Upper case Bee ; Therapeutic procedure ; Hepatitis, Chronic

With 22 patients hospitalized in the Rehabilitation Center of Okayama Prefecture the oxygen metabolism of physical hanlicapped was investigated. These subjects were composed of 8 cases of poliomyelitis, 4 cases of cerbral palsy and others. The results are briefly summarized in the following :
1. In general the basic metabolism is at the lower limit of the normal level.
2. Generally speaking, the relative metabolic rate (RMR) is high in the gait of those handicapped with lower extremeties, and this is especially so in cerbral palsy.
3. The reason of a markedly low RMR in poliomyelitis when using the affected limbs for work lies in the fact that the patient is not working diligently.
4. The labor index (RMR × minutes) per day proved to be 400-1, 300.
5. The total calory consumption per day was between 1, 100 and 2, 400 Calories, and in the four cases whose calory consumption exceeded over 2, 200 Calories of the diet given, they were supplementing themselves with the food of their own choice.

The purpose of this study is to inquire histologically when red muscle fibers and white muscle fibers are differenciated and how they develope, considering from sex difference.
Wistar-strain rats of the same venter were used in this experiment. The animals of both sexes were killed at the interval of five days, from birth to 25 days. Two groups of male and female rats of 70 days old after birth were used as control groups.
M. tibialis ant. was removed and then fixed in 10% formalin for approximately two weeks. As staining, alchohol solution of Sudan black B was used.
The results are as follows :
1) Sex difference in rats' body weight was started to appear about 15 days after birth.
2) Differentiation of red muscle fibers and white muscle fibers in M. tibialis ant. was recognized about 15 days after birth in male and female rats.
3) The entire area of cross section of M. tibialis ant. is increasing during the development of rats' body as a whole. No apparent tendency on sex difference was found till 25 days after birth. On 70 days after birth the entire area of cross section in male has about 1.5 times the size of female.
4) No increase of number in M. tibialis ant. was recognized during the development of rats' body as a whole and no sex difference in number of muscle fibers.
5) The area of cross section per fiber and the average diameter of fibers are increasing during the growth of rats' body. No sex difference of those in red and white muscle fibers was found till 25 days after birth but, on 70 days after birth, it became clear. The rate of hypertrophy of white muscle fibers is greater than that of red muscle fibers.
6) Ratio of the entire area of muscle fibers to the intercelluler space in M. tibi-alis ant. is increasing during the development of rats' body.
7) No difference of area of cross section per fiber in peripheral and innermost regions was found till about 15 days after birth. On 70 days after birth the red muscle fibers in peripheral have 1.4 times the size of those in innermost, and the white muscle fibers 1.3 times.