1.Effects of Alginate Culture on Viability, Proliferation, and Phenotype of Canine Articular Chondrocytes.
Hyeong Geun PARK ; Jeong Im WOO ; So Ra PARK ; Han Jo LIM ; Byoung Hyun MIN
Journal of Korean Orthopaedic Research Society 2001;4(1):24-31
No Abstract Available.
Chondrocytes*
;
Phenotype*
2.Evaluation of Skeletal and Dental Maturity in Relation to Vertical Facial Types and the Sex of Growing Children
Seon-Gyeong JO ; Byounghwa KIM ; Jewoo LEE ; Jiyoung RA
Journal of Korean Academy of Pediatric Dentistry 2021;48(4):414-424
The purpose of this retrospective study was to evaluate the skeletal and dental maturity according to the vertical facial type and sex in Korean children in the developmental stage.
In total, 184 participants aged 8 - 14 years were selected and divided into three groups based on the mandibular plane angle. For the comparison between the sexes, the three groups were each divided into male and female subgroups. The skeletal and dental maturity were assessed using lateral cephalograms, hand-wrist radiographs and panoramic radiographs.
The vertical growth group showed significantly greater cervical vertebral and hand-wrist maturity than that in the horizontal growth group. Dental maturity was the highest in the vertical growth group. Girls showed greater skeletal maturity than boys, and no distinct difference was observed between the dental maturity of the sexes.
Analysis of the vertical facial type in children can provide ancillary indicators that may help determine the optimal timing for orthodontic treatment initiation. Earlier initiation of orthodontic treatment may be considered for patients with vertical facial growth patterns.
3.A Study on Position of the Mental Foramen in Children Using Panorama
Eunjeong JO ; Jewoo LEE ; Jiyoung RA
Journal of Korean Academy of Pediatric Dentistry 2019;46(2):183-189
The purpose of this study was to investigate the changes of the position of the mental foramen according to age by using panorama of children with mixed and early permanent dentition. 180 panorama of 6 to 13-year-old boys and girls were analyzed and PiView(Infinitt, Korea) program was used.The horizontal position of the mental foramen was evaluated by the relative position of the teeth. The vertical position of the mental foramen was evaluated by the ratios between the distance from the center of the mental foramen to the inferior border of the mandible and the distance from to the alveolar crest to the inferior border of the mandible.The mental foramen was horizontally located in the anterior aspect of the second primary molar(premolar), and vertically slight below the half of mandibular body. As the age increased, it moved to the posterior and the downward and showed a significant correlation with age.
Adolescent
;
Child
;
Dentition, Permanent
;
Female
;
Humans
;
Mandible
;
Tooth
4.A Comparative Study of the Importance and Satisfaction of Emergency Room Patient-nurse Communication Needs
Health Communication 2019;14(1):1-9
BACKGROUND: The purpose of this study was to identify and compare perception of importance and satisfaction regarding communication needs among patients and nurses in emergency centers.METHODS: This study used a cross sectional design and included 64 of patients and 37 of nurses in emergency centers of university hospitals located in Daejeon. Data were collected with a self-administered questionnaire between April 2017 and June in 2017. Data analysis was conducted using descriptive statistics.RESULTS: Regarding importance of communication needs, both groups of the patients and the nurses significantly recognized the importance of providing information such as performed tests and treatments and visiting time of charged physicians. Meanwhile, emotional supports and concern about social or cultural needs was recognized as less important communication needs among the patients and nurses. Regarding satisfaction of communication needs, patients were less satisfied with the needs they regarded as the most important and nurses showed moderate levels of satisfaction. This indicates that patients and nurses differ in the standards and expectations for communication performance.CONCLUSION: It is important that emergency room nurses should recognize the current situation in which the patients' desired communication needs are not being met and they should start to focus improvement effort and new directions of emergency room care systems to meet the communication needs.
Emergencies
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Emergency Service, Hospital
;
Hospitals, University
;
Humans
;
Statistics as Topic
5.Influence of gestational age at exposure on the prenatal effects of gamma-radiation.
Sung Ho KIM ; Se Ra KIM ; Yun Sil LEE ; Tae Hwan KIM ; Sung Kee JO ; Cha Soo LEE
Journal of Veterinary Science 2001;2(1):37-42
The objective of this investigation was to evaluate the influence of gestational age at exposure on the prenatal effects of gamma-radiation. Pregnant ICR mice were exposed to a single dose of 2.0 Gy gamma-radiation at a gestational 2.5 to 15.5 days post-coitus (p.c.). The animals were sacrificed on day 18 of gestation and the fetuses were examined for mortality, growth retardation, change in head size and any other morphological abnormalities. The only demonstrable effect of irradiation during the preimplantation period was an increase in prenatal mortality. Resorptions were maximal on post-exposure day 2.5 after conception. The pre-implantation irradiated embryos which survived did not show any major fetal abnormalities. Small head, growth retardation, cleft palate, dilatation of the cerebral ventricle, dilatation of the renal pelvis and abnormalities of the extremities and tail were prominent after exposure during the organogenesis period, especially on day 11.5 of gestation. Our results indicate that the late period of organogenesis in the mouse is a particularly sensitive phase in terms of the development of the brain, skull and extremities.
Abnormalities, Radiation-Induced/*pathology
;
Animals
;
Bone and Bones/abnormalities/radiation effects
;
Female
;
Fetal Death
;
*Gamma Rays
;
*Gestational Age
;
Mice
;
Mice, Inbred ICR
;
Pregnancy
;
Pregnancy, Animal/*radiation effects
;
Prenatal Exposure Delayed Effects
6.Effects of TGF- beta 3 pretreatment in vitro on the differentiation of rabbit mesenchymal stem cell in vivo.
Hyeong Geun PARK ; So Ra PARK ; Han Jo LIM ; Byoung Hyun MIN
Journal of Korean Orthopaedic Research Society 2001;4(2):167-176
PURPOSE: Bone and cartilage were manufactured by using tissue engineering of mesenchymal stem cell (MSC) which can differentiate into variety of cell types. MATERIAL AND METHOD: MSC was isolated and cultured from the rabbit weighing 500g, and it was seeded into PGA mesh and pre-cultured for 1 week with different TGF- beta 3 treated conditions. It was implanted into nude mice and tissues generated were recovered from 1, 2, 3, 4, 8 ,and 12 weeks respectively. Degree of bone and cartilage formation was analyzed with histology and immunohistochemistry assay. RESULT: Pre-culture condition with TGF- beta 3 treatment showed early start of chondrogenic differentiation, and degree of bone and cartilage formation was promoted as time passed. But both of the cases differentiated into complete bone after 12 weeks. CONCLUSION: The results show that pretreatment of TGF- beta 3 promotes the differentiation process in vivo condition under the in vivo system where MSC differentiate into bone via cartilage formation.
Animals
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Cartilage
;
Immunohistochemistry
;
Mesenchymal Stromal Cells*
;
Mice
;
Mice, Nude
;
Tissue Engineering
7.Serum Low-Density Lipoprotein Cholesterol Levels and Depressive Mood in Korean Adults: A Nationwide Population-Based Study
Seog-Young JO ; Yu-Jin KWON ; A-Ra CHO
Korean Journal of Family Medicine 2022;43(1):63-68
Background:
The association between serum cholesterol levels and depression has been studied extensively; however, results are inconsistent. This study aimed to investigate the association between low-density lipoprotein cholesterol (LDL-C) levels and depressive symptoms among Korean adults.
Methods:
This cross-sectional study used data obtained from the 2007–2015 Korea National Health and Nutrition Examination Survey. In total, 40,904 adults were included in the final analysis. Participants were categorized into five groups according to their LDL-C levels, using the Korean guidelines for dyslipidemia. Symptoms of depression were evaluated using a self-reported questionnaire. Weighted logistic regression was used to examine the relationship between LDL-C levels and self-reported depressive symptoms.
Results:
Compared with the intermediate category, the lowest (<70 mg/dL) and highest (≥160 mg/dL) LDL-C categories were associated with depressive symptoms, after adjusting for potential confounding factors (odds ratio [OR], 1.191; 95% confidence interval [CI], 1.008–1.409; OR, 1.241; 95% CI, 1.073–1.435, respectively). The highest LDL-C category was positively associated with depressive symptoms in those who were middle-aged, female, had a low body mass index, and taking or not taking dyslipidemia medications.
Conclusion
A U-shaped association was identified between LDL-C categories and self-reported depressive symptoms. Our findings suggest that LDL-C levels that are too low or too high are associated with self-reported depressive symptoms. Further prospective studies are needed to determine the causal relationship of this association.
8.Diagnosis of Functional Dyspepsia: a Systematic Review.
Hye kyung JUNG ; Bo Ra KEUM ; Yoon Ju JO ; Sam Ryong JEE ; Poong Lyul RHEE ; Young Woo KANG
The Korean Journal of Gastroenterology 2010;55(5):296-307
This review tried to set up an initial diagnostic strategy in patients with functional dyspepsia. Dyspepsia was defined as chronic or recurrent pain, or discomfort centered in the upper abdomen (i.e., epigastrium), excluding heartburn and acute abdominal conditions. We reviewed the available data in order to produce currently applicable recommendations for the diagnosis of dyspepsia in Korea. Two investigators independently conducted an independent literature search of published reports on dyspepsia and diagnosis, including alarm symptoms, Helicobacter pylori (H. pylori) test, empirical pharmacological therapy, and early upper gastrointestinal (GI) endoscopy. The evidence concerning alarm features does not allow clear guideline whether early endoscopy should be performed or not. In Asia, including Korea, the prevalence of H. pylori and gastric cancer are high. Therefore, 'H. pylori test and treatment' strategy is not suitable for the initial diagnostic approach for uninvestigated dyspepsia. Long-term empirical pharmacological therapy is not recommended in Korea because of the possibility of missing or delaying the diagnosis of gastric cancer. There have been a lot of evidences showing that early upper GI endoscopy might be more effective than empirical medication, which is different from Western countries. However, cut-off age for early endoscopy is not clear, especially in case of young age. Further research is necessary to define highrisk age for gastric cancer and for a health economic study in the management of patients with dyspepsia in Korea.
Dyspepsia/*diagnosis
;
Endoscopy, Digestive System
;
Helicobacter Infections/diagnosis
;
Helicobacter pylori
;
Humans
9.Diagnosis of Functional Dyspepsia: a Systematic Review.
Hye kyung JUNG ; Bo Ra KEUM ; Yoon Ju JO ; Sam Ryong JEE ; Poong Lyul RHEE ; Young Woo KANG
The Korean Journal of Gastroenterology 2010;55(5):296-307
This review tried to set up an initial diagnostic strategy in patients with functional dyspepsia. Dyspepsia was defined as chronic or recurrent pain, or discomfort centered in the upper abdomen (i.e., epigastrium), excluding heartburn and acute abdominal conditions. We reviewed the available data in order to produce currently applicable recommendations for the diagnosis of dyspepsia in Korea. Two investigators independently conducted an independent literature search of published reports on dyspepsia and diagnosis, including alarm symptoms, Helicobacter pylori (H. pylori) test, empirical pharmacological therapy, and early upper gastrointestinal (GI) endoscopy. The evidence concerning alarm features does not allow clear guideline whether early endoscopy should be performed or not. In Asia, including Korea, the prevalence of H. pylori and gastric cancer are high. Therefore, 'H. pylori test and treatment' strategy is not suitable for the initial diagnostic approach for uninvestigated dyspepsia. Long-term empirical pharmacological therapy is not recommended in Korea because of the possibility of missing or delaying the diagnosis of gastric cancer. There have been a lot of evidences showing that early upper GI endoscopy might be more effective than empirical medication, which is different from Western countries. However, cut-off age for early endoscopy is not clear, especially in case of young age. Further research is necessary to define highrisk age for gastric cancer and for a health economic study in the management of patients with dyspepsia in Korea.
Dyspepsia/*diagnosis
;
Endoscopy, Digestive System
;
Helicobacter Infections/diagnosis
;
Helicobacter pylori
;
Humans
10.Laparoscopic management of uterine anomaly associated with agenesis of unilateral kidney and pelvic endometriosis: two case reports.
Jo Eun KIM ; Hyun Ju PARK ; Seung A LEE ; Shan Ni LIU ; Ae Ra KANG ; Eun Hee LEE
Korean Journal of Obstetrics and Gynecology 2006;49(4):950-955
Unicornuate uterus with a rudimentary horn hematometra and bicornuate uterus with unilateral hematometra is rare congenital anatomic anomalys of the female genital system. these patients present with dysmenorrhea, dyspareunia, pelvic mass, urinary tract anomalies and pelvic endometriosis. We have experienced a case of rudimentary uterine horn hematometra with agenesis of ipsilateral kidney and pelvic endometriosis in a 18 years old girl and a case of bicornuate uterus with unilateral hematometra associated with agenesis of ipsilateral kidney and pelvic endometriosis in a 14 years old girl. and we treated by laparoscopic management. So we report two cases with a brief review of literatures.
Adolescent
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Animals
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Dysmenorrhea
;
Dyspareunia
;
Endometriosis*
;
Female
;
Hematometra
;
Horns
;
Humans
;
Kidney*
;
Urinary Tract
;
Uterus