Taking Cancer Hospital Affiliated to Southwest University as an example,the paper states the deployment of m-health network,and puts forward several wireless network optimization schemes such as wireless environment optimization,channel capacity improvement,code efficiency increase and user access restriction through clinical business traffic monitoring and data analysis.Through the result,this scheme can improve the performance of the wireless network effectively.

Objective To investigate on blood group serology of crossmatching incompatibility of blood donors in clinical hospi‐tals in Nanchong from 2010 to 2014 .Methods According to blood group serological test ,direct antiglobulin test (DAT ) was used for blood specimen with crossmatching incompatibility where donor was suspected as the causes ,at the same time irregular antibody was screened and identified .Results Among 77 returned blood specimens ,positive DAT were found in 43 cases ;while irregular an‐tibodies were found in 18 cases ,with anti‐M and anti‐E as the major ,followed by anti‐Lea and anti‐P1;and 16 cases did not find ab‐normality .Conclusion Causes of crossmatching incompatibility of blood donors in clinical hospitals in Nanchong are mastered through the survey ,to improve the safety level of clinical blood transfusion and avoid the waste of the blood .

Mast cells regulate inflammation and immunity.Experimentally induced abdominal aortic aneurysm in mast cells-deficient animals and animals treated with mast cells inhibitors demonstrate that mast cells are involved in the pathogenesis of abdominal aortic aneurysm via several different mechanisms.Mast cells-dependent activation of metalloproteinases and the renin-angiotensin system,contribution to smooth muscle cell apoptosis,and release of proteolytic enzymes are some key examples.Activated mast cells also contribute to neovascularization,inflammation,and atherosclerosis,all hallmarks of abdominal aortic aneurysm.Thus,we may envision that mast cells stabilizing agents,as well as leukotriene receptor antagonists and histamine receptor blockers already in clinical use for treatment of other diseases,could also be tested for their efficacy in treatment of abdominal aortic aneurysm.

Objective Explore the clinical value of ultrasonography in the diagnosis of skeletal muscle injury in the Achilles tendon .Methods Select visit from March 2016 to March 2017 period in orthopedic hospital 56 patients with Achil-les tendon injury , using a random number table group , the experimental group using diagnostic ultrasound skeletal muscles of the control group using diagnostic methods MIR , and ultimately by surgery as a diagnostic criteria between the two groups of patients with the diagnosis .Results Diagnostic accuracy rate of the experimental group were 96.42%.Skeletal muscle ul-trasound display achilles tendon rupture 12 patients , 6 patients with chronic Achilles tendon hyperplasia , swelling of the A-chilles tendon 6 patients, the diagnostic accuracy of the control group were 92.86%.Skeletal muscle ultrasound display A-chilles tendon rupture in 10 patients, 8 patients with chronic Achilles tendon hyperplasia , swelling of the Achilles tendon 3 patients.The results between the two groups of patients was statistically significant , that is P<0.05.Conclusion Ultra-sound in the diagnosis of skeletal muscle tendon injury in a significant clinical effect , but also has an affordable price , easy to operate and less damage to human advantage .It should be introduced .

Top-quality courses are a pace-setter and a symbolic banner in the construction of the academic courses, and will have an inestimable role in the promotion of the higher education in China. The purpose to conduct top-quality course selection is to help the universities to establish and form the mechanism of course construction and course operation in line with their own contexts, so as to deepen the top course program continuously. The criteria for the assessment of top-quality courses are intended to reflect scientifically the basic features of these courses and guide universities to work hard on these courses and build up initiatively top-quality courses with their own distinctive features.

With the development of molecular biology,molecular targeted therapy has become main direction and trend at the aspect of oneotherapy in the 21th century.Molecularly targeted agents which target VEGF/VEGFR,EGFR.Raf/MAPK-ERIC,HGFR,as well as associating with other therapies are available in the clinical treatment of primary hepatic carcinoma,and inspiring results have also achieved in some clinical trials.The review attempts to summarize the clinical research advancemem in molecularly targeted therapy of primary hepatic carcinoma.

Objective To observe the changes of PI3K/Akt signaling pathway and endoplasmic reticulum stress related protein GRP78 and CHOP in CCl4 induced liver fibrosis and to explore their effects on hepatic fibrosis.Methods Thirty SD rats were randomly divided into normal control group, 4 and 8 weeks liver fibrosis group (hypodermic injection of 40% CCl4).Pathological changes of liver tissue was observed by HE staining.The techniques of real-time PCR was applied to detect mRNA of GRP78 and CHOP in liver.Detected expression of Akt1, phospho-Akt1, GRP78 and CHOP protein by western blot.Meanwhile, the cell apoptosis in liver was detected by TUNEL.Results Compared with the normal control group, GRP78 and CHOP mRNA and protein in 4 and 8 weeks liver fibrosis group was increased(P<0.05), while expression of Akt1, phospho-Akt1 in 4 and 8 weeks liver fibrosis group was lower than that in normal control group(P<0.05).Compared with normal control group, the apoptosis of hepatocytes in 4 and 8 weeks liver fibrosis group was elevated (P<0.05).Conclusions PI3K/Akt signaling pathway and endoplasmic reticulum stress may play important roles in the induction of apoptosis of hepatocytes in rats with hepatic fibrosis.

Corn meal was hydrolyzed in HCI ,and pH adjusted to 6.8 with (NH_4)OH. The substrate was inoculated with Cadida trapicalis ,then cultivated in a shaker at 30℃ and in 200r/min for 2 days. The Results indicated that the protein content in corn meal grew from 8.4 to 27.4%the lysine in the protein increased from 32.1 to 73.48/kg,the tryptophan from 6.8 to to 14.8g/kg. This shows that the nutritional value of corn meal can be improved with this method.

A comparative study on the histological and morphological characteristics and the intrinsic quality of the roots of Huabei Qianhu(Peucedanum harry-smithii),Shaomao Bei Qiau hun (P.harry-smithii var.subglabrum ) and Baihua Qianhu (P.praeruptorum ) was carried out. Results revcaled that the former two Qianhu produced in Gansu are similar to Baihua Qian hu in their main ingredients.Thus the two Qianhu are worthy for further research and develo pm ent.At the same time, it was observed that Baihua Qianhu Produced in Gansu is of iuferior quality and the content of EtOH extraet of its root is slightly lower than that from elsewhere in China.

BACKGROUND:The quantity and function reduction of circulating endothelial progenitor cells(CEPCs)indicate that vascular endothelial repair capacity reduces in hypertension patients,but the impact of statins on the CEPCs is still not very clear.OBJECTIVE:To investigate the effects of atorvastatin calcium on endothelial cells and CEPCs in renovascular hypertensive rats.DESIGN,TIME AND SETTING:Randomized controlled animal experiment was performed in Chongqing Key Laboratory ofNeurology from June 2008 to Febmary 2009.MATERIALS:Totally 24 SD male rats of SPF grade,and atorvastatin calcium was produced by Lipitor,Pfizer Inc.with batch number of 65837003.METHODS:The renovascular hypertension was induced with 2-kindey and 1-clip method in 16 SD rats,which were then randomly divided into two groups:hypertensive group(n=8)and statins group(n=8).control group(n=8)underwent the same operation,without silver slip.At 4 weeks after model construction,statins group was treated with atorvastatin calcium MAIN OUTCOME MEASURES:At 4 and 12 weeks of the experiment.three groups of rats were measured blood pressure and blood lipids;at 12 weeks,the thoracic aortic endothelial cells continuity was investigated through hematoxylin-eosin stain;the quantity,proliferation,adhesion and migration capacity of CEPCs were determined.RESULTS:At 4 and 12 weeks of the experiment,there was no significant differences in the systolic pressure between statins RESULTS:At 4 and 12 weeks of the experiment,there was no significant differences in the systolic pressure between statins group group and model group,which were dramatically high than control group(P＞0.01):the blood lipids in the statins group was not changed.In the model group,rat aortic endothelial cells were greatly damaged;the injury of CEPCs was dramatically relieved in the model group.Compared with statins group and control group,the number of CEPCs was significantly decreased,the capacities of proliferation,adhesion and migration were also significantly reduced in the model group(P＜0.01);moreover,statins group was inferior to control group in terms of these capacities.with significant differences among three groups(P＜0.01).CONCLUSION:Renovascular hypertensive rats thoracic aortic endothelial calls are severely damaged,CEPCs decline in the humber and function;atorvastatin calcium can increase the number of CEPCs and improve the function of CEPCs.