1.Application of medical signal processing based on theory and method of chaos
International Journal of Biomedical Engineering 2006;0(02):-
Reviewing the theory of chaos in the field of nonlinear dynamics, this paper summarized theory of chaos and its applications in medical signal processing including electroencephalogram(EEG) signal?electrocardiogram(ECG) signal?electromyogram(EMG) signal, etc. The foreground is reviewed to advance the study and application of nonlinear dynamics theory in biomedical engineering.
2.Characteristics of medical and health literature novelty assessment in institutions of armed forces, its problems and solutions
Chinese Journal of Medical Library and Information Science 2014;(5):59-61
The characteristics of medical and health literature novel assessment in institutions of armed forces were described from the secrecy of projects for literature novelty assessment , the limitations of consignee institution , and the non-profitability of literature novelty assessment agency .The major problems of medical and health literature novel assessment in institutions of armed forces were elaborated in terms of the literacy, instability, competency and knowledge limitation of literature novel assessment staff with suggestions put forward for their solution such as strengthening the construction of talent team, joint development and sharing of resources.
3.Effects of vasopressin and adrenaline on cerebral resuscitation in rats undergone cardiopulmonary resuscitation
Chinese Journal of Emergency Medicine 2011;20(3):277-280
Objective To compare the effects of vasopressin and adrenaline on cerebral resuscitation in rats. Method Sixty male SD rats were used to set the animal model of cardiac arrest and were randomly (random number) divided into 4 groups (n = 15/group): sham operation group (sham-gro), negative control group (neg-gro), vasopressin group (vas-gro) and adrenaline group (adr-gro). Blood pressure was recorded, and brain tissue samples were obtained. Results There was no significant difference in the recovery rate between vas-gro and adr-gro 30 min after resuscitation (P <0.05). The mean blood pressure in vasgro was higher than that in adr-gro within 30 min (1,2, 5, 10, 20, 30 min) after restoration of spontaneous circulation. The measured MDA, SOD and GSH were significantly different (P < 0.05) between each two groups among vas-gro, sham-gro and adr-gro. Conclusions The recovery rate was similar between vasopressin group and adrenaline group during cardiopulmonary resuscitation in rats. However, vasopressin can to maintain the mean arterial pressure at a higher level after resuscitation, which can the increase the cerebral perfusion and reduce brain cell damage.
4.Effects of Maca on kidney mitochondrial respiratory function and anti-aging capabilities in aged rats after exhausted exercise
Chinese Journal of Tissue Engineering Research 2016;20(18):2711-2716
BACKGROUND: Studies have shown that Maca can enhance immune cel function, improve mitochondrial respiratory chain enzymes, and play a role in anti-oxidation and anti-aging.
OBJECTIVE: To observe Maca effects on kidney mitochondrial respiratory function and anti-aging capabilities in elderly rats after exhausted exercise.
METHODS: 10-month-old elderly rats were intragastrical y administrated Maca powder 5 g/kg, once a day, and did treadmil exercise, 5 days in a week. Rats were randomly divided into control group, Maca group and training group and Maca+training group. At 6 weeks after training, rats in each group did exhausted exercise (35 m/min), and immediately received intraperitoneal injection of 2% sodium pentobarbital. The kidney was obtained, and mitochondria were extracted by differential centrifugation. A spectrophotometer was used to measure mitochondrial respiratory chain activity.
RESULTS AND CONCLUSION: (1) Mitochondrial respiratory chain enzyme and antioxidant enzyme activity: mitochondrial respiratory chain enzyme I-III, superoxide dismutase and glutathione peroxidase activities were higher in the Maca+training group than in the control group, Maca group and training group (P < 0.05 or P < 0.01), but malondialdehyde content was lower (P < 0.05 or P < 0.01). (2) Results suggested that the combination of supplement Maca and incremental exercise can improve mitochondrial respiratory function and delay aging in the kidney of aged rats after exhausted exercise. Moreover, supplemented Maca and incremental exercise have a synergistic effect.
5.Effects of Hormone Replacement Therapy and Sport Walk with Weight on Serum Lipid and Bone Mineral Density in Postmenopausal Women
Chinese Journal of Rehabilitation Theory and Practice 2008;14(10):974-976
Objective To explore the effects of estrogen,sport walking with weight and estrogen plus sport walk on serum lipid,bone metabolism and bone mineral density(BMD) in postmenopausal women.Methods 52 postmenopausal women were divided into the hormone replacement therapy(HRT) group(n=12),sport walking with weight group(Sp group,n=14),HRT + Sp group(n=12) and control group(n=14).HRT group took compound nylestriol,Sp group took sport walking with 5 kg weight and exercise intensity was from 60% to 80% VO2max,HRT+Sp group received two treatments as HRT group and Sp group.The experimental duration consisted of six months.Results The total cholesterol(TC),TC/high density lipoprotein cholesterol(HDL-C),alkaline phosphatase(APL) and urine calcium(Ca)/creatinine(Cr) were markedly lower in three experimental groups than the control group and before experiment(P<0.05 or P<0.01),HDL-C in Sp and HRT+Sp groups were markedly higher than the control group and before experiment(P<0.05),BMD of spine(L2~L4) and left trochanter in three experimental groups were markedly higher than the control group(P<0.01) and before experiment(P<0.0).Conclusion Both estrogen replacement therapy and sport walking with weight effectively improve serum lipid,prevent and reverse osteoporosis induced by menopause in women.
8.Effect of pravastatin on cardiac function and serum C-reactive protein levels in patients with chronic heart failure
Chinese Journal of Primary Medicine and Pharmacy 2008;15(5):740-741
Objective To study the effect of pravastatin on cardiac function and serum C-reactive protein (CRP) levels in patients with chronic heart failure (CHF). Methods 90 patients with CHF were randomly divided into pravastatin group (n=45) and control group (n=45). Pravastatin 40mg/d was administered in addition to the routine treatment for pravastatin group; the control group was received the routine treatment. All patients with CHF were examined serum CRP levels, LVEF at pretherapy and 3 months by ultrasonic cardiogram. Results At 3 months C-reactive protein levels were degraded in varying degree, and the serum CRP levels in pravastatin group was significantly lower than that in control group [(15.47±9.83)mg/L vs (20.31±7.15)mg/L](P<0.05), LVEF was significantly higher than that in control group[(45.70±7.01)% vs (38.34±5.31)%](P<0.05); the serum CRP levels was positively related to LVEF (r=-0.495,P<0.05). Conclusion Pravastatin may improve the prognosis in patients with CHF, and can be used as a sensitive index for pravastatin treatment of CHF.
9.Ezrin and tumor metastasis
Journal of International Oncology 2010;37(3):170-172
Ezrin is a member of ezrin-radixin-moesin(ERM)family acting as correlationship between plasma membrane and cytoskeleton,which plays an important role in maintaining shape,polarity,and movement as well as signal transduction of cells.The recent studies indicate that Ezrin abnormally overexpresses in majority of tumor cells,which has close relationship with carcinogenesis,invading and metastasis of tumor cells.
10.Cell competition and cancer
Journal of International Oncology 2010;37(1):34-37
Cell competition is a phenomenon that the expansion of superior cells at the expense of surrounding inferior cells.It makes sense as a mechanism to maximize tissue fitness and optimize organ function.However,disadjust cell competition may also result in proliferation of abnormal cells.If such a cellular activity in model organisms(such as D.melanogaster)does exist in human,it might help to understand the early events of carcinogenesis and explain some pathological findings.It could be useful for early diagnosis and therapy of cancer.