Objective To observe the clinical curative effect of Xuezhikang maintaining treatment for senile hyperlipidemia.Methods According to the digital table,96 elderly patients with hyperlipidemia were selected and randomly divided into the three groups.The control group 1 with 32 cases took orally rosuvastatin before sleeping 10mg per time,1 time /day,12 weeks one treatment course.The control group 2 with 32 cases took orally Xuezhikang capsule before sleeping 0.6g 2 times/day,12 weeks one treatment course.The treatment group with 32 cases took first orally rosuvastatin before sleeping 10 mg/time,1 time /day for 4 weeks,then changed to use Xuezhikang capsule 0.6g 2 times/day for six weeks.The total treatment course was 12 weeks.Results After treatment,TC,TG,LDL-C in three groups all declined significantly and HDL-C increased.The curative effect was similar in treatment group and control group 1 with no statistical difference(P >0.05).Conclusion Xuezhikang has similar efficacy with rosuvastatin 10 mg/time in hyperlipidemia,and recommand Xuezhikang clinical use for its lower price.

Citrin deficiency,caused by mutations in SLC25A13,is an autosomal recessive genetic disorder with two age-related phenotypes:adult-oneset type Ⅱ citrullinemia and neonatal intrahepatic cholestasis.Recently,it has been found mostly in individuals of East Asian ancestry.In south China,there is a high mutation carrier frequency especially.There is still a lack of criteria for clinical or biochemical diagnosis of this disease,gene analysis is the main basis of the current diagnosis consequently.Surging number of case reports indicate that Citrin deficiency is not a self-limited disease.Early diagnosis and proper treatments may improve the prognosis.This paper focuses on the current researches in order to make further comprehensiom.

Objective: To study the effect of fish-oil fatty emulsion on immunity of post-operation patients with malignancy tumors.Methods: Forty-three post-operation patients with malignancy tumors were randomly divided into control group and study group and both groups were provided with parenteral nutrition treatment [104.6 kJ(25 kcal/kg)].Fish-oil fatty emulsion was given to the study group.The level of serum albumin,immunity function,jaundice index,aminotransferase,blood lipid and morbidity rate of infectious complications of the two groups were compared.Results: After five days of post-operation treatment,in the study group,the immunity function was significantly improved and morbidity rate of infectious complications declined.The levels of serum albumin,the blood lipid,jaundice index,and aminotransferase had no significant difference between the two groups.Conclution:Fish-oil fatty emulsion is beneficial to the immunity function and can emilsion decrease infectious complications of post-operation patients with malignancy tumors.

This article introduces concept of quality of work life and analyses main factors influencing quality of teachers'work life. In order to stabilize emotion of teachers and retain excellent teachers,we put forward the suggestions for improving and enhancing the quality of teachers'work life.

During the whole process of rescue operations,the teleconsultation vehicle has not only realized long-range consultation function but also played a vital important role in emergency communication,propagation,contaction,etc.Its manifestation tracks out some practical methods for the emergency rescue operation hereafter.

To meet with the new problems of curriculum design about prevention medicine field to undergraduate in medical college,based on our teaching practice,we tried to explore some teaching measures about fieldwork of health education,in term of updating teaching methods and skills so as to enhance our students' integrated quality,cultivate and bring up more and more capable new-pattern preventive medical students fit for the public requirements.

Objective To investigate the effects of Wuling Powder on insulin resistance of C57BL/6J mice induced by high lipid diet, and discuss the mechanism. Methods C57BL/6J mice were randomly divided into six groups:normal group, model group, rosiglitazone group, Wuling Powder in low, middle, and high dose groups, 10 mice per group. Besides the normal group, other five groups were fed with high fat and sugar diet, with a purpose to establish insulin resistance model. Normal group and model group were given pure water. Rosiglitazone group received a gavage with rosiglitazone of 0.75 mg/kg. Wuling Power low, middle, and high groups received gavage with Wuling Power of 1.23, 3.69, 11.07 g/kg, respectively, the does volume was 0.2 mL/10 g, once a day. The weight and abdominal girth were detected every week. At the end of the sixth week, mice were given 12-hour fasting, and their eyeball were taken for blood. The body weight, length, and fat in abdomen and both kidneys were detected. Paraffin section was made with HE staining. FPG and FINS of each group were detected. ISI and IRI were calculated, and TC and TG were detected. Results Compared with the model group, Wuling Powder can significantly reduce the body weight and abdominal girth of mice (P<0.01, P<0.001), improve liver fatty degeneration, lower the FPG, FINS, TCH, TG, IRI, and increase the ISI in mice (P<0.05, P<0.01). Conclusions Wuling Powder has the effect of preventing insulin resistance of C57BL/6J mice induced by high lipid diet.

OBJECTIVE:To establish a HPLC method for the determination of dolastron mesylate.METHODS:The sample was separated on Diamonsil C18 column.The mobile phase consisted of acetonitrile-water-1mol? L-1 ammonium formate(450∶ 440∶ 110)(pH=8.0 adjusted with trithylamine)with a flow rate of 1.0mL? min-1.The UV detection wavelength was set at 285nm and the sample size was 20? L.RESULTS:The linear range of dolasetron mesylate was 24～ 56? g? min-1(r=0.999 6),with average recovery at 99.7%(RSD=0.74%).CONCLUSION:The established is simple,sensitive and reproducible,and suitable for the quality control of dolasetron mesylate.

Objective Utilizing the characters of pyrrolidine dithiocarbamate known as a specific inhibitor of NF‐κB and imidapril known as a specific inhibitor of angiotensin converting enzyme ,this study was to initially investigate the relationship between NF‐κBp65 and AngⅡ during the process of myocardial ischemia reperfusion injury .Methods Rat models of myocardial ischemia reper‐fusion injury were successfully established .The observation point is 60 min of reperfusion after 30 min(I30 min R60 min ) ischemia ,the DNA activate of NF‐κBp65 was detected by ELISA ;the content of AngⅡ in blood plasma and cardiac were determined by radioim‐munoassay .We pretreated with pyrrolidine dithiocarbamate ,imidapril ,and both of them to observe changes of the same indexs .Re‐sults Compared with I30 min R60 min ,Pyrrolidine dithiocarbamate ,Imidapril and pyrrolidine dithiocarbamate add imidapril could all ob‐viously inhibit NF‐κBp65 activation and depress the content of Ang Ⅱ in blood plasm and cardiac ,the pyrrolidine dithiocarbamate add imidapril was most obviously .Conclusion During the process of myocardial ischemia‐reperfusion injury ,NF‐κBp65 had been activated ,and the content of Ang Ⅱ in blood plasm and cardiac had increased .NF‐κBp65 and AngⅡ could influence and promote each other during myocardial ischemia reperfusion injury .

Network management of health record is an important measure to realize the aim of equalization of the basic public health services.Nowadays,a lot of ethical hidden dangers have been left when most areas of our country doing the job of network management of health record,such as,violating the citizen rights of privacy and informed consent,impairing citizen rights of autonomy and health,lacking of balance mechanism between the individual interest and public benefit,and so on.In this paper,these phenomena are considered based on ethical rules,and suggestions centred around the improving of trust valuations between doctors and patients,information technology,medical moral education and the setting up of related laws for improvement have been provided.