Arteriosclerosis Obliterans ; surgery ; Humans ; Lower Extremity

Objective To evaluate the effects of a health education project on prevention and control of iodine deficiency disorders.Methods From January to June 2011,an investigation was conducted using combined unified questionnaire in 9 counties on target population,and 3 townships were chosen in each project county.Health educational activities were carried out in grade 5 classes in the central primary school.In the meantime,3 villages were chosen in each selected township where the health educational activities in the community were carried out.Before and after the health educational activities,questionnaire surveys on knowledge of iodine deficiency disorders were conducted in each project county.Thirty students in one class of grade 5 in the central primary school were selected,and 15 women of childbearing age near the central primary school were selected too.The health education content included but not limited to:popular science films about the knowledge on endemic disease prevention and public-interest ads were broadcasted by radio,television,newspapers and other media in the project counties,aiming at spreading knowledge on prevention and treatment of endemic diseases.In each of the project township government and village committee locations,posters,banner pieces and slogan suspensions about knowledge on endemic disease prevention were posted or put up.In the project rural hospitals,a special bulletin boards was set up,and in the village clinics (rooms),posters were put up,to carry out a training program for women of childbearing age on endemic disease prevention.In primary schools,students in grades 4 to 6 were given a class about knowledge on prevention and treatment of iodine deficiency disorders,aiming at their transferring the learned knowledge to family members.Results A total of 2678 persons were investigated before and after the health education.After health education,the rate of knowledge(the correct answer rate) on iodine deficiency disorders increased from 69.04％ (1920/2781) to 94.08％ (2622/2787,x2 =580.63,P ＜ 0.05) among primary school students,and 74.76％(924/1236) to 92.60％(1139/1230,x2 =143.59,P ＜ 0.05) among women of childbearing age.Conclusions The rate of knowledge awareness in the students and the women of childbearing is increased significantly after the health educational activities.Systematic and targeted health education activities are effective measures in prevention and control of iodine deficiency disorders.

Animals ; Feasibility Studies ; Female ; Mice ; Mice, Inbred BALB C ; Plethysmography ; methods ; Tidal Volume ; physiology

Abdomen ; pathology ; surgery ; Anemia ; complications ; Castleman Disease ; complications ; diagnosis ; Child ; Humans ; Lymph Nodes ; pathology ; Male ; Treatment Outcome

Objective To analyze the levels and speciation of arsenic metabolites in urine of rats treated with sodium arsenite and sodium arsenate in order to investigate the different aspects of metabolism between sodium arsenite and sodium arsenate,thus to understand further the basic data about relationship between it's metabolism and mechanism of toxicity. Methods Seventy Wistar rats,weighting 80-120 g,were divided into 7 groups of 10 each,such as normal control group,high,middle and low sodium arsenite group and high,middle and low sodium arsenate group. After the animals were fed for one month,the urine was collected by metabolic cage in 12 hours. Applying the high efficiency liquid chromatography and hydride genesis atomic fluorescence spectroscopy (HPLC-HGAFS),the levels and speciation of arsenic metabolites were determined in urine of rats. Meanwhile,the recovery rate of dimethyl arsinic acid(DMA) would be determined to estimate the degree of accuracy of results. Results The levels of iAs~(3+),iAs~(5+) and DMA in middle sodium arsenite group[(121.66±1.26),(10.26±2.68),(200.91±0.56) μg/L]were higher than the high sodium arsenite group[(113.20±0.75),(5.16±1.32),(147.70±μ0.77)μg/L,all P < 0.05]and low sodium arsenite group[(79.35±2.12),(5.13±2.25),(56.35±1.23)μg/L,all P < 0.05]. The levels of iAs~(3+) and DMA in middle sodium arsenate group[(315.81±1.69),(245.12±1.18)μg/L]were higher than the high sodium arsenate group[(85.03±0.56),(110.34±1.04)μg/L,all P< 0.05]and low sodium arsenate group[(22.97±2.67),(15.75±2.15)μg/L,all P < 0.05]. Compared with sodium arsenate group,the levels of iAs~(3+) and DMA in high and low sodium arsenite group were higher(all P < 0.05) ; and the levels of iAs~(3+) and DMA in middle sodium arsenite group were lower(all P < 0.05). Meanwhile,the average urinary recovery rate of DMA of rats in different sodium arsenite group were 94.80%-102.70%,and the average urinary recovery rate of DMA of rats in different sodium arsenate group were 95.33%-108.40%. Conclusion The speciation and levels of arsenic are influenced by the external exposure dose,and some distinction appeared in the metabolism and metabolic path between sodium arsenite and sodium arsenate in urine in vivo.

Humans ; Stem Cell Transplantation ; Tissue Engineering ; trends ; Wound Healing

Gas Chromatography-Mass Spectrometry ; Solvents ; analysis ; chemistry ; Volatile Organic Compounds ; analysis ; chemistry

Cerebrum ; pathology ; physiopathology ; Congenital Abnormalities ; physiopathology ; Humans ; Infant, Newborn ; Male ; Neonatology ; Osteopetrosis ; complications ; physiopathology ; Research Report ; Telencephalon ; abnormalities

Air Pollutants, Occupational ; analysis ; Solvents ; analysis

Objective To analyze clinical common pathogenic bacteria distribution of neonatal sepsis and antimicrobial resistance ,in order to provide theoretical basis for clinical rational use of antibiotics .Methods 342 cases of neonatal sepsis were selected as the research objects ,through the case control study ,specimens were collected retro-spectively the clinical data and blood culture ,to understand the pathogenic bacteria children with neonatal septicemia culture,To understand the pathogenic bacteria in children with neonatal septicemia culture .Distribution and drug resistance of pathogenic bacteria were analyzed .Results 342 cases of neonatal septicemia infection rate was 5.4%, among the 136 cases of preterm infants with sepsis ,infection rate is 10.9%,206 cases of full-term infants with sep-sis,infection rate was 4.0%, Septicemia in premature infants infection than full -term sepsis (χ2 =88.07, P <0.01);No significant difference of septicemia in premature infants and full -term infants septicemia pathogen strain distribution(P>0.05).Coagulase negative Staphylococcus aureus and Staphylococcus aureus resistant to penicillin , drug resistance rates were 97.1% and 87.5%,secondly to erythromycin resistance ,respectively were 86.9% and 75.0%;Three kinds of common gram negative bacteria were sensitive toimipenem ,resistance to ampicillin and cefazo-lin,drug resistance rate was 100.0%,the second was piperacillin ,cefepime,cefotaxime and ceftazidime .Conclusion Neonatal septicemia of gram positive bacteria mainly coagulase negative Staphylococcus aureus and Staphylococcus aureus,gram negative bacteria mainly in grams of Klebsiella pneumoniae , Escherichia coli and Escherichia coli . Common pathogenic bacteria with drug resistance .Clinical treatment of neonatal sepsis should be rational use of anti -biotics,to strengthen the monitoring of drug resistance .