1.Studies on the Antivacterial Effect of Cephalosporin Derivatives.
Korean Journal of Dermatology 1979;17(6):397-403
The minimal inhibitory concentration(MIC) of cephalosporin derivatives, (cephaloridine, cefazolin sodium, cephradine, cephapirin aodium, cephacetrile sodium, and cephalexin from various Korean drug companies) for Staphykcoccus aureus ATCC 25923 and Escherichia coli ATCC 25922 was measured by the tube dilution method, using Mueller-Hinton broth. The results obtained were as follows: 1) The MIC of each individual cephalosporin derivative, although produced by different manufacturers, was similiar or equal. 2) Against Staphyloeoccus aureus, cephaloridine and cephapirin had the lowest MIC while cephradine and, cephalexin the highest. Against E. coli, cephaloridine and cefazolin had the lowest MIC while cephradine and cephalexin the highest. 3) The MIC against Staphylococcus aureus was l5.6 to 250 times lower than that against E. coli in all cephalosporin derivatives. 4) The MIC against Staphylococcus aureus ranges from 0.0125 to l.0ug/ml and against E. coli from 1. 56 to 25ug/ml in all cephalasporin derivatives.
Cefazolin
;
Cephacetrile
;
Cephalexin
;
Cephaloridine
;
Cephapirin
;
Cephradine
;
Escherichia coli
;
Staphylococcus aureus
2.T1 bladder tumor: a heterogeneous and potentially dangerous group.
Journal of the Korean Cancer Association 1991;23(4):843-852
No abstract available.
Urinary Bladder Neoplasms*
;
Urinary Bladder*
3.Chronic psychosis in Turner's syndrome.
Hyeon Jeong LEE ; Jeong Gee KIM
Journal of Korean Neuropsychiatric Association 1993;32(2):266-272
No abstract available.
Psychotic Disorders*
;
Turner Syndrome*
4.The Effect of Metformin Therapy on Clomiphene Citrate-resistant Polycystic Ovarian Syndrome Women.
Korean Journal of Fertility and Sterility 2001;28(4):255-264
OBJETIVE: This study was performed to investigate the effect of metformin therapy on ovulation induction & pregnancy rate in clomiphene citrate-resistant PCOS women. METHOD: This study used a randomized, single-blinded, case-controlled methods. Total study group consisted of 21 women who showed clomiphene citrate-resistant parttern on previous ovulation induction cycles. Patients of metformin group received metformin 500 mg three times daily, for 7 weeks. Control group received none. Metformin group was consisted of 10 women and control group was consisted of 11 women. Then clomiphene was administrated at daily 50 mg for 5 days to both groups. Clomiphene dosage was increased to daily 150 mg until ovulation was occurred. Before and After metformin treatment, blood samples for measurement of insulin, glucose, steroids were obtained. RESULTS: In the metformin and control groups, 6 of 10 women (60%) and 2 of 11 women (18%) ovulated. And 4 of 10 women (40%) and 0 of 11 women (0%) conceived. Comparisons between the groups were significant. CONCLUSION: In PCOS women who are resistant to CC, metformin use increased the ovulation rate and pregnancy rate from CC treatment, significantly.
Case-Control Studies
;
Clomiphene*
;
Female
;
Glucose
;
Humans
;
Insulin
;
Insulin Resistance
;
Metformin*
;
Ovulation
;
Ovulation Induction
;
Polycystic Ovary Syndrome*
;
Pregnancy Rate
;
Steroids
5.Screening of urinary tract infection in high-risk neonates.
Hyeon Joo CHOI ; Seung Joo LEE
Journal of the Korean Pediatric Society 1992;35(12):1683-1689
No abstract available.
Humans
;
Infant, Newborn*
;
Mass Screening*
;
Urinary Tract Infections*
;
Urinary Tract*
6.Obstructive Sleep Apnea and Type 2 Diabetes.
Hyeon Hui KANG ; Sang Haak LEE
Sleep Medicine and Psychophysiology 2009;16(2):61-64
Obstructive sleep apnea (OSA) has been definitively shown to be a risk factor for the development of cardiovascular disease and mortality. Recent reports have indicated that obstructive sleep apnea is associated with insulin resistance and impaired glucose metabolism, also have type 2 diabetes. The potential mechanisms leading to the development of type 2 diabetes in OSA patients are likely to be various. Reduced physical activity resulting from daytime somnolence, sympathetic nervous system activation, intermittent hypoxia, sleep fragmentation and sleep loss, dysregulation of the hypothalamic-pituitary axis, alteration in adipokine profiles, and activation of inflammatory pathways have been proposed. Based on the current evidence, clinicians should assess the risk of OSA in patients with type 2 diabetes and, conversely, consider that possibility of glucose intolerance in patients with OSA. Further large-scale and long-term follow-up studies in patient populations with selected by reliable but inexpensive diagnostic measures, controlled for potential confounder factor, are needed.
Adipokines
;
Anoxia
;
Axis, Cervical Vertebra
;
Cardiovascular Diseases
;
Glucose
;
Glucose Intolerance
;
Humans
;
Insulin Resistance
;
Motor Activity
;
Risk Factors
;
Sleep Apnea, Obstructive
;
Sleep Deprivation
;
Sympathetic Nervous System
7.A case of choleasteatoma of the frontal sinus.
Sang Hyeon KIM ; Sang Cheol LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(1):178-183
No abstract available.
Frontal Sinus*
8.Taxonomic Studies on the Genus Marssonina in Korea.
Hyun Tae LEE ; Hyeon Dong SHIN
Mycobiology 2000;28(1):39-46
Eight species of Marssonina parasitic on 21 species of host plants from Korea are described and illustrated. They are Marssonina brunnea (Ellis & Everh.) Magnus, M. capsulicola (Rostr.) Magnus, M. celastri H.D. Shin & H.T. Lee, M. coronaria (Ellis & Davis) Davis, M. fragariae (Lib.) Kleb., M. juglandis (Lib.) Magnus, M. rosae (Lib.) Died. and M. sennenis (Gonz. Frag.) Vassiljevsky & Karak. Of these, M. capsulicola and M. coronaria sometimes poss three-celled conidia and M. sennenis is characterized by a short appendage at the basal end of the conidia. Morphological features of conidia and host ranges were of taxonomic values for species delimitation.
Fragaria
;
Host Specificity
;
Korea*
;
Rosa
;
Spores, Fungal
9.Effectiveness of Bradycardia as a Single Parameter in the Pediatric Acute Response System.
Yu Hyeon CHOI ; Hyeon Seung LEE ; Bong Jin LEE ; Dong In SUH ; June Dong PARK
Korean Journal of Critical Care Medicine 2014;29(4):297-303
BACKGROUND: Various tools for the acute response system (ARS) predict and prevent acute deterioration in pediatric patients. However, detailed criteria have not been clarified. Thus we evaluated the effectiveness of bradycardia as a single parameter in pediatric ARS. METHODS: This retrospective study included patients who had visited a tertiary care children's hospital from January 2012 to June 2013, in whom ARS was activated because of bradycardia. Patient's medical records were reviewed for clinical characteristics, cardiologic evaluations, and reversible causes that affect heart rate. RESULTS: Of 271 cases, 261 (96%) had ARS activation by bradycardia alone with favorable outcomes. Evaluations and interventions were performed in 165 (64.5%) and 13 cases (6.6%) respectively. All patients in whom ARS was activated owing to bradycardia and another criteria underwent evaluation, unlike those with bradycardia alone (100.0% vs. 63.2%, p = 0.016). Electrocardiograms were evaluated in 233 (86%) cases: arrhythmias were due to borderline QT prolongation and atrioventricular block (1st and 2nd-degree) in 25 cases (9.2%). Bradycardia-related causes were reversible in 202 patients (74.5%). Specific causes were different in departments at admission. Patients admitted to the hemato-oncology department required ARS activation during the night (69.3%, p = 0.03), those to the endocrinology department required ARS activation because of medication (72.4%, p < 0.001), and those to the gastroenterology department had low body mass indexes (32%, p = 0.01). CONCLUSIONS: Using bradycardia alone in pediatric ARS is not useful, because of its low specificity and poor predictive ability for deterioration. However, bradycardia can be applied to ARS concurrently with other parameters.
Arrhythmias, Cardiac
;
Atrioventricular Block
;
Body Mass Index
;
Bradycardia*
;
Electrocardiography
;
Endocrinology
;
Gastroenterology
;
Heart Arrest
;
Heart Rate
;
Hospital Rapid Response Team
;
Humans
;
Medical Records
;
Pediatrics
;
Retrospective Studies
;
Sensitivity and Specificity
;
Tertiary Healthcare
10.An experimental study of the effect of alumina and zirconia on mechanical properties of dental core porcelain.
Hyeon Soo SHIN ; Sang Jin LEE ; Keun Woo LEE
The Journal of Korean Academy of Prosthodontics 1993;31(3):317-349
No abstract available.
Aluminum Oxide*
;
Dental Porcelain*