This text the showbiz art living character to expand to the medical science of help the function to carry on thorough analysis,thus further push forward the medical science living education for all-round development of smooth open an exhibition,exaltation medical science living of thought morals character,cultural character,mental state character with appreciate beauty ability,innovation ability,competence in interpersonal communication,for set up socialism harmony society development qualified medical science talented person.

Our experiments have shown that bee venom possesses effects of significantly increasing the fluidity of erythrocyte membrane,markedly decreasing the whole blood and plasma viscosities,accelerating erythrocyte microelectrophoresis speed and reducing erythrocyte rigidity index in rabbit. The results showed that bee venom can markedly change some of the parameters of hemorrheology,and possess certain effects in promoting blood circulation to remove blood stasis.

Objective To explore the conventional MRI,diffusion-weighted imaging (DWI)characteristics and the pathological basis of angiomatous meningioma.Methods The conventional MRI,DWI and pathological manifestations of 7 cases with angioma-tous meningioma confirmed by surgery and pathology were analyzed retrospectively.The apparent diffusion coefficient (ADC)value of the tumors and contralateral normal brain parenchyma were measured and compared with each other.Results Among the 7 ca-ses,5 cases were in the convexity of brain (4 cases in the frontal part and 1 case in the parietal part),and 2 cases in the parasella. 6 cases showed hypointense on T1 WI and hyperintense on T2 WI,and 1 case showed isointense on both T1 WI and T2 WI.The necro-sis within the tumor was seen in 2 cases.The flowing void phenomenon was seen in 6 cases.The significant peritumoral edema was seen in 5 cases on FLAIR.Significant enhancement on contrast-enhanced T1 WI was seen in all the cases.The average ADC value of the tumors (1.35×10 -3 mm2/s)was significently higher than that of the contralateral normal parenchyma (0.92 × 10 -3 mm2/s) (t=7.21,P <0.01).Mature vessel component was seen on pathological section in all the cases.For immunohistochemically analy-sis,the expression of vimentin (Vim)was positive in 6 cases and scattered positive in 1 case.The expression of epithelial membrane antigen (EMA)was positive in all the cases.Conclusion The MRI features of angiomatous meningioma are closely correlated with rich blood vessels.The ADC value of the tumor is higher than that of the contralateral parenchyma,which is helpful for the diagno-sis.

BACKGROUND:Animal models can be used to study specific scientific problems of intervertebral disc biology.Model of disc degeneration is mainly used to resolve the relevant disease mechanisms and scientific and security issues of the treatment.OBJECTIVE:To summarize currently used experimental animal models of intervertebral disc degeneration study,and to dynamically observe and confirm the pathological process of disc degeneration based on disc imaging,morphology,biomechanics and bi(o)chemicel changes.METHODS:Using "intervertebral disc degeneration,animal models,in vivo,in vitro" in English as the search words,Cochrane Library (No.1 2009),Cochrane Library Database of Controlled Clinical Trials (No.1 2009),MEDLINE from 1990 to March 2009,EMbase from 1990 to March 2009,Current Controlled Trials,and the National Research Register were retrieved.Literature was limited to English language.The disc imaging,morphology,biomechanical end biochemical composition and other indicators,as well as the pathological process of disc degeneration served as the evaluation indices.The articles related to the intervertebral disc cell culture models,the whole disc tissue culture model,mechanical model,injury model,biological model,genetically modified models,spontaneous models were included.The repetitive researches and those unrelated to animal models of intervertebral disc degeneration were excluded.RESULTS AND CONCLUSION:The establishment of a reliable animal model can provide favorable conditions for studying the pathogenesis of intervertebral disc degeneration,at the same time,provides a good experimental vehicle for various researches about the repair treatment of intervertebral disc degeneration.Animal models of intervertebral disc degeneration can be divided into two categories:in vitro models and in vivo models of disc degeneration and repair.The former can be assigned into disc cell culture models and whole disc tissue culture model;the latter is assigned into mechanical models,injury models,biological models,genetically modified models,spontaneous models and so on.The above models are commonly used in the study of the occurring mechanism of disc degeneration,as well as the feasibility and effectiveness of a variety of treatments.However,there is still no generally accepted animal models as an ideal disc degeneration model,various types of models reported have their own advantages and disadvantages.

BACKGROUND:Spinal canal decompression and fusion combined with pedicle screw fixation has become the main method for the treatment of thoracolumbar fracture and dislocation. OBJECTIVE:To restore the vertebral height of the patients with thoracolumbar fracture and dislocation who underwent subtotal resection and decompression through titanium cage packed with autologous cancel ous bone and pedicle screw fixation. METHODS:Thirty-one patients with thoracolumbar fracture and dislocation treated in the Shanghai 6th People’ s Hospital of Shanghai Jiao Tong University from February 2007 to September 2011 were selected. Al the patients received subtotal resection, spinal canal decompression and titanium cage packed with autologous cancel ous bone and pedicle screw fixation. Imaging examination was performed before and after treatment to observe the recovery of vertebral sequence, vertebral height and Cobb angle, as wel as the recovery of nerve function. RESUTLS AND CONCLUSION:The patients were fol owed-up for 12 months, and al the patients healed wel after treated with titanium cage packed with autologous cancel ous bone and pedicle screw fixation, and there was no loosening, shedding or breakage after pedicle screw fixation. During reexamination, the grafts fusion, good deformity correction, basic recovery of vertebral height and good recovery of Cobb angle were observed. Seven cases had neurological function recovery, and among them, six cases raised for one degree, one case raised for two degrees, and another 22 cases without recovery. Case analysis and relative researches showed that subtotal resection and decompression and titanium cage packed with autologous cancel ous bone and pedicle screw fixation can reduce the loss of correction of the patients with thoracolumbar fracture and dislocation, restore the vertebral height, and enhance the stability of the vertebral body.

Objective To investigate the clinicopathologic and immunohistochemical features of gastric stromal tumors.Methods A total of 105 cases with gastric stromal tumors were included in the study.The expression of cluster of differentiation 117 (CD117),cluster of differ entiation 34 (CD34),smooth muscle actin (SMA),S-100 protein and Ki-67 in gastric stromal tumors specimens was detected by immunohistochemistry.The clinico-pathologic features of gastric stromal tumors were also analyzed.Results Of 105 gastric stromal tumors specimens,90 were positive for CD117 [85.7 ％ (90/105)],98 positive for CD34 [93.3 ％ (98/105)],21 positive for SMA [20.4 ％ (21/105)],60 positive for Ki-67 [56.1％ (60/105)],13 positive for S-100 [12.4 ％ (13/105)].Conclusion Combined detection of CD117 and CD34 can improve the diagnostic accuracy of gastric stromal tumors.The expression of Ki-67 can be used as a prognostic parameter for gastric stromal tumors as it is correlated with tumor size,risk and mitotic.

Partial hepatectomy (PH) is an effective method for the treatment of various liver tumors,and liver regeneration dysfunction is one of the most serious complications.Therefore,liver regeneration (LR) after PH is particularly important.In this paper,we reviewed the molecular mechanisms of LR including cellular factors,growth factors,metabolism and related signaling pathways,and reviewed the research progresses of the traditional Chinese medicine (TCM) in promoting liver regeneration.The aim was to further clarify the mechanism of the occurrence and development of LR,and to provide valuable information for the development of drugs for treating liver regeneration disorders.

Objective To observe the mechanism of the change in runx3 in gastric carcinoma its difference and with p53 mutation.Methods A total of 30 cases of gastric carcinoma were taken from clinical operation.PCR-SSCP method was used to detect mutations in exons 2,3,4 of runx3 gene in the gastric carcinoma.The methylation status of runx3 gene was examined by methylation-specific polymerase chain reaction(MS-PCR),PCR-SSCP method was used to detect mutations in exons 5,6,7,8 of p53 gene in the gastric carcinoma.Results Two cases with mutation were found,methylation of runx3 promoter region was confirmed in 87%(26/30) specimens of gastric carcinoma,53.3%(16/30)cases were confirmed with mutation in the p53 gene.The rate of methylation of runx3 was higher than the rate of mutation of p53(P

After a description of ISO11620:2014 , the international criteria for library performance assessment , how to enforce the construction of military academic libraries was systematically elaborated in terms of improving the quality and use of their resources and infrastructures, and reducing their construction cost.

Objective To discuss effective methods for treating hypertensive intracerebral hemorrhage at the different sites. Methods Different operative methods were adopted in 85 cases of hypertensive intracerebral hemorrhage at the different sites from January 2001 to August 2003 in this hospital. Small fenestration and hematoma clearance under local intensify anesthesia was conducted in 40 cases of hemorrhage under the cortex or in the lateral area of the basal ganglia and without brain hernia; small incision trepanation with suction and drainage of hemorrhage under local intensify anesthesia was used in 26 cases of hemorrhage in the medial area of the basal ganglia without brain hernia; craniotomy and hematoma clearance under general anesthesia was adopted in 11 cases of preoperative brain hernia and 6 cases of cerebellar hemispheric hemorrhage; lateral ventricle external drainage was adopted in 2 cases of brain stem hemorrhage involving into the fourth ventricle and also in these cases with ventricle involved. Results The overall mortality rate was 12 9% (11/85). There were no deaths in cases of hemorrhage without brain hernia,under the cortex, in the cerebellum, in the brain stem or in the lateral area of the basal ganglia.The mortality was 29 0% (9/31) in cases of hemorrhage in the medial area of the basal ganglia and 45 5% (5/11) in cases of preoperative brain hernia, respectively. Conclusions Small fenestration and hematoma clearance under local anesthesia is effective for hemorrhage under the cortex or in the lateral area of the basal ganglia and without brain hernia. Provided surgical treatment is early and adequate, the prognosis of cerebellar hemorrhage is excellent. Small incision trepanation with suction and drainage under local anesthesia exerts no appreciable effect on hemorrhage in the medial area of the basal ganglia.