No abstract available.
Humans ; Infertility, Male* ; Male ; Male*

No abstract available.
Humans ; Infertility, Male* ; Male ; Male*

The goals of the evaluation is to identify; 1) potentially correctable conditions, 2) irreversible conditions but are amenable to ART using male partner sperm, 3) irreversible conditions not amenable to ART, fro which donor IUI or adoption are possible options, 4) life- or health threatening conditions that may underlie infertility and require medical attention and 5) genetic abnormalities that may affect offspring if ART is employed.
MALE ; INFERTILITY ; INFERTILITY, MALE

No abstract available.
Biopsy* ; Humans ; Infertility, Male* ; Male ; Male*

No abstract available.
Humans ; Infertility* ; Infertility, Male* ; Male ; Male*

Rhinoscleroma, or scleroma, is a chronic, slowly progressing granulomatous disease involving the upper respiratory tract, especially the nasal vestibules, choanae, pharynx, and larynx. Almost certainly the causative agent is Klebsiella rhinoscleromatis. The disease occurs frequently in Eastern Europe, the Middle East, and parts of Latin America, but it is hard to find such case in Korea. We prisent a case of rhinoscleroma involving the nasal vestibule in a 18-year-old male who was admitted due to nasal obstruction for 5 years and epistaxis for 2 months. The resected specimen was an irregular polypoid mass with relatively firm consistency and measured 3 cm in the largest diameter. Microscopically, the lesion was characterized by extensive fibrosis and inflammatory cell infiltration. The infiltrates consisted of predominantly lumphocytes, plasma cells, foamy or granular histiocytes which were singly scattered or grouped in clusters. In the cytoplasm of the histiocytes, round slightly basophilic bodies were noted. Warthin-Starry satin showed short positive rods within the cytoplasm of the cell (Mikulicz cell). Electron microscopically, the cytoplasm of Mikulicz cells contained large, round or irregular shaped clear vacuoles in which numerous Klebsiella bacilli attached to the boundaries of the vaculoes were noted. With higher magnifications, the bacilli were seen as roung or rod-shaped organisms.
Male ; Humans

PURPOSE: The aim of this study was to evaluate the effect of periurethral prostatic calculi on lower urinary tract symptoms(LUTS) at the initial visit and after treatment with an alpha-blocker in benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: A total of 223 male patients with LUTS were studied. Group 1 consisted of 81 patients with periurethral prostatic calculi within 5 mm from the prostatic urethra of the transitional zone, as determined by transrectal ultrasound. Group 2 consisted of 142 patients without periurethral prostatic calculi within 5 mm from the prostatic urethra. The International Prostate Symptom Score(IPSS), maximal urinary flow rate (Qmax) and post voided residual urine(PVR) were measured in patients of both groups at the beginning of the study and at eight weeks after the treatment with 4 mg doxazosin gastrointestinal therapeutic system (GITS). RESULTS: Voiding, storage and the total IPSS for Group 1 patients were higher than for Group 2 patients(p>0.05). Quality of life(QoL), Qmax, and PVR were not significantly different at the initial visit. After treatment with 4 mg doxazosin GITS, an improvement of voiding, storage and the total IPSS for Group 2 patients was seen as compared to Group 1 patients (p<0.05). The mean improvement of QoL was 0.44+/-0.73 for group 1 patients and 1.13+/-0.82 for group 2 patients(p<0.001). The mean change of Qmax was 1.02+/-1.40 ml/sec for Group 1 patients and 1.52+/-1.84ml/sec for Group 2 patients(p=0.035). Changes of PVR were not significant between the two groups. CONCLUSIONS:This study suggests that the periurethral prostatic calculi may aggravate lower urinary tract symptoms and decrease the effect of alpha- blockers.
Male ; Humans

PURPOSE: Gynecomastia is a common male breast abnormality and primarily occurs in puberty and senescence. The obvious etiological role of hormonal changes in gynecomastia, plus the discovery of estrogen receptor in normal and neoplastic breast, has spurred several investigations of ER content in male gynecomastic tissues. The results have been inconsistent and the fraction of ER-positive specimens has varied from 0~90%. METHODS: Immunohistochemical hormonal receptor analysis using monoclonal estrogen receptor (ER) alpha, beta and progesteron receptor (PR) was performed on the breast tissues of 58 patients with gynecomastia between January 1995 and January 2000 in the Department of Surgery, Uijongbu St. Mary's Hospital. These results were statistically compared with clinical data. RESULTS: 48 cases (82.8%) were ERalpha positive and 55 cases (94.8%) were ERbeta positive and PR positivity was noted in 55 cases (94.8%). There was negative relationship between ERalpha and age, PR and location. CONCLUSION: This study demonstrates that intracellular steroid receptors are present in most gynecomastic tissues. Additionally, it supports the general assumption that estrogen and progesteron may be two of the hormones responsible for the development of gynecomastia.
Male ; Humans

OBJECTIVE: Clozapine is known as an atypical antipsychotic drug which has less side effects in the extrapyramidal system than typical antipsychotic drugs and recommended as a treatment of choice in severe tardive dyskinesia (TD). However, it has been reported that the existing TD was worsened or new TD appeared in some cases where the antipsychotic drugs were switched to clozapine. METHODS: We experienced a single case in which TD was appeared in the tongue and jaw 5 months after chlorpromazine was switched to clozapine. RESULTS: The subject was 57 years old male patient with bipolar disorder. He had been treated intermittently with lithium and chlorpromazine for over 30 years. Five months after switching from chlorpromazine to clozapine, TD appeared in the tongue and jaw. Using Extrapyramidal Symptom Rating Scale (ESRS), the dyskinesia score was 10. Hence, clozapine was stopped and chlorpromazine was re-administrated resulting gradual improvement of TD. The dyskinesia score of ESRS was dropped to 6. CONCLUSION: It is speculated that this case is most likely a withdrawal tardive dyskinesia but other possibilities should be considered too. The question "Does withdrawal tardive dyskinesia occur more easily when switched to clozapine which has a weak dopamine antagonism?" should be addressed in future study.
Male ; Humans

Anterior mediastinal teratoma was removed from the right hemithorax of a 15-year-old male patient presenting initially with right chest discomfort and hemoptysis. He was died following precipitous clinical deterioration, 2 months after open thoracotomy. The true malignant nature of this tumor, that there are endodermal sinus tumor and squamous cell carcinoma, was apparent on resection specimen. The former had metastasized to right supraclavicular lymph node. A similar case has not been reported previously on the review of the pertinent literature on malignant mediastinal teratoma.
Male ; Humans