Objective To explore particularity of the diagnosis and treatment with massive bilateral chronic subdural hematoma (BCSDH) in elders.Method The clinical data of 25 elders with BCSDH treated in our hospital from 2007 to 2011 were analyzed retrospectively.All patients were examined with computerized tomography (CT) of 25 patients through the bilateral trephined hole.Results Twenty-four patients recovered better,the symptom significantly improved.After operative 1 month,14 patients? hematoma disappear,6 patents only had little bilateral subdural effusion,4 patents only had little unilateral subdural effusion.One patient appeared massive subdural effusion on the second day after operation,the familiality gave up therapy,and the patient was dead.Conclusion CT scanning should be taken before you make correct diagnisis.Bilateral single twist-drill craniostomy with irrigation and drainage is a chief method to massive BCSDH.

Biomedical Research ; Humans ; Integrative Medicine ; Medicine, Chinese Traditional

Aged ; Apraxias ; physiopathology ; Gait Apraxia ; physiopathology ; Humans ; Parkinson Disease ; diagnosis ; physiopathology

Humans ; Rectal Fistula ; surgery ; therapy

Objective To observe inhibitory effects of Ginsenoside on the proliferation cultured stem cells of human rectal carcinoma in vitro.Methods Tumor stem cells of rectal carcinoma in human were cultured in vitro and divided into saline water group,reltitrexed group(3mg/mL),and Ginsenoside(25μg/mL)plus reltitrexed(3mg/mL) group,with dosage of qd and for 2 weeks.Cells growth was observed under the microscope,and immunofluorescence staining was used to detect CD +133 expression of rectal carcinoma cells.MTT colorimetric method was taken to measure inhibitory of Ginsenoside on proliferation of tumor stem cells of rectal carcinoma.Apoptosis of tumor stem cells of rec-tal carcinoma lead by Ginsenoside was observed by DAPI staining.Results Part of cells were growing up like ball and CD +133 immunofluorescence staining was positive.Inhibitory role of Ginsenoside plus reltitrexed on CD +133 cells of rectal carcinoma appeared on the first day,which was bigger than that of retitrexed by MTT method (P =0.03).Com-pared with the retitrexed group,Gisenoside combined with reltitrexed reduced CD +133 cells expression of rectal carcino-ma,in which optical density and area density of CD +133 cells were obviously decreased with statistical significance (P =0.007,P =0.006,respectively).Conclusion Gisenoside plays the remarkably inhibitory role on proliferation of CD +133 cells of rectal carcinoma.

Objective To explore inhibitory effects of ginsenoside on the proliferation of human thyroid canc-er SW579 cells in vitro and expression of C -myc and Bcl -2 protein.Methods Human thyroid cancer SW579 cells were cultured according to conventional method.The study was divided into the control group and ginsenoside group (20,40,8ug/mL).Inhibitory role of ginsenoside on proliferation of SW579 cells was detected by MTT assay.Western-blot method was used to determine expression levels of C -myc and Bcl -2 protein in different group.Results The inhibition rates of 20,40,80μg/mL ginsenoside to SW579 thyroid carcinoma cell were 22.35%,51.76% and 68.24% respectively.Which meaned ginsenoside had obvious inhibitory effect compared with the control group(P <0.01),and inhibition increased with the increase of solubility(P <0.01).C -myc and Bcl -2 protein were reduced progressively in place with the increase of ginsenoside concentration by Western -Blot analysis (P <0.01 ).Conclusion Gisenoside may play the inhibitory role on proliferation of human thyroid cancer SW579 cells in vitro, and its mechanism may be related with down -regulation of C -myc and Bcl -2 protein.

0.2).The lymphocyte counts of the KD area grain group and the group of the KD area grain supplemented with Se were lower than that of the non-KD area grain group, and the CIC level and the hepatic Se content were much lower in the group of the KD area grain than in the other groups (p

According to the concept of sagittal spinal balance, the alternating curves of cervical and lumbar lordosis and thoracic and sacral kyphosis enable the head to be positioned over the trunk and pelvis. But the sagittal imbalance represents departure from this ideal form. Cervical kyphosis may represent the most disabling of these imbalances, for it can cause pain, postural difficulties, or neurologic deficit. A summary and discussion is reviewed regarding the anatomy, biomechanics, etiology, clinical presentation, laboratory examination and treatment of this condition.

The in-stent restenosis is one of the main complications in coronary artherosclerotic heart disease patients after PTCA and PCI.How to prevent it remains one of the most important projects in intervention therapy.In this paper,the preventive role of intravenous ultrasound and drug eluting stent were reviewed.

OBJECTIVE:To investigate the characteristics and regularity of adverse drug reaction (ADR) in a third grade class A hospital,and to provide reference for rational drug use in clinic. METHODS:A total of 813 cases of ADR reported to Na-tional ADR Monitoring by the hospital during 2013-2015 were summarized and analyzed retrospectively in terms of age,gender,route of administration,drug type,organs or systems involved in ADR,clinical manifestation and outcome. RESULTS:Among 813 cases of ADR,there were 391 male (48.09%) and 422 female (51.91%). Patients aged more than 60 were with high inci-dence of ADR,involving 347 cases(42.68%). Among routes of administration,most ADR cases were caused by intravenous ad-ministration,involving 747 cases (91.88%). Among all drug types,the number of ADR cases caused by anti-infective drugs was the most,involving 382 cases(46.99%);cephalosporins took up the highest proportion,being 38.22%(146 cases). Organs or sys-tems involved in ADR were mainly skin and its appendants,involving 434 cases (53.38%). CONCLUSIONS:ADR monitoring should be strengthened for elderly patients receiving anti-infective drugs intravenously so as to reduce the occurrence of ADR and guarantee medication safety.