The article reviewed the concept of normal binocular vision and general examination methods of binocular vision and its normal range.New investigation progresses about monocular and binocular depth perception in neuro-physiology and neuro-anatomy were introduced.The depth perception from monocular and binocular depth cues was integrated in parietal area of caudal intraparietal sulcus(CIP).Mono-eye also had depth perception.Strabismus and amblyopia could damage the binocular vision and binocular depth perception.Binocular vision damage and its treatment results with doffing suppression training,fusion training,and stereopsis training in strabismus and amblyopia patients were explained in detail in this article.

[Objective] To discuss the operation mode of thyroid tiny papil ary caracinoma and offer foundation for clinical choice. [Method] Make analysis on the clinical data and fol ow-up results of 176 cases of the disease above. [Result] Al were made operation, and there ’re no death. Compare the resec-tion of deseased gland and isthmus with ful resection of the thyroid, the difference of hoarse sound and low-calcium occurrence rate had statistical mean-ing; on uni-lateral and double lateral central ALND, the hoarse sound and low-calcium occurrence rate had no marked statistical meaning. [Conclusion] The diseased gland and isthmus resection+double lateral ALND not only doesnt ’increase post-operation complications, but improves patients ’life quality, which is the main operation for thyroid tiny papil ary carcinoma.

The differentiation of cells types and layers in the cerebellar cortex of 74 white micefrom the time of birth to the adult age were observed by the methods of Nissl, Golgi,Cajal and Golgi-Cox. The external granular layer of the folia of the cerebellar cortex attained the greatestthickness in the fourth on the fifth day; at the same time, mitosis was seen. There after,this layer became gradually thinner; from eighteenth to twentieth day after birth it even-tually disappeared. Some cells of the external granular layer differentiated into granular and stellatecells. The Purkinje cells after birth were in primitive form with perisomatic dendrites.From the eighth day on, perisomatic dendrites became atrophic and disappeared. In thethird week, the Purkinje cells reached the mature stage. The Purkinje cells after birth, besides the ones in their normal position, might befound in the submeningeal spaces, external granular layer, molecular layer, internal granu-lar layer and medulla of the cerebellum. A part of these displaced cells may be origi-nated from the external granular layer. With the disapperance of the external granular layer, the Purkinje cells becamecompletely matured. In accordance the animals in this period began to be able of in-dependent activities, such as running, jumping, etc.

Objective To observe and analyze the euthyrox intervention effect of early hypothyroidism after 131I therapy for hyperthyroidism. Methods 200 cases of patients with hyperthyroidism in our hospital from March 2014 to April 2016 were selected as the object of the experiment needs, all the patients were randomly divided into two groups, respectively into study group and control group, two groups there are 100 patients. All patients before admission were accepted 131I treatment, control group received routine treatment, the study group was treated with 131I in twentieth days after start of continuous use of euthyrox, 20 days of continuous use, the two groups of patients with thyroid ultrasound, thyroid gland imaging, thyroid function and perturbation the rate of iodine was detected and observed. And the two groups of patients in the clinical efficacy of different after treatment were compared. Results The patients in the study group and the control group in 3 months after treatment, 9 months and 12 months the incidence of hypothyroidism were compared, research The incidence rate of hypothyroidism group was significantly lower than the control group, the differences between the groups were statistically significant (P<0.05). Patients in the study group and the control group at the same time, the cure rate of hyperthyroidism compared to the study group was significantly higher than that of control group, with statistical significance (P<0.05). Conclusion In patients with early after 131I treatment for patients taking euthyrox can to some extent reduce the occurrence of hypothyroidism, but also can improve the cure rate of hyperthyroidism for the first time, a higher application value.

Bombesin in central nervous system (CNS) is closely related to thermoregulation. Injection of bombesin into some parts of brain caused hypothermia significantly, especially in POAH, and this effect can be enhanced by the cold ambient temperature. The mechanism might be suppress heat production and disrupt the regulatory function of thermoregulatory centre. Morever, other neuropeptides, food deprivation and lesion of VMH (ventromedial hypothalamus) affected the action of bombesin.

Drug Therapy, Combination ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Medicine, Chinese Traditional ; Phytotherapy

The tumor patients always suffer from the serious metabolic disorder,and nutritional support for patient may improve the nutrition condition and meanwhile promote tumor growth.Application of amino acid imbalance solution,which may lead to the overdose or deficiency of some specific amino acid:arginine,leucine,methionine,valine,tyrosine,phenylalanine can contribute to improvement of patientk's nutritional condition and inhibition of tumor growth.

Objective To study the genetic polymorphisms of STR locus D20S85 and to obtain the genetic data of Guangdong Han, Guangxi Zhuang, Huadong Han,Neimenggu Han and Meng populations. Method Using PCR and silver - staining methods, the alleles of D20S85 locus were detected and analysed. Results 9 alleles and 35 genotypes were found in those populations. The highest allele frequency was D20S85* 6. The results of Hardy - Wein-berg equilibrium test showed that the genotype distributions observed in five populations were correspondent with the expected. The expected heterozygosity was 0.7720 - 0.7912; the exclusion probability of paternity was 0.7538-0.7594(triplet) and 0.3988 -0.4297 (biplet) ; the discrimination power 0.9175 -0.9272 and the polymorphism information content 0.7442 - 0.7656. Conclusion STR D20S85 locus is a useful genetic marker for forensic application .

Objective To prepare optimization of notoginsenoside R1 chitosan nanoparticles,to provide a theoretical basis for clinical application of the drug.Methods Notoginsenoside R1 chitosan nanoparticles were prepared,HPLC method was used to detect the content of notoginsenoside R1 chitosan nanoparticles,preparation technology of nanoparticles were optimized by orthogonal experiment,and the optimized preparation technology of nanoparticles was verified.Results HPLC standard curve equation was A =911.49C -1803.4(r =0.999 9),linear range was from 25 to 900 g/mL.The intra day precision were 1.520%,0.884% and 0.969%(n =6),and the inter day precision were 1.591%,1.447% and 1.269%(n =6).The recovery rates of low,medium and high concentra-tions were (98.11 ±1.16)%,(101.27 ±0.59)% and (100.97 ±0.82)%.4 factors of orthogonal experiment:the concentration of chitosan,the mass ratio of drug and carrier,temperature and rotational speed,and 3 levels of each factor were selected.The average particle size,encapsulation efficiency and drug loading were selected as control indexes.The test results were determined by the method of comprehensive weighted scoring.The orthogonal design was designed according to L9(34)orthogonal design.The optimization process was 2% of chitosan concentration,20% of the weight ratio of drug and carrier,35 ℃ of temperature,600 r/min of rotational speed.According to the optimized process,the average particle size was (123.40 ±7.68)nm,the encapsulation efficiency was (58.41 ±1.59)%,and the drug loading amount was (10.46 ±0.53)%.Conclusion The optimized preparation process of notoginsenoside R1 chitosan nanoparticles is simple and easy to operate,the entrapment efficiency and drug loading amount were high. As a new dosage form,it has a good clinical application prospect.

0bjective To compare the curative effects of GnRH-a and mifepristone in treatment of endometriosis after laparoscopic operation.Methods 114 cases of patients were selected from March 2012 to December 2014 in our hospital with endometriosis after laparoscopic surgery,randomly divided into mifepristone group,GnRH-a group and untreated group,each group for 38 cases.mifepristone group were treated by oral mifepristone one week after operation,25 mg,qd,continuing to take 6 months;GnRH-a group,post operative 1 week received injection of GnRH-a (Tamiflu)3.75 mg,once every 4 weeks,6 times in a row;The untreated group,fails to drug treatment.To compare the symptoms,relapse rate pregnancy rate and serum hormones including FSH, LH and E2 levels.Results After treatment, the total effective rate of GnRH-a and mifepristone group is significantly higher than the untreated group(P<0.05),and the recurrence rate is lower than the untreated group(P <0.05),the pregnancy rate is higher than the untreated groups(P<0.05).The recurrence rate,the remission rate and the pregnancy rate of mifepristone group are lower than the untreated group,there was no statistical significance.Conclusion Mifepristone and GnRH-a can both,effectively reduce the recurrence rate after EMT laparoscopic surgery,can guarantee the pregnancy rate,reduce the adverse reaction.