1.Clinical Significance of Serum Cardiac Troponin in Patients with Dilated Cardiomyopathy
li-ming, CAO ; yu-ming, QIN ; feng-ming, WANG
Journal of Applied Clinical Pediatrics 2004;0(07):-
Objective To observe the serum cardiac troponin I (cTnI) level and to analysis the relations between the serum cTnI level and prognosis in patients with dilated cardiomyopathy (DCM) and Cardiac Dysfunction.Methods Serum cardiac cTnI level was measured by enzyme-linked immunosorbant assay. Results The serum cTnI level in DCM patients with class IV cardiac function (0.53 ?0.31) ?g/L was significantly higher than in DCM patients with class Ⅲ cardiac function (0.45?0.27) ?g/L.There was significantly difference in serum cTnI levels between DCM patients with class Ⅲ cardiac function and DCM patients with class Ⅱ cardiac function(0.29?0.27) ?g/L.Conclusion The higher serum cTnI level is correlated with the severity of cardiac function and may be useful for evaluating prognosis in patients with DCM.
2.Effects of SV heat-resisting protein on the microglial cells in MPTP-treated mice.
Sheng-Ming YIN ; De-Qin YU ; Ning AN
Chinese Journal of Applied Physiology 2009;25(1):79-90
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
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Animals
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Female
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MPTP Poisoning
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drug therapy
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pathology
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physiopathology
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Male
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Materia Medica
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therapeutic use
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Mice
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Mice, Inbred C57BL
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Microglia
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drug effects
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pathology
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Parkinson Disease, Secondary
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chemically induced
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drug therapy
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physiopathology
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Scorpion Venoms
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chemistry
3.An analysis of causes for misdiagnosis of 112 cases with tuberculosis in children.
Man TIAN ; Ming QIN ; De-yu ZHAO
Chinese Journal of Pediatrics 2007;45(6):460-461
Antitubercular Agents
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therapeutic use
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Child
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Child, Preschool
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Diagnostic Errors
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Female
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Fever
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etiology
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Humans
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Infant
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Male
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Pediatrics
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Tuberculosis
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drug therapy
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microbiology
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physiopathology
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X-Ray Film
7.Cardiac troponin I is increased after interventional closure of congenital heart diseases in children.
Yu-ming QIN ; Da-wei WANG ; Shi-wei YANG
Chinese Journal of Pediatrics 2005;43(12):935-936
Child
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Child, Preschool
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Female
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Heart Defects, Congenital
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metabolism
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Humans
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Male
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Troponin I
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metabolism
10.Effects of Coincident Infection on Treatment Response and Coronary Artery Lesion Outcome in Children with Kawasaki Disease
yan-qin, CUI ; ming-hua, YU ; ping, HUANG ; li, ZHANG
Journal of Applied Clinical Pediatrics 2006;0(15):-
Objective To explore the effects of coincident infection on treatment response and coronary artery lesion (CAL) outcome in children with Kawasaki disease(KD).Methods A retrospective study of 141 children diagnosed on KD between Jul.2005 and Dec.2006 were performed.Standardized clinical assessments,laboratory examinations microbiology test results plus treatment regimens were reviewed.CAL were visualized by using echocardiography.Infectious agents positive (INF+) and negative (INF-) groups were identified,and clinical assessments,laboratory and treatment data were analyzed.Results 1.Concurrent infections:41%(58/141) of children had one of above confirmed infection at KD diagnosis.2.Treatment response:the presence of infection did not alter the response to treatment with intravenous immunoglobulin (IVIG),with resolution of fever within 72 h in 85% (120/141) children after 1 dose of IVIG (2 g/kg) together with aspirin administration regardless of present or absent infection.3.CAL outcome:in total,56.0% (79/141) of children developed CAL at the time of diagnosis,involving dilatation (91.1%,72/79 cases) and aneurysm (8.9%,7/79 cases),and no giant aneurysm was found.Most CAL were recovered within 1 year after treatment.Incidence of aneurysm in INF+ group was significantly higher than that in INF-group (P=0.019).Conclusions Coincident infection would not affect on the clinical assessment,laboratory test results and treatment response to IVIG in children with KD,but would result in higher risk of serious CAL.Therefore,children with infection at diagnosis on KD will not only accept active treatment in acute phase,but also insist on convalescent care and follow-up visit.