AIM: To evaluate the relationship between eye dominance and hand preference among university students with respect to dominant hemisphere. METHODS: A total of 179 university students (mean age ±SD was 19.4±1.6 years) were included in the study. The subject population was composed of 110 females (61.5%) and 69 males (38.5%) volunteered for examina-tion. Eye dominance was determined by two different methods named Gündoan and McManus tests. Handed-ness was also determined by two different methods as Edinburgh Handedness Inventory Oldfield (1971) and McManus tests. The reliability of the survey was examin-ed using a test-retest method.RESULTS: Without gender difference right/left eye dominance were found respectively for 110 (61.5%), 69 (38.5%) subjects by Gündoan test. When the same subjects were re-tested by McManus method the right/left eye dominance was found respectively for 128 (71.5%), 51 (28.5 %). The results of these two methods were related significantly, with an agreement score κ=0.256 (P<0.01). In females the right/left eye dominance were found respectively as 62 (56.4%), 48 (43.6%) by Gündoan test as it was found respectively 74 (67.3%), 36 (32.7%) for the same subjects when re-tested by McManus test method. The results of these two tests for females were related significantly by Fisher exact test (P<0.05), with agreement score κ=0.239 (P<0.01). In males the right/left eye dominance were found respectively as 48 (69.6%), 21 (30.3%) in Gündoan test method as it was found 54 (78.3%), 15(21.7%) for the same subjects when re-tested by McManus test (P>0.05). Right handedness ratios were 91.6% (n=164) and 91.1% (n=163) in Oldfield and McManus tests, respec-tively. Statistical agreement between these two methods was also represented with a high score (κ=0.753, P<0.01). The statistical relationship correlation between eye dominance and throwing hand was found significant by McManus test methods (Fisher exact test P<0.017) with an agreement score phi=0.193, P<0.05.CONCLUSION: The marked right handedness was observed among university students in both two hand preference tests. According to McManus test the throwing hand seems to have more consistent relation with the right eye dominance. Throwing hand and dominant eye seems to be a most reliable way for detecting functional asymmetry and cerebral laterality.

AIM: To examine a new performance test for detecting eye dominance by testing and re-testing with two different methods of the same subjects for comparing and discussing the reliabilities of these tests. ·METHODS: A total of 179 university students (mean age±SD was 19.37±1.62 years) were voluntarily participate in this survey consisting of 110 females (61.5%) and 69 males (38.5%). Eye dominances were determined by two different methods which were named McManus examined using a test-retest method. ·RESULTS: Without sex difference right eyes were found dominant for 128 (71.5%) participants by McManus test. The right eye dominance were found for 110 (61.5%) subjects. The results of these two methods were related significantly by Fisher Exact test (P ＜ 0.01), with an agreement scores (κ=0.256, P＜ 0.001). In females the right eye dominance were found for 74 (67.3%) and left eye were found for 36 (32.7%) by McManus test. When the right eye dominance was found as 62 (56.4%); and the left eye dominance was found for 48 (43.6%) females were related significantly by Fisher Exact test (P＜ 0.05), with a weak agreement scores (κ=0.239, P ＜ 0.01). In males the right/left eye dominance were found respectively 54 (78.3%), 15(21.7%) in McManus test as it was found as 48 (69.6%), 21 (30.4%) for the same test and Fisher exact test were used for the analysis of categorical data. The agreement between different methods was analyzed with Kappa statistics. Comparison of proportions was made by two proportions z test. P value less than 0.05 was considered as significant. ·CONCLUSION: Without gender difference and also in both females and males marked right eye dominance was observed. The right eye dominance was considering functional laterality may due to the dominance of left hemisphere instead of right hemisphere. It is an important topic future research in laterality, and it may well become an important model system for future research.

AIM: To investigate the validity of computer-adapted Ishihara test and the concordance with classic Ishihara test for the diagnosis of colour blindness. The sensitivity and the specificity of computer-adapted Ishihara test and potential usefulness of the test for detecting congenital colour blindness or colour vision deficiency were discussed.METHODS: Colour vision of 104 university students aged between 20 and 23 (median 21) years was evaluated by two methods. These methods are: 1) Individual test method based on computer-adapted Ishihara colour plates; 2) Individual test method based on classic method of exposing Ishihara colour printed plates. The capabilities of students perceiving colours were evaluated by these two different methods. The specificity, concordance and validity for the computer adapted Ishihara test method were investigated.RESULTS: There were 6 male and 1 female colour blind students. The pedigree of the female student proved to have a carrier mother and colour blind father. The incidence of colour blindness was 13.6 % (6/44) among males and 1.7%(1/60) for females. The incidence of colour blindness in whole population was 6.7 % (7/104). These students had not been aware that they have colour vision deficiency before our examination tests. Test results of students with normal colour vision and the students with colour blindness were compared as well as the two test methods in terms of concordance. The sensitivity and the specificity were both found to be 100 %and concordance was also found 100 %.CONCLUSION: Computer-adapted Ishihara test is digitally mastered, and remains true with respect to the basic concepts of color vision testing. It has obvious advantages over manual testing because its total test time and its error scores are standardized. It has been found 100% in agreement with the golden standard of classic Ishihara test. These features make this test original and dependable one.

· AIM: To evaluate genetic characteristics of congenital color vision deficiency of our medical student and her family subjects for establishing the mode of inheritance.· METHODS: Ishihara Pseudo-isochromatic Plate Test (IPPT)was used for determining the color vision deficiency and Farnsworth 100 Hue test (F100HT) was done for evaluating the type of color vision deficiency. Family pedigree was established for the color blindness, ophthalmologic examinations and genetic studies were done. Genetic counseling was given to her family.· RESULTS: Ocular examination revealed best correction bilateral visual acuity of 20/20 in both eyes, with myopic correction (-2.0D). Slit-lamp examination and intraocular pressure measurement were within normal limits and funduscopy revealed normal optic nerve, macula and retinal periphery. All other external ocular assessment and neurological examinations were normal. Proband's sisters and her parents' ophthalmic examinations were also normal. The error scores of three sisters and their father were found 19-20/25 in IPPT. The results were consistent as deutran of red-green color blindness. The chromosome analyses and ovarian cycles were both normal.· CONCLUSION: According to her family pedigree, her color blindness was due to X-linked recessive penetrance mode of inheritance.

No abstract available.
Pregnancy* ; Purpura, Thrombotic Thrombocytopenic*

AIM: To evaluate genetic characteristics and clinical findings in a family with high myopia and colour vision deficiency (CVD).METHOD: Eight affected subjects of 42 members in four generations of the same family underwent a complete ophthalmic examination. Classical and computer adapted Ishihara Plates and Farnsworth-Munsell 100 Hue (FM100H)tests were used for determining the red-green CVD and full-field electroretinography (ERG) was performed to evaluate retinal function.RESULTS: Eight affected subjects had subnormal visual acuity due to high myopia. The results of colour vision tests were consistent with red-green CVD in six of these affected subjects. Fundus examination showed degenerative myopic changes characterized with generalized chorioretinal atrophy.Abnormal cone and rod dark-adaptation and diminished cone response in ERG were found in two subjects. According to family pedigree, it has been suggested that red-green CVD has X-linked recessive inheritance.CONCLUSION: The concurrence of high myopia with CVD in the members of this family may show a possible evidence for an associate genetic basis on different disorders.

This study aims to assess knowledge, attitude and behavior in sexual and reproductive health (SRH) including comprehensive sexuality education (CSE) among 439 first year students; 213 sciences and 226 arts students from 5 Faculties of University Malaysia Sabah (2016-2017). Exposure of Malaysian students to sexual education is limited to science subjects which are only being taught at upper elementary and secondary high school levels. Arts students are less exposed to sexual education across Malaysia as it is delivered in Basic Science subject only. It was a university-based, cross-sectional, descriptive study. Pretested self- administered questionnaire was anonymously completed by all participants and was conducted from November 2016 to January 2017. Students’ demographic characteristics from Science and Arts streams were same except females, Sabah ethnics and Malays were more in Arts. Awareness of HIV/AIDS, Condom, Wet dream, COC pills and abortion services were more in Science students and statistically significant. 34.3 % and 81.2% of Science students agreed that CSE should be introduced in primary and secondary school but not statistically significant. 22 out of 439 students were sexually active. Science students had more knowledge about SRH and favourable attitude towards sexuality education but less favourable behaviour of watching and reading pornographic materials. It was concluded that there were gaps in knowledge, attitude and behaviour of SRH and need to remedy these by giving appropriate CSE classes to first-year university students in an elective module according to their culture and religious beliefs in accord with International Technical Guidance on Sexuality Education (ITGSE).

During the past two decades, management of blunt solid organ injuries had shifted from conventional surgery to more conservative approach, namely nonoperative management (NOM).[1] The non-operative approach mainly depends on the trauma experience of surgeons and the institution, quality of radiographic imaging and its interpretation.[2-5] If the surgeon decides to observe the patients by NOM, close monitoring of vital signs and frequent physical examinations must be done accordingly with radiological evaluations if needed.

BACKGROUND: Airborne particulate pollution is more critical in the developing world than in the developed countries in which industrialization and urbanization are rapidly increased. Yangon, a second capital of Myanmar, is a highly congested and densely populated city. Yet, there is limited study which assesses particulate matter (PM) in Yangon currently. Few previous local studies were performed to assess particulate air pollution but most results were concerned PM alone using fixed monitoring. Therefore, the present study aimed to assess distribution of PM in different townships of Yangon, Myanmar. This is the first study to quantify the regional distribution of PM in Yangon City. METHODS: The concentration of PM was measured using Pocket PM Sensor (Yaguchi Electric Co., Ltd., Miyagi, Japan) three times (7:00 h, 13:00 h, 19:00 h) for 15 min per day for 5 days from January 25 to 29 in seven townships. Detailed information of eight tracks for PM pollution status in different areas with different conditions within Kamayut Township were also collected. RESULTS: The results showed that in all townships, the highest PM concentrations in the morning followed by the evening and the lowest concentrations in the afternoon were observed. Among the seven townships, Hlaingtharyar Township had the highest concentrations (164 ± 52 μg/m) in the morning and (100 ± 35 μg/m) in the evening. Data from eight tracks in Kamayut Township also indicated that PM concentrations varied between different areas and conditions of the same township at the same time. CONCLUSION Myanmar is one of the few countries that still have to establish national air quality standards. The results obtained from this study are useful for the better understanding of the nature of air pollution linked to PM. Moreover, the sensor which was used in this study can provide real-time exposure, and this could give more accurate exposure data of the population especially those subpopulations that are highly exposed than fixed station monitoring.
Air Pollutants ; analysis ; Cities ; Environmental Monitoring ; Myanmar ; Particulate Matter ; analysis

Marine sponges of the genus are well known as rich sources of diverse and complex biologically relevant natural products, including alkaloids, terpenoids, peptides, lipids, and steroids. Some of these metabolites, with novel structures and promising biological activities, have attracted a lot of attention from chemists seeking to perform their total synthesis in parallel to intensive biological studies towards new drug leads. In this review, we summarized the distribution of the chemically investigated sponges, the isolation, synthesis and biological activities of their secondary metabolites, covering the literature from 1982 to early 2018.