Objective To investigate the clinical effects of the traditional rehydration and sub-shock therapy for pre-hospital treatment of traumatic shock.Methods Two hundred and sixteen patients with traumatic shock,were divided into two groups by random digits table:group A (103 cases) and group B (113cases).Group A was treated by traditional rehydration method,group B was treated by sub-shock therapy.The mortality,incidence of serious complications,and laboratory parameters between two groups were compared.Results The total mortality in group A was significantly higher than that in group B [38.8％ (40/103) vs.25.7％ (29/113),P ＜ 0.01].There was no statistically significant difference in ＜ 1 h,＞ 2 h mortality between two groups (P＞ 0.05).The 1-2 h mortality in group A was significantly higher than that in group B [18.4％(19/103) vs.8.0％(9/113),P ＜ 0.05].The incidence of serious complications in group A was significantly higher than that in group B [41.7％ (43/103) vs.21.2％ (24/113),P ＜ 0.01].Treatment of 1 h various laboratory parameters in group B were significantly better than those in group A (P ＜ 0.01 or ＜0.05).The average amount of fluid in group A was significantly more than that in group B [(2352.6 ± 763.1)ml vs.(592.4 ±236.3) ml,P ＜0.01].There was no statistically significant difference in systolic blood pressure between two groups (P ＞ 0.05).Conclusions Sub-shock therapy in pre-hospital emergency treatment of traumatic shock has some advantages compared with traditional rehydration method,which is conductive to the maintenance of the patient' s vital signs,to reduce bleeding and improve patient treatment rate.

Objective To investigate the correlations between plasma levels of interleukin(IL)-17,-10,-4 and interferon(IFN)-? and their clinical implications in children with asthma.Methods Twenty-two children with asthma and twenty healthy children were enrolled in the study.Blood samples from these patients were collected at acute and convalescent stages.The plasma levels of IL-17,-10,-4 and IFN-? were detected by ELISA method.Results The plasma level of IL-17 was significantly decreased in children with asthma at the acute and convalescent stage compared with healthy controls(P

Cardiovascular Diseases ; drug therapy ; prevention & control ; Humans ; Hypolipidemic Agents ; administration & dosage ; therapeutic use ; Risk Reduction Behavior

Colitis, Ulcerative ; therapy ; Humans ; Integrative Medicine ; Medicine, Chinese Traditional

Coronary Disease ; drug therapy ; Humans ; Hypolipidemic Agents ; administration & dosage ; therapeutic use

Objective To investigate the mechanism of renal interstitial fibrosis after unilateral ureteral obstruction and renal protctive effect of angiotensin coverting enzyme inhibitor (ACEI),benazepril on rat kidney.Methods Twenty-four rats were randomly assigned to shame operation group (normal group),operation group, benazepril(10mg?kg -1 ?d -1 ) treatment group after unilateral ureteral obstruction. Renal tissues were examined by light and electronmicroscopy at the 2nd week after operation. Immunohistochemistry was applied to measure the expression of collagen Ⅲ,transforming growth factor ? 1 (TGF-? 1 ) and nuclear factor-kB(NF-kB) in the renal interstitium.Results In comparison with shame operation group, the expression of collagen Ⅲ , TGF-? 1 and NF-kB in the interstitium of operation group markedly increased (P

Objective To analyze the expression of cholecystokinin(CCK) in rat' s hippocampus and cerebral cortex following heat stress and febrile convulsions (FC). Methods Warm water was used to induce FC model. Immunohistochemistry method tested CCK protein. Results Very few or no CCK neurons were seen in the control rats. There was weaker expression of CCK in cerebral cortex of HS group,mainly located in PIR,ENT and RS subfield.No CCK positive ceiis were seen in hippocampus of HS rats. In contrast, abundant expression of CCK protein was found in hippocampus and cerebral cortex of FC group. They were well-distributed, without characteristic subnucleus-specific distribution. Conclusion Abundant induction of CCK in hippocampus and cerebral cortex of FC group suggested that CCK may play a role in the central control of FC.

We have obtain a steady and reliable dyeing methods for the uniuncleate and dicaryotic hyphae of Pleurotus tuber-regium by using different foster hyphae way, comparing two kinds of fastness liquid and three dye stuff on the hyphae nuclear stain effect, and then optimization grouping.

Colitis, Ulcerative ; therapy ; Humans ; Integrative Medicine

Administration, Oral ; Animals ; Mice ; Nanoparticles ; toxicity ; Particle Size ; Titanium ; toxicity ; Toxicity Tests, Acute