1.Effects of bisoprolol on heart rate and heart rate variabirty in mild to moderate hypertension patients
Chinese Journal of Primary Medicine and Pharmacy 2006;0(01):-
0.05).Both SBP and DBP were declined significantly in both two groups(P0.05).Heart rate decreased from (81?9)b/min to (68?7)b/min in bisorpolol group.But there wasn't this effect in contrast group.It was superior to that of contrast group significantly too(P
4.Therapeutic Effects of Atomoxetine on Children with Attention Deficit Hyperactivity Disorder Comorbid Tic Disorder
yu-juan, ZHANG ; yu-feng, WANG
Journal of Applied Clinical Pediatrics 1993;0(03):-
Objective To explore the clinical effect of atomoxetine on children with attention deficit hyperactivity disorder(ADHD)comorbid tic disorder.Methods The children who met the criteria of Mental Disorders Diagnostic and Statistical Manual diagnostic criteria for ADHD and tic symptoms were given systematic atomoxetine titration reaching the optimum dose.ADHD and tic symptoms were evaluated with ADHD rating scale-Ⅳ(ADHD-RS-Ⅳ)for parents Yale Global Tic Severity Scale(YGTSS),respectively.Results Twenty children with ADHD comorbid tic disorder [17 male,3 female;age range 7.58-17.0 years,mean age(10.55?2.58)years] completing systemic titration was enrolled in the study,including 10 subjects with ADHD-inattentive type,9 mixed type,and 1 hyperactive/impulsive type.The mean optimal dose was(1.19?0.21)mg/(kg?d).The total score(12.65?9.08)scores,inattention score(7.45?4.75)scores and hyperactivity/impulsivity score(3.0)of ADHD-RS-Ⅳ decreased significantly post-treatment compared with pro-treatment(31.10?8.52,17.60?3.09,and 13.0 scores,respectively,P
5.Effects of early growth on postprandial metabolic responses and related diseases in adulthood
Ruijie YU ; Feng WANG ; Junjun WANG
Journal of Medical Postgraduates 2014;(6):639-642
Early growth is associated with later health outcomes including cardiovascular disease and type 2 diabetes.It has been suggested that these associations are mediated through classical risk factors , for example dyslipidemia .It has confirmed that post-prandial levels of many risk factors have been proposed to be more important than fasting levels in the initiation and progression of a -dulthood diseases .The studies about the effect of early growth on postprandial responses have attracted considerable attention .This re-view focuses on the relationship between early growth and postprandial responses , and the role of both in adulthood diseases , aiming to further discuss the relationship and possible mechanism between early growth and later diseases .
7.Clinical features of post-ictal headache in patients with epilepsy and the risk factors
Yinzhou WANG ; Feng YU ; Junjian ZHANG
Chinese Journal of Practical Internal Medicine 2001;0(10):-
Objective To determine the clinical characteristics of post ictal headache (PIH) and clinical risk factors associated with the occurrence of PIH in patients with localization related epilepsy.Methods The subjects were 47 patients with temporal lobe epilepsy (TLE),21 patients with occipital lobe epilepsy (OLE),and 29 patients with frontal lobe epilepsy (FLE).The subjects were directly asked whether headaches occurred just after seizures and its characteristics.Results The characteristics of PIH were:throbbing quality,which was exacerbated by coughing,vomiting,bending,and sudden head movement,accompanied by photophobia,phonophobia,and relieved by sleep.The incidence of PIH was 21 3% for TLE,61 9% for OLE,and 41 4% for FLE.The risk of PIH was significantly higher for OLE than for TLE or FLE,and for patients with generalized tonic clonic seizures.Younger onset age of epilepsy was also a risk factor for PIH.Conclusions PIH possess some characteristics similar to migraine.The occurrence of PIH may be related to the region of epileptic focus and the region of the spread of epileptic discharges.
8.Analysis of the cyanide in biological samples by using HS
Shizhen FENG ; Zhongshan YU ; Fanglin WANG
Chinese Journal of Forensic Medicine 1988;0(04):-
Objective to establish a method used for qualitative and quantitative determination of the cyanide in biological samples by using HS/GC/ECD. Method C1CN was formed as the choramines-T derivative through reaction of the potassium cyanide with chloramines-T and then was analyzed by GC/ ECD/HS. Results if 0.2ug potassium cyanide was added to 1ml blood sample, the recovery was 84.6% and RSD was 6.39%. If 0.5ug potassium cyanide was added to 1. 0g liver, the recovery was 67.3 % and RSD was 5.05%. The detection limit of blood sample was 5ng/ml. Conclusion This method can be used for analyzing the cyanide in biological samples quantitatively.
9.Modified Brisson technique for concealed penis in children
Junbin GUO ; Yu ZHONG ; Feng WANG
Chinese Journal of Applied Clinical Pediatrics 2017;32(11):825-827
Objective To investigate the corrective effect of modified Brisson technique to treat concealed penis in children.Methods From July 2014 to July 2016,selected 12 patients (3-10 years old,mean 7.2 years old) with concealed penis were surgically treated with the modified Brisson technique in the Second Affiliated Hospital of Nanjing Medical University.Their clinical manifestations included the penis buried below the surface of prepubic skin which can be palpated and visualized through pushing the skin around the penis to the pubis and the short foreskin which was not attached to the penile corpus cavernosum.Patients with other conditions such as obesity and penial agenesis that caused buried penis were excluded from the study.The modified Brisson technique consisted of 4 steps.Ventral incision was used to gradually slit the narrow ring of the prepuce and to expose the glans followed by circumfe-rential inner foreskin incision made below the coronary sulcus of penis then the foreskin stripping released the corpus cavernosum.Finally the skin coverage was accomplished by posthioplasty.The operation time,blood loss,complications,postoperative treatments and followed-ups were retrospectively analyzed.Results For all the 12 patients,the operations were successful,lasting 40 to 60 minutes.The bleeding was about 5 to 10 mL and there was no operation-related complications like bleeding and infection of incision.Satisfactory cosmetic outcomes were obtained without retraction and the scars were similar to those of circumcision.All patients had penile lymphedema postoperatively which disappeared within 6 months after operation.Follow-up ranged from 6 months to 1 year,and there were no complications like skin necrosis and contracture or voiding difficulty.Conclusions The modified Brisson technique for concealed penis repair is technically easy and safe.In addition,it provides a good cosmetic appearance,functional outcomes and excellent postoperative satisfaction grades.
10.Application of anti-angiogenesis therapy in the radiotherapy of esophageal cancer
Yue FENG ; Jingping YU ; Jianlin WANG
Journal of International Oncology 2017;44(6):468-471
Radiotherapy is the principle method of non-surgical treatment for esophageal cancer.The 5-year survival rate ranges from 20% to 40%.In recent years,the studies have found that anti-angiogenesis therapy can not only directly inhibit tumor nutritional intake,but also turn around tumor hypoxia by normalizing tumor vessels so as to enhance the radio-sensitivity of tumor ceils,which is expected to become an effective way to improve the curative effect of esophageal cancer radiotherapy.