2.The establishment of comprehensive evaluation index for colleges of stomatology in China
Chinese Journal of Medical Education Research 2011;10(2):160-162
Comprehensive evaluation for colleges of stomatology is a complex systematic engineering, which is affected by the determination of index and weight. Based on the previous research results,this study establishes a comprehensive evaluation index for colleges of stomatology in China by applying Delphi method,carrying out two-round consultation to 45 experts,which includes 4 first layer indicators and 21 second layer indicators.
3.Effects of Modified Yishen Zhuyang Huoxue Huazhuo Formula on Changes of Polycystic Ovarian in Patients with Polycystic Ovarian Syndrome
Chinese Journal of Information on Traditional Chinese Medicine 2015;(6):35-38
Objective To observe the effect and safety of modified Yishen Zhuyang Huoxue Huazhuo Formula for polycystic ovarian syndrome (PCOS) in the TCM pattern of deficiency of spleen and kidney with phlegm-dampness. Methods Totally 123 cases were recruited into this study and randomized to two groups by central random approach, 64 cases in the observation group and 59 cases in the control group. Patients in the observation group were given the modified Yishen Zhuyang Huoxue Huazhuo Formula, while those in the control group were given compound cyproterone acetate tablet, for two treatment courses, three months for one course. The changes of ovarian volume and the number of follicles before and after treatment were observed. Adverse reactions were also evaluated. Results Bilateral ovarian volumes in both groups decreased after treatment (P<0.05, P<0.01), while the control group showed a significant better improvement (P<0.05). The number of follicles in the two groups decreased, but no significant difference were observed between the two groups (P>0.05). The rate of adverse reaction in the observation group was lower than the control group. Conclusion Modified Yishen Zhuyang Huoxue Huazhuo Formula is effective for PCOS patient by reducing the ovarian volume with a low incidence of side effect.
4.Preoperative assessment strategies of hilar cholangiocarcinoma
International Journal of Surgery 2013;40(11):772-775
At present,in the opinions of the domestic and foreign scholars,the only hope of long-term survival even cure of hilar cholangiocarcinoma was obtained by radical resection(ie R0 resection).The application of preoperative assessment with appropriate and comprehensive strategies can judge the respectability and Intraoperative safety accurately to the tumor,thereby it can improve the radical resection rate and safety of patients with hilar cholangiocarcinoma.In this paper,preoperative assessment strategies are reviewed.
5.Research progress of epidemiology and clinical characteristics of pertussis
Chinese Journal of Applied Clinical Pediatrics 2014;29(22):1681-1682
Pertussis is an severe infectious respiratory disease that continues to be a serious public health problem,which is caused by Bordetella Pertussis.Because it's highly infectivity,it is still an important etiological factor associated with persistent cough in adults and adolescents.With the introduction of mass vaccination in 1974,there has been a dramatic decrease in the morbidity and mortality.However,in recent years,increasing numbers of pertussis are reported in adolescents and adults in many countries where with high vaccination coverage.The thesis summarize and discuss the progress of pertussis cpidemiology and clinical characteristics.
6.An optimized 3-step strategy for preventing and treating post-operation relapse and metastasis of malignant tumors with traditional Chinese medicine
Journal of Integrative Medicine 2007;5(1):5-10
Abstract: Relapse and metastasis are the main causes responsible for failure of surgical operation in treating malignant tumors. This article introduces the present development in post-operation treatment of lung cancer, liver cancer and stomach cancer, showing that the synthetic treatment by stages combined with traditional Chinese medicine is the important way to prevent and treat the post-operation relapse and metastasis of tumors, and suggesting the optimized method for treatment.
8.GENETIC DIVERSITY OF SMOOTH-SHELLED ONCOMELANIA HUPENSIS FROM MAINLAND OF CHINA BY USING RANDOM AMPLIFIED POLYMORPHIC DNA TECHNIQUE
Jing XU ; Jiang ZHENG ;
Chinese Journal of Schistosomiasis Control 1989;0(04):-
Objective To analyze the genetic diversity of snail populations from five provinces in China mainland. Methods Genomic DNA was amplified by random primer and the products were electrophoresed by 8% polyacrylamide and stained by 0.6% silver nitrogen. The results were recorded and analyzed. Results The average similarity and match percentage among the nine snail populations were 0. 721 4 and 0. 680 9 respectively. The cluster trees showed that the nine snail populations could be divided into three groups ; snails from Dali of Yunnan Province and Puge of Sichuan Province were the first isolated group; snails from Fuqing of Fujian Province and Dongtai of Jiangsu Province were clustered into the second group; the other four populations from Anhui Province and snails from Yixing of Jiangsu Province belong to the last group. Conclusion There is a large diversity among smooth-shelled snails in China although close relationship exists. The cluster trees gained by different snail populations are basically the same and consistent with the distribution of these populations. However, further study should be carried out on the cluster of smooth-shelled snails from Dongtai of Jiangsu Province.
9.Focusing on the treatment of diabetic macular edema
Chinese Journal of Ocular Fundus Diseases 2016;32(2):119-121
Diabetic macular edema (DME) is thickening retina with two disc diameter,which is the leading cause of blindness in diabetic retinopathy patients.The initial studies demonstrated that laser treatment of DME prevented further visual deterioration but did not improve visual acuity.Although glucocorticoid slow-release system can extend the time of effective drug concentration,to help glucocorticoid better carry out its biological effect,further studies are needed to warrant their safety due to increasing intraocular pressure and cataract progression.Novel studies identifying the presence of vascular endothelial growth factor (VEGF) in the eye with DME allowed for the development of an alternative anti-VEGF therapy,which revolutionized the management of DME by not only preventing vision loss,but also improving overall vision.Anti-VEGF therapy is becoming the first-line treatment of DME.However,present treatment modalities including anti-VEGF for DME had limitations,which build on the current understanding of DME pathogenesis.Further in-depth study of the development and outcome of DME is needed to optimize the therapeutic schemes,based on objective and scientific observation of treatment response.Finally we need to fully utilize the public health services and clinical management resources for diabetic patients,to prevent the visual impairment of DME before its occurrence.
10.Application of Genetic Testing in Individualized Antiplatelet Therapy for Acute Coronary Syndrome Pa-tients after Percutaneous Coronary Intervention
China Pharmacy 2017;28(23):3285-3289
OBJECTIVE:To investigate the value of genetic testing in clopidogrel individualized antiplatelet therapy for acute coronary syndrome(ACS)patients after percutaneous coronary intervention(PCI). METHODS:Clinical pharmacists participated in therapy for 3 ACS patients after PCI,and analyzed risk factors of stent thrombosis as the degree of lesion complexity,length and number of stents,complication,smoking history,etc. Clinical pharmacists suggested conducting clopidogrel genetic testing (CYP2C19,PON1,ACBC1),and suggested replacing antiplatelet agents,maintaining original plan and strengthening monitoring according to the results of genetic testing. RESULTS:The physicians adopted the suggestions of clinical pharmacists. After optimiz-ing antiplatelet therapy according to the results of genetic testing and clinical factors,3 patients were stable and discharged from hospital with drugs. CONCLUSIONS:Genetic testing can provide evidence for the formulation of individualized antiplatelet thera-py in ACS patients after PCI,and can be regarded as one of the breakthrough points for clinical pharmacists to carry out pharmaceu-tical care. In conducting genetic testing,clinical pharmacists should evaluate the risk of thrombosis in ACS patients and select the appropriate population for testing. At the same time,the clinical factors as medication compliance,stent thrombosis risk,therapeu-tic efficacy,ADR,and evidence-based pharmaceutical evidence should be comprehensively evaluated on the basis of genetic test-ing,and antiplatelet therapy plan should be optimized so as to guarantee the safety and effectiveness of drug use.