping of magnesium sulfate combined with doxofylline,albuterol aerosol treatment instead. RESULTS:The asthma symptom had been relieved significantly and then the patients were discharged from the hospital after clinical phar-macists disposed the symptom appropriately. CONCLUSIONS:The participation of clinical pharmacists in pharmaceutical care for pregnant patients with asthma in respiratory department. Can improve the prognosis effectively and guarantee the safety of drug use.