1.Application of health coaching in chronic non-communicable disease management
Chinese Journal of Health Management 2016;10(6):475-478
There are some common problems such as recurrent symptoms and poor compliance among patients with chronic diseases. Although scientific knowledge and skills have been learned from traditional health education, patients with chronic diseases cannot improve their life style continuously. At present, many researches abroad have proved that health coaching contributes to setting feasible goals and encourages continuously behavior change of patients. In China, health coaching is in the stage of becoming familiar with its scientific definition, intervention effect and application characteristics. And health coaching also needs evidences from high-level evidence-based studies. Along with continuous improvement of intervention techniques on health management, health coaching will get further development and standardization.
2.Triangle relationship of PTH, intracellular calcium and CaSR in myocardial damage
Chinese Journal of Pathophysiology 2017;33(1):179-183
Parathyroid hormone ( PTH) is an important hormone secreted by parathyroid cells , and regulates the metabolism of calcium and phosphorus in the body .In recent years , the toxic effect of PTH on myocardium has been re-ported.Calcium-sensing receptor (CaSR), a member of G protein-coupled receptor family, can feel the subtle change of extracellular calcium concentration and regulate intracellular calcium concentration through multifarious ways in order to control the secretion of PTH .The expression of CaSR is observed in parathyroid cells , renal tubular epithelial cells , myo-cardial cells, etc.Intracellular calcium, as a second messenger, participates in various cell functions , such as excitation-contraction coupling , fertilization and so on .The injury of myocardial cells is intimately linked with high concentrations of PTH and intracellular calcium , and high expression of CaSR .
3.Progress in diagnosis and treatment of bronchiolitis
Chinese Journal of Applied Clinical Pediatrics 2017;32(4):253-255
Bronchiolitis is the most common lower respiratory tract disease in infants younger than 2 years of age.Many viruses can cause bronchiolitis,however,respiratory syncytial virus is most common etiology.The pathological characters are acute inflammation,edema,necrosis of epithelial cells and mucus productions increased.Diaguosis of bronchiolitis is based on clinical signs and symptoms and a thorough history and physical exam.The disease severity and risk factors for severe disease need to be assessed.The treatment of bronchiolitis has been largely supportive.Continuous positive airway pressure treatment has been accepted for severe cases.Palivizumab prophylaxis is probable in high risk infants.Hand hygiene,decreasing tobacco smoke and breastfeeding are considered as efficient preventive methods.
4.Effects and mechanisms of exogenous nesfatin-1 injection in the central nucleus of the amygdale on exploratory behavior in rats
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(12):1066-1069
Objective To explore the effects and mechanisms of nesfatin-1 injection in the central nucleus of the amygdale(CeA) on exploratory behavior in rats.Methods Fifty rats were divided into 5 groups randomly : nesfatin-1 low dose group, nesfatin-1 high dose group, SHU9119 group, SHU9119+nesfatin-1 low dose group and control group.Drugs were administrated via CeA to examine behavioral changes of rats by elevated plus maze model test and nesfatin-1 mRNA expression in CeA of anxiety rats (10 rats).Results Compared with the control group,anxiety behaviors of rats in nesfatin-1 low dose group and nesfatin-1 high dose group were improved remarkably,showing that the open arm entries were significantly reduced (OE, t=4.16-12.87, P<0.01), open arm entry proportion was decreased remarkably (OE%, t=2.39-4.39, P<0.01-0.05), and time proportion in open arm was decreased significantly (OT%, t=5.43-20.55, P<0.01),which presented dose dependent.Compared with the control group, anxiety degree of rats in nesfatin-1 low dose group and nesfatin-1 high dose group significantly enhanced, showing that the rats head dipping reduced obviously (HD, t=6.97-16.73, P<0.01) ,while rearing was increased significantly (RE, t=6.60-13.25, P<0.01) ,which was presented dose dependent.Melanocortin receptor antagonist SHU9119 can partly eliminate nesfatin-1 induce-anxiety (t =2.11-3.08, P< 0.01-0.05).Real-time PCR results showed that nesfatin-1 mRNA expression of anxiety model rats was significantly increased (t =3.40-5.58, P<0.05).Conclusion Amygdala nesfatin-1 can increase anxiety and fear of rats,which may be associated with melanocortin systems.
5.Protection of intellectual property rights for traditional village culture and its model
Chinese Journal of Medical Library and Information Science 2015;(5):13-17
The protection model of intellectual property rights for traditional village culture were studied by investi-gating its current situation , related problems and why they exist in Yongzhou City , Hunan Province , China .
6.Evaluating the Compensation Level of Urban Basic Medical Insurance in Jiangsu
Chinese Health Economics 2013;(12):30-32
Objective: To evaluate the compensation level of the Urban Employee Basic Medical Insurance ( UEBMI ) and Urban Resident Basic Medical Insurance ( URBMI ) in Jiangsu province . Methods: Take catastrophic health expense as the bottom line of compensation ratio for the basic medical insurance, the benefit of hospitalization expenses of those joining the insurance as the actual line of compensation ratio, and quartile division was used to comparatively analyze the differences between the bottom line of compensation ratio and the actual line of compensation ratio. Results: Take 10%as the critical value of catastrophic health expense, the actual line of compensation level is higher than the bottom line of compensation level in UEBMI, and there is reverse in URBMI. Conclusion: In some extent, the compensation level of UEBMI has relieved the economic burden of the poor jointed group because of sickness, while limited compensation level of UEBMI is in need of further improvement.
7.Determination of Baicalin in Scutellaria baicalensis Georgi. in the Different Parts by HPLC
Journal of China Pharmaceutical University 2001;(3):235-236
AIM The content of baicalin in Scutellalria baicalensis Georgi. in the different parts was determined by RP-HPLC. METHODS The mobile phase was a mixed liquid with MeOH-Water-H3PO4(60∶40∶0.2). Standard curve showed a linearity within the range of 0.36~0.84 μg/ml(r=0.9995), the average recovery was 99.28%, and RSD=1.4%(n=5). RESULTS The results showed that the content of baicalin is highest in the bark (cortex) part of Scutellalria baicalensis Georgi.
8.Variability and clinical application of metabolic markers of bone
Tianjin Medical Journal 2015;(2):221-224
Metabolic markers were released in the process of bone resorption and formation during bone remodelling. These markers have been extensively studied in trials of osteoporosis and other metabolic bone disorders during the past de?cades. Bone metabolic markers can replenish bone mineral density in the management of osteoporosis, but their use in clini?cal practice is challenged by their variability. Recently, there are many great progress in research of bone metabolic markers application in non metabolic bone disorders.
9.Significance and methods of compiling Synopsis for the general list of medical documents in minority nationalities
Chinese Journal of Medical Library and Information Science 2014;(1):52-55
Proposed in this paper is to compile The synopsis for the general list of medical documents in minority nationalitiesand to make the scientific classification and systematic organization of medical documents in minority nationalities, thus breaking their time and space limitation and laying the foundation for the establishment of medi-cal literature resources support system, according to their scattered collection, severe damage, abstruse written lan-guages, and the fact that most of them are unorganized or catalogued, which significantly hinder their development and utilization.
10.The effects of Ghrelin on food choice of rats
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(1):4-7
Objective To study the effect of Ghrelin on food choice of rats.Methods Twenty-four Wistar rats were randomly divided into control group,0.1 nM Ghrenlin group and 1.0 nM Ghrenlin group,and 8 rats in each group.0.2 μl arificial cerebrospinal fluid were injected into the lateral ventricle in control group,and the same volume 0.1nM and 1.0 nM Ghrelin were done in 0.1 nM Ghrenlin group and 1.0 nM Ghrenlin group respectively.The changes of food intake,feeding interval,and torlerance of different flavors of food intake were observed.The SCH23390,an antagonist of dopamine D1 receptor,was used to explore the mechanisms of Ghrelin.Results The rats' food consumption increased significantly and the intake intervals reduced dose dependently after injecting Ghrelin into the lateral ventricles (P<0.05 ~ 0.01).Compared with normal liquid food,the rats' intake of food added with quinine was reduced((16.73±5.21)ml vs (23.47±9.46)ml,P<0.01),and injecting Ghrelin into the lateral ventricles could not reverse this effect ((13.74±3.29) ml vs (16.73±5.21)ml,P>0.05).Mter injecting Ghrelin,the rats' intake of liquid food added with sugar increased in a dose dependent manner(P<0.05 ~ 0.01),and higher than the food intake of fasted rats ((59.24 ± 17.32) ml vs (38.13 ± 10.98) ml,P< 0.05).The food intake reduced obviously after injecting SCH23390 ((22.69±6.54) ml vs (28.21±7.35)ml,P<0.05).But the rats' food intake was significantly lower after injecting SCH23390 ± Ghrehn than the rats only injected of Ghrehn ((3Z44±10.62)ml vs (65.81±13.47)ml,P<0.05).Conclusion Ghrelin can affect the food choice of rats,and dopamine may be involved in the regulation of this process.