A study on 115 patients with breast cancer treated by postoperative radiation and vitexin within 6 months has shown that there were changes of serum concentration of products of lipid peroxydation in patients with breast cancer in the different duration of treatment. An increase of serum MDA after radiation showed an increase of oxidation stress. Vitexin helped the establishment of oxidation balance only after a month of the treatment. The cell-mediated reduction of immunoresponse was a outcome of oxidation stress. The recovery of response of lymphocyte transform in the peripheral blood was corresponding to the improvement of oxidation balance by drug.
Breast Neoplasms ; Serum ; therapeutics ; Lymphocyte Activation ; Radiation ; vitexin ; Antioxidants