Objective To find out the development of health education project on iodine deficiency disorders (IDD) in 2013 and evaluate the intervention effect.Methods According to the local situation,in 21 provinces,644 counties with more serious conditions of the disease or in the remote areas were selected as the project counties.Three towns in each county were selected,the health educational activities were carried out among the grade 4-6 students in the central primary school of each town.Three villages in each town were selected to carry out community health education.Before and after the activities,questionnaire surveys on the knowledge of IDD were conducted in each town including 30 students from one class of grade 5 in the primary school and 15 housewives near the primary school were selected randomly.Results After health education,the awareness rates of knowledge on IDD in the students and the housewives were 94.35％ (57 087/60 506) and 93.12％ (30 325/32 566).Compared with those baseline investigation 74.31％ (44 768/60 245) and 75.89％ (24 785/32 659),the differences were statistically significant (x2 =9 183.92,3 695.21,all P ＜ 0.01).Before health education,the awareness rates of knowledge of IDD in the students were lower than those of the housewives (x2 =28.11,P ＜ 0.01).After health education,the awareness rates of knowledge of IDD in the students were higher than those of the housewives (x2 =55.89,P ＜ 0.01).Conclusions The awareness rates of knowledge on IDD in the students and housewives are increased significantly after the health educational activities.The results show that health education project is effective in prevention and control of IDD.

Autophagy is the cytoplasm and organelles of eukaryotic cells through degradation of itself,aself digest,a series of biochemical process is a kind of programmed cell death,its main function is to remove and degrade its damaged organelles and redundant biological macromolecules,and use the degradation products provide energy,reconstruction and cellular structure,in the steady state of cell and cell life activities play an important role.In recent years,autophagy in glomerular cells play a role of regulation and control have become the focus in the confrontation podocyte damage,including Beclin-1 autophagy related genes in the role of autophagy regulation has caused wide public concern.This article chooses of Beclin-1 in sertoli cell autophagy related research in the role of regulation are reviewed.

Increasing evidence has proved that phenotypic changes occured in residential renal cells during the process of renal diseases. The phenotypic change of mesangial cell plays a key role in the development of glomerular sclerosis, while the phenotypic changes of tubulo-interstitial cells have close relationship with the progress of interstitial fibrosis. Understandings of these phenotypic changes and their regulations may help us know better of the mechanism of renal diseases and find out ways to block the disease development.

Acupuncture Therapy ; Adolescent ; Adult ; Back Pain ; therapy ; Female ; Humans ; Male ; Middle Aged ; Spinal Cord Injuries ; therapy ; Young Adult

OBJECTIVETo investigate the long-time effects of nylon fixation at the internal and external canthus combined with skin graft for recurrent lower eyelids ectropion.

METHODSUnder local anesthesia, the cicatricial contraction was released to repostion the lower eyelid. Then nylon thread was implanted in the fascial tissue at the upper margin of tarsus and was fixed on the periosteum at the internal and external canthus. The skin graft was applied on the wound of lower eyelids.

RESULTS12 patients with lower eyelids ectropion at 19 sides were treated with primary healing. The patients were followed up for 6-24 months. All cases were satisfied with functional and cosmetic results. No complication and no recurrence happened.

CONCLUSIONSThe technique of nylon fixation at the internal and external canthus combined with skin graft is an effective method for recurrent lower eyelids ectropion.

Ectropion ; surgery ; Eyelids ; surgery ; Fasciotomy ; Humans ; Nylons ; Periosteum ; Skin Transplantation ; methods

Objective To establish the HPLC fingerprint analysis method for the quality control of Flos Daturae. Methods Column:Zorbax C18 (4.6 mm?250 mm, 5 ?m);Mobile phase:0.07 mol/L NaPO4 (adjust pH to 6.0 with phosphatic acid, including 17.5 mmol Soldium dodecyi Sulphate)-Acetotrile (2∶1). Flow rate was 0.8 mL/min and detection wave length was 216 nm. Results The repetition and precision of the method was good. There was obvious difference between South and North Flos Daturae based on the results of cluster and similarity analysis. Conclusion The method can control the quality of Flos Daturae effectively.

OBJECTIVE To know the use of antibiotics in fever clinic of our hospital,and analyze whether it is reasonable.METHODS The situation was reviewed and analyzed that antibiotics were used for patients in fever clinic during the 4th quarter of 2005 by the doctor registry,original prescriptions,and data records of laboratory.RESULTS There were some unreadable aspects in the choice of antibiotics,the using method,drug combination etc in fever clinic of our hospital.CONCLUSIONS Fever clinic should enhance supervision management of the proper use of antibiotics.

Objective To study the clinical applicated value of thrombin injection in the treatment of 30 pa-tients with femoral artery pseudo-aneurysm guided by color Doppler ultrasound .Methods 60 patients with femoral artery pseudoaneurysm were selected as the observation group ,according to a random number table ,they were divided into A group and B group ,A group was treated with ultrasound guided compression therapy ,B group was treated with ultrasound guided thrombin injection;also early femoral artery pseudoaneurysm OK conventional surgical methods for the treatment of 30 patients in the control group .The statistical method of ultrasound-guided two treatment success rate,thrombus formation time and observation group and control group success rate and complication rate .Results Ultrasound-guided compression therapy for 30 cases,14 cases of successful initial oppression ,oppression success rate of 46.6%for the first time,repeat oppression the success rate of 87.5%.Two cases were cured after thrombin injec-tion therapy .B group was treated with thrombin injection of endovascular ,24 cases in 30 cases were cured after first injection,the first injection success rate of 80.0%;all cases were cured after two injections .Thrombus formation time was(0.30 ±0.05)min.treatment success rates for the first time and thrombus formation time were significantly differ-ent(all P<0.01).30 cases were cured by surgical treatment .Postoperative complication rate was 6.7%.The first treatment success rates and complication rates of the two groups were significantly different (P<0.05).The total suc-cess rates of the observation group and the control group were 100%respectively .The difference was not statistically significant(P>0.05).Compared with the observation group ,the incidence rate of postoperative complications of con-trol group was 6.7%(P>0.05).Conclusion In the femoral artery pseudoaneurysm positioning and puncture thera-py,Color Doppler ultrasound-guided thrombin may provide a reliable basis , thrombosis treatment success rate and thrombus formation time were significantly better than that of ultrasound-guided compression therapy ,which has broad application prospects .

OBJECTIVE To strengthen the hospital supply Division standardized management and prevent the pathogenic microorganism dissemination effectively and safeguard the human health.METHODS Strengthening the vocational study,improving personnel′s knowledge level,formulating control system,strengthening detail and flow management and adopting the effective monitoring method all were the main measures.RESULTS The results were to guarantee the aseptic material quality,and prevent the occurreance of hospital Ainfection.CONCLUSIONS The scientific and effective management measures make our supply division a good quality management institution,with the programming the materiol processing and the standardizing the disinfection and antisepsis.

Dry eye is a common, highly prevalent and multifactorial ocular disease.Severe dry eye not only has a serious impact on the patient's work performance and quality of life, but also increases the risk of other ocular disease complications.Due to its complex pathogenesis and prolonged treatment cycle, dry eye has become an important social and public health problem.Traditional dry eye drugs can usually alleviate, but not completely eliminate, the symptoms of dry eye, and are far from meeting current clinical demands.Newly marketed domestic and foreign anti-inflammatory drugs that inhibit T cell function as well as drugs that promote tear secretion represent, to some extent, the rapid progress of dry eye drug research.Even so, the overall state of clinical dry eye management has not been significantly improved.Dry eye treatment still faces great challenges; a huge gap exists between clinical needs and the development of new drugs.Insightful research on the pathogenesis of dry eye is the basis for identifying new pharmatheutical targets.Progress in the research and development of dry eye drugs brings about new options for treatment strategies.Ophthalmologists should keep updated to the research progress in dry eye and to the mechanism of actions of new drugs in order to better serve dry eye patients.