Child ; Child Welfare ; trends ; China ; Humans

0.05).While the diagnosis ratio of MP and LP with RT-PCR+IIF method were higher than any of other 3 methods significantly(Pa

Female ; Humans ; Hyperthyroidism ; drug therapy ; etiology ; Infant, Newborn ; Male

Objective To study the surgical treatment of nodular goiter.Methods The surgical treatment effects of 248 cases with nodular goiter were reviewed.Results 123 paitients were cut off the merely nodle,83 patients suffered one side subtotal lobectomy,32 patients suffered doublr subtotal lobectomy, 10 patients suffered one side merely nodle plus oppside subtotal lobectomy, and 12 patients received operations twice,including 1 case (temporarily) of permanent injury of parathyroid, 1 case(temporarily) of injury of recurrent laryngeal never,3 cases of postoperative hemorrhage.All patients were followed up from 1 to 8 years,and no relapse was noted after operation.Conclusion One side thyroid gland nodle or nodles should cut off the merely nodle and it is unneceeary to deal with the blood vessel of the thyroid up and down,one side or double side thyroid gland nodles tightly should operated subtotal lobectomy, to ligate the blood vessel of the thyroid down, not to dispose the recuyyent laryngeal nerve,reserving the left over gland in cyst,and to prevent hypothyroidism and recurrent laryngeal nerve.

Objective To explore the trend of Th_1/Th_2 bias in Hashimoto thyroiditis(HT)and their effects on the pathogenesis of HT.Methods The proportion and mean fluorescence intensity(MFI)of CCR5 and CD30 were examined on peripheral T lymphocytes by flow cytometry in patients with Hashimoto thyroiditis(HT)(n=21)and healthy controls(n=45).Results The proportion of both CD4~+CCR5~+and CD~+4 CD30~+ cells were significantly increased in HT group(P

Objective To investigate the expression o f telomerase activity in pheochromacytoma and to assess its utility as a prognos tic marker. Methods Telomerase activity was estimated in 23 samples of pheohromocytoma tissue and 6 samples of normal adrenal medullae by autoradiography-based telomeric repeat amplification protocol. The reaults w ere analized with follow-up findings. Results Of the 2 3 pheochromocytoma samples, 2 had telomerase activity and both the telomerase-p ositive pheochromocytomas apparently arose from extraadrenal tissues. All normal adrenal medullae samples were negative for telomerase activity. During follow- up, we found both of the telomerase positive patients developed mutiple metastat ic lesions after surgery. Only one of 21 telomerase negative patients clinically developed bilateral lung metastases and a local recurrence after surgery. Conclusions Telomerase activity may be used as an important i ndicator of potentially malignant pheochromocytoma and may serve as a prognosti c marker.

Objective To evaluate the short term results of shoulder hemi-arthroplasty. Methods Twenty-one patients with comminuted intra-articular fracture of proximal humerus underwent Neer type (Link, Germany) humeral head replacement from August 2000 to January 2004, which involved 5 males and 16 females,with an average age of 70 years (range, 64-76 years). According to AO M?ller classification, 3 cases were of C1 type, 8 C2 type, and 10 C3 type. The important steps of the procedure included insertion of the prosthesis in 40 degree retroversion and reconstruction of the rotary cuff of shoulder. The rehabilitation training course was divided into three stages. The patients were trained passively in the first stage (1 day-6 weeks); The muscles around the shoulder undertook isometric contraction once the bone fusion of greater and lesser tuberosity were obtained on X-ray for the second stage (7 -12 weeks); The improvement of the muscle strength and ROM of the shoulder were targeted throughout the third stage (13-24 weeks). All cases were followed up with Neer's scoring system comprising the symptoms, function, range of motion (ROM) of shoulder, and position of the prosthesis. Results The follow-up was performed twice a month within one year postoperatively, and one time three months after that.The mean duration of follow-up was 34.5 months (range, 14 to 55 months). Only slight pain was complained occasionally in 4 cases. No difficulty in active daily life was found in 21 cases .The average ROM of shoulder was flexion 115?(range, 65?-165?),extension 42.5?(15?-70?),abduction 85?(50?-120?), adduction 32.5?(20?-45?), external rotation 40?(20?-60?),and internal rotation 50?(10?-90?). No dislocation or subluxation of shoulder occurred in all cases. Assessed by Neer's scoring system, 8 cases were rated as excellent, 9 as good, 3 as fair and 1 as poor. The excellent and good rate was 80.9%. The patients' satisfactory rate was 90%. Conclusion The shoulder hemi-arthroplasty show good short term results for comminuted intra-articular fractures of the proximal humerus. The key points to improve the postoperative results are presented as follows: less invasive technique, appropriate retroversion angle for humeral head prosthesis, very solid reconstruction for rotary cuff of shoulder, and correct consecutive physical therapy after surgery.

Objective Attempting to find a reliable method for assessing the patient's ability to tolerate carotid artery occlusion. Methods The temporary balloon occlusion (TBO) test of carotid artery was performed for 20 patients who might have carotid artery manipulated or permanently occluded. Transfemoral artery Seldinger's catheterization was used to introduced the temporary balloon occlusion catheters into the vessels of the concern. Neurologic testing was performed continuously by the attending neurologist. Transcranial Doppler ultrasonography (TCD) and carotid artery stump pressure (SP) were measured contiuously during the TBO. The collateral circulation of Willis circle was observed with DSA. Results Out of the 20 cases, one failed during the TBO because of CCA dissection caused by catheterization, another one failed because of a neurologic defect occurring before the balloon was inflated, the others went through the test uneventfully. Two cases finished the test before the approved schedule because neurologic defects appeared 34 min and 27 min after the vascular occlusion, respectively. These two patients were proved unable to tolerate carotid artery sacrifice. The other 16 cases passed the 45 minutes TBO. Their mean velocity of ipsilateral middle cerebral artery fell 36%?18%. Their SP is (53.76?21.49) mmHg(30-87). Adequate collateral circulation in Willis circle was observed by DSA in all cases except the two who failed with the TBO. Conclusions TBO is a safe and reliable method for assessing the patient's ability to tolerate carotid artery occlusion. We suggest it should be a routine examination prior to carotid manipulations.

Traditional Chinese medicine (TCM) is the treasure of the Chinese nation civilization. Along with China acceding to WTO, the grandness of international natural drug market and its accepting of Chinese materia medica (CMM), CMM industrialization in China gets the opportunity growing quickly. But it is faced with many challenges from all over the world.This article introduces the theory of industria-lization competitiveness, which was put forward by Pro. Michael E. Porter, Harvard University, and applied “diamond model” theory to evaluating the international competitiveness of the CMM industrialization of China. The analysis will provide the base for establishing the strategy for the development of the CMM industrialization in China and upgrading its international competitiveness.

Objective To assess the histopathological characteristics of tumors arising in nevus sebaceous.Methods The clinical and pathological data on 16 patients with tumors arising in nevus sebaceous were collected and retrospectively reviewed.Histopathological characteristics were analyzed.Results Of the 16 patients,12 aged ≥ 18 years,4 aged 11 to 17 years; 7 had syringocystadenoma papilliferum(SCAP),4 tubular apocrine adenoma (TAA),3 trichilemmoma,2 basal cell carcinoma (BCC),1 porokeratotic eccrine ostial and dermal duct nevus,and 1 nevus flammeus.Six patients suffered from more than one kind of tumor,of these tumors,concurrent syringocystadenoma papilliferum and apocrine adenoma predominated and were observed in 4 of these patients.Conclusion Any tumor arising from nevus sebaceous should be closely followed up.