1.Exploration of the mode for measurement and evaluation of nurses'occupational diathesis in employment systemed
Journal of Medical Postgraduates 2004;0(01):-
Objective:Under the background that the army hospitals need to employ civilian nurses in a large quantity,we try to grope a scientific,objective method to choose the nurse who matches post.Methods:Referring to related data and the ritual of talented person evaluation,we chose the evaluation methods including paper test,computer test,personal interview and data integration;arranged the steps of planning,assigning the weight,performing evaluation,integrating the test results,and tracking for feedback;in order to form the mode to test the employed nurses' occupational diathesis.Results:We fulfilled a series of scales for mood and hobby,weight score,quality structure,evaluation method comparison and nurse's professional quality evaluation,etc,and determined the evaluation methods and procedures.Conclusion:Evaluating more than 100 nurses who are newly employed using this new mode,the result demonstrates that this evaluation mode can be easily operated,and is a guide in employing quantities of professional nurses for a hospital.
2.The clinical significance of central electric fetal monitoringfor ante-partum observation
Journal of Chongqing Medical University 2003;0(06):-
Objective:To study the clinical significance of central electric-fetal monitoring system for ante-partum observation and measurement.Methods:The experimental group (253 pregnant women who delivered in our hospital from January,2001 to August,2003) was monitored with the central electric fetal monitoring system.The control group (250 pregnant women who delivered the children in our hospital from July,1998 to September,2000) was not monitered with this system.Then,the results of fetal monitoring and the outcome of prenatal fetuses of the two groups were compared and analyzed.Results:The rate of abnormal FHR was markedly higher in experiment group(30.8%) than in the control group(17.2%),and the rate of variable deceleration in abnormal graph was markedly higher in the experimental group (28.8%) than in the control group (12.4%).There was a significant difference is significant between the two groups.The incidence of asphyxia among newborns was lower in the experimental group (4%) than in the control group (8.4%),and the difference is significant between the two groups.However,there was no significant difference in the rate of cesarean delivery and Simpson forceps delivery between the two groups.Conclusion:Ante-partum monitoring assisted by central electric-fetal monitoring system can improve the prenatal prognosis and increase the rate of cesarean delivery.
3.Investigation and analysis of sexual concept and sex status of pregnant women
Journal of Chongqing Medical University 1986;0(02):-
Objective:To investigate the sexual concept and sex status of pregnant women so as to instruct pregnant health care and improve living quality.Methods:112 random sample candidates who have mature fetus for delivery in hospital were chosen to investigate and analyze by means of self-edited questionnaires and Eysenck protracted sexual latitude scale test.Results:Both sex frequency and sex continuing time of pregnant women reduced remarkably;their knowledge on sex related to pregnancy was generally poor;average value of Eysenck protracted sexual latitude scale test was 5.25,lying below the average points;professionals and individual professionals have statistics differences in occupation team;the single-mode of sexual intercourse in the sex of pregnant women has the highest percentage.Conclusion:Pregnant women lack the related health care knowledge on sex,and their concept of sex is comparatively conservative,so they can not enjoy full sex and need further improvement.
4.Construction and primary characterization of cDNA expression library of Humulus pollen
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(04):-
Objective To construct a cDNA expression library of Humulus pollen and provide the basis for screening the major allergenic components and producing recombinant allergen of Humulus pollen.Methods Verdure Humulus pollen were collected and preserved in liquid nitrogen after being sift out.Total RNA was extracted from the Humulus pollen with trizol reagent,and cDNA was synthesized by RT-PCR with purified total RNA.Then the cDNA was digested by SfiⅠ and the fragments smaller than 400bp were removed by chroma spin-400 column,and the fragments longer than 400bp were ligated with ?TripIEx2 Vector.The library was packaged in vitro and a small portion of packaged phage was used to infect E.coli XL1-Blue MRF′ for titration.The diversity of the library and the length of the inserted fragments were analyzed by PCR.Results The cDNA expression library contained 5?10~(5) recombinants and the percentage of recombination was 90%.The average length of inserted cDNA fragments was about 1.02kb.Conclusion The constructed cDNA expression library contains appropriate contents and sizes of cDNA fragments and is qualified for screening target cDNA clone.
5.Laparoscopic Sphincter Preserving Surgery for Ultra Low Rectal Cancer:Report of 108 Cases
Chinese Journal of Minimally Invasive Surgery 2016;16(4):294-296
Objective To explore advantages of laparoscopic sphincter preserving surgery for ultra low rectal cancer . Methods From April 2006 to January 2015, we performed laparoscopic sphincter preserving surgery in 108 cases of ultra-low rectal cancer.After laparoscopic mesorectal resection and lymph node dissection were completed , transection of the rectum was performed with the Endo-GIA at 2 cm from the lower margin of the tumor .The right lower abdomen main operation port was expanded to remove the lesion and introduce the stapler base .The proximal colon was returned and the pneumoperitoneum was re-established .A colorectal end-to-end anastomosis was conducted through the anus by using a carliber 29 circular stapler . Results Laparoscopic operation was successfully accomplished in all the 108 cases.No conversion to open surgery was required .No operative mortality was encountered . The operation time was 68 -145 min ( mean, 104 min ) , the intraoperative blood loss was 10 -100 ml ( mean, 40 ml ) , the postoperative flatus time was 1-3.5 d (mean, 2.3 d), and the number of removed lymph nodes was 8-37 (mean, 12.5).There were 98 patients followed up for 6-62 months (mean, 24.6 months).No tumor metastasis or recurrence was found . Conclusion Laparoscopic total mesorectal excision of ultra low sphincter preserving operation is feasible .
6.Transcription factor Forkhead-box A1 and breast cancer.
Chinese Journal of Pathology 2010;39(2):136-139
Animals
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Antineoplastic Agents
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therapeutic use
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Breast Neoplasms
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drug therapy
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genetics
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metabolism
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Cyclin-Dependent Kinase Inhibitor p27
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Fenretinide
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therapeutic use
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Hepatocyte Nuclear Factor 3-alpha
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genetics
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metabolism
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Humans
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Intracellular Signaling Peptides and Proteins
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metabolism
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Prognosis
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Receptors, Estrogen
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metabolism
7.S100 proteins and prostate cancer
Journal of International Oncology 2012;(11):870-872
The S100 proteins are a multi-gene calcium-binding family,which are differently expressed in a variety of tumors.It is found to be associated with tumor invasion and metastasis.As a tumor-associated biomarkers,unraveling the relationship between S100 and prostate cancer progression as well as molecular mechanisms,would provide an important basis for the clinical diagnosis and therapeutic monitoring.
8.EXPRESSION CHANGES OF ESTROGEN RECEPTOR IN RAT BRAIN OF DIFFERENT AGES
Acta Anatomica Sinica 1953;0(01):-
Objective To investigate the estrogen receptor expression character on neurons and glial cells of rat at different ages. Methods Brain sections from normal and injured rats of different ages were chosen to observe the ER immunohistochemistry reaction in cerebrum. Results To compare with normal young rat group,the neurons in hippocampus dentate gyrus of normal aged rat group expressed much less estrogen receptors.There were many ER-positive glial cells appearing in hippocampus of brain injured was rat group,and the positive strain of young injured was much stronger than that of aged rat group.Conclusion The decrease of ER on neurons in dentate gyrus makes the aged more apt to neurodegeneration.The young rats may better utilize the neuroprotection of estrogen against injuries by increasing the amount of ER on glial cells.
9.Clinical Analysis of Comprehensive Therapy with Database in Advanced Non-small Cell Lung Cancer
Journal of Medical Research 2006;0(05):-
Objective To analyze the effect of on comprehensive therapy advanced non-small cell lung cancer,and summarize the clinical experience.Methods Based on the comprehensive therapy characteristic,we designed a clinic cases analysis database using the SQL sever database technique.Results In the 102 patients with advanced non-small cell lung cancer in the Xiyuan Hospital,the mean survival period was 11.5 months and the 1 year survival rate was 37.5%.The weight was stable and KPS was increased.There was significant difference in the improvement of mental weariness and hypodynamia,deficient breath and indolence,cough,abundant sputum,pain,anorexia,sputum mixed with blood,constipation,abdominal diarrhea and distention(P
10.Dopaminergic modulation of neuronal activity in the striatum
Chinese Pharmacological Bulletin 1987;0(01):-
The striatum is involved in diverse behaviors which depend on intact dopaminergic innervation. Recent electrophysiological studies have revealed that dopamine alters both voltage dependent conductances and synaptic transmission, resulting in state dependent modulation of target cells. This review makes clear predictions about how dopamine should alter the responsiveness of striatal neurons to extrinsic excitatory synaptic activity.