Sustained release film coated tablets containing dexchlorpheniramine maleate were prepared in such a structure as two-third of drug were dispersed in Eudragit RS 100 to form insoluble matrix that gradually releases drug by diffusional mechanism, the rest was dispersed in the immediate release part. The core tablets were compressed by a wet granulation process and the film coated tablets by a routine film coating process with Eudragit E suspension. The formed coated tablets have suitable technical characteristics. The third formulation with Eudragit RS- drug ratio 2:1 has got the dissolution extent and the release rate in vitro similar to those of Polaramine 6mg repetabs. They also meet the requirements invitro release rate versus time for sustained release capsules containing Chlorpheniramine maleate by USP XXIII. Therefore, these film coated tablets with dexchlorpheniramine maleate may be candidates for a sustained release dosage form
dexchlorpheniramine ; Tablets

Quantitation of Metronidazole by reversed phase liquid chromatography using Supelco LC-ABZ column and a mobile phase containing an acid aqueous phase (pH Metronidazole ; Tablets

Study on some methods used to quantify berberine chloride showed that the UV measuring and volumetric titration methods did not express only amount of berberine chloride itself. It is necessary to apply high- performance liquid chromatography (HPLC) to achieve the optimal conditions for better splitting, higher accuracy…in order to apply more widely in testing products commonly in market with many components combined to berberine chloride. To find out optimal methods, which are suitable with condition of present some pharmaceutical units, it is necessary to experiment continuously methods such as UV measuring and volumetric titration,… using HPLC method to compare.
Berberine ; Tablets

A microbiological extract of pollen, Cernilton was administered orally in dose of four tablets daily for 14 to 36 days in 25 cases of chronic prostatitis and following results were obtained. 1) Of the cases, 13 cases' (72%) Were improved and 7 cases(28%) were. not improved.. 2) No deleterious side effect were observed.
Pollen ; Prostatitis* ; Tablets

A microbiological extract of pollen, Cernilton was administered orally in dose of four tablets daily for 14 to 36 days in 25 cases of chronic prostatitis and following results were obtained. 1) Of the cases, 13 cases' (72%) Were improved and 7 cases(28%) were. not improved.. 2) No deleterious side effect were observed.
Pollen ; Prostatitis* ; Tablets

Chronic prostatitis has various symptoms and many problems in management. Recently a lipidosterolic extract of Serenoa Repens, Permixon has been reported to reveal potential antiandrogenic and anti inflammatory activities on prostate. Then we used Permixon on chronic prostatitis and following results were obtained. Permixon is administered orally in dose of 160mg., b.i.d. for 60 days in 31 cases of chronic prostatitis in 1st group, Permixon 160mg, with Cipro-floxacin 500mg, b.i.d. in 35 cases in 2nd group and Placebo 2 tablets, b.i.d. in 30 cases in 3rd group. In 1st group 36 cases(77.4%) were improved, 29 cases(82.8%) in 2nd group and 7 cases (23.3 %) of 3rd group were improved. Permixon is an effective drug in chronic prostatitis and there was no changes in laboratory findings and negligible side effects were noticed
Prostate ; Prostatitis* ; Serenoa* ; Tablets

to build formula of captopril sustained release matrix tablets with EC and HPMC, survey the affects of formulation components and optimization of formula by using D- Optimal. Subject: captopril, EC, HPMC, lactose, and starch. Method: prepare tablet, assess the quality of captopril sustained release matrix tablets. Conclusions: From the experiment design, captopril sustained release oral tablets with half life of 12h can be prepared, and by optimized method, the proper formula was found. To produce captopril tablets, it's necessary to further study in large scale, to perform test of bio-equivalence and stability of tablet
Captopril ; Tablets ; Pharmaceutical Preparations

The effect of Ha Noi College of Pharmacy producted CTK tablet containing 0.5g CTK mixed powder on bacterial utero-vaginitis was studied on 31 female married subjects aged 18-44. Chloramphenicol 0.25g tablet producted by Central pharmaceutical Factory N2 was used control. Results showed that CTK tablet manifests antibacterial effect compared with chloramphenicol in utero-vaginitis. Antibacterial effect is 65.4% by a dose of treatment (20 times of application of tablet). The effect of healing the lesion was manifested earlier than that of chateravaginitisull
Tablets ; Vaginitis ; Bacterial Infections

Using the full quadratic model in drug dissolution optimization, the authors built up the sustained release of diclofenac tablet formulation with hydrophilic matrix excipient. The sustained excipient releases xanthan gum which has good features such as controlling medical substance regularly, rubbing seed easily, covering tablet easily and compressed force with a little affect to the rate of medical substance release. This formulation can be applied in making up medicines with a wider scale. It is being tested its stability and evaluated its availability to apply in manufacture
Diclofenac, Pharmaceutical Preparations , Tablets

The capacity of dissolution of active component of the tablet of ciproflaxacin. 6 samples composing of 78 domestic and foreign ciprofloxacin tablet were tested. Results showed that 2 of 3 samples of domestic tablet did not meet the requirement for dissolution mentioned to USP XXIII, while the foreign tablets manifested a rate of dissolution higher than that of pharmacopea
Ciprofloxacin ; Pharmaceutical Preparations ; Tablets