1.Study on Relative Bioequiavailability of Telmisartan Capsules in Healthy Subjects
China Pharmacy 2001;0(10):-
0.05).The relative bioavailability of experimental preparation vs.reference preparation was(93.80?12.24)%.CONCLUSION:Telmisartan capsule has the same bioe-quiavailability with telmisartan tablet.
2.Establishment, monitoring and improvement of indicators of specimen quality in clinical laboratories
Chinese Journal of Laboratory Medicine 2016;(1):10-12
The pre-examination process is the first key step in the total testing process of clinical laboratories.Specimen acceptability is an important indicator to measure the quality of pre-examination.In order to identify the risks and the root causes in the process , establishment and monitoring of quality indicators about specimen will effectively control the risks , enhance the acceptability of specimens , promote the improvement of pre-examination quality and finally get the aim of assuring patients′safety.
3.Pay emphasis to the diagnosis and treatment of flat tumors of colon
Medical Journal of Chinese People's Liberation Army 2001;0(11):-
Flat colon lesions, which include superficial colon tumor and depressed colon tumor, have close relationship with colon cancers. The main type of flat colon tumor is laterally spreading tumor (LST) while the main type of depressed tumor is depressed early colon cancer (IIc type). Little has been reported about the flat colon tumor because it is difficult to be detected and has not yet been broadly recognized by clinicians. Recently, clinicians with the Nanfang Hospital have innovated some novel colonoscopic approaches to improve the diagnosis and treatment of flat colon tumor and accumalate experiences in this regard. Their conclusions are: 1. Improvement in recognizing the physical characteristics of the lesion and the application of chromoscopic colonoscopy are the key points to reveal and identify the flat colon tumors. 2. The best theraputic methods for flat colon lesions are endoscopic mucosal resection and piecemeal endoscopic mucosal resection.
4.Study on quick extraction and determination of icariin from Herba Epimedii
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(01):-
Objective: To study the quick extraction and determination of icariin in Herba Epimedii.Methods: The orthogonal design and ASE300 system were used to study the extraction method of icariin.The content of icariin was determined by HPLC.The methanol water glacial acetic acid(60∶40∶0.25) was used as a mobile phase. The flow rate was 1.0ml/min,the detection wavelength was 270nm and the column temperature was 41℃.Results: The optimal extraction conditions were: 50% alcohol and extracting one times for twenty minutes each time at 70℃.The extracting rate of icariin was 93.15%.The RP-HPLC for determining method is simple,rapid and accurate.Conclusion: The extraction and determination methods are practicable for icariin in Herba Epimedii.
5.OBSERVATIONS AND MEASUREMENTS OF THE CEREBELLAR ARTERIES
Acta Anatomica Sinica 1954;0(02):-
Cerebellar arteries and their branches injected with red latex were observed on 50 adult human brains with the naked eye and stereomicroscope. The external and internal diameters of the arteries and the thickness of their walls were measured.According to the distribution, we named the middle inferior cerebellar artery as anterior inferior cerebellar artery, and the long stem type of the anterior inferior cerebellar artery as the posterior infericr cerebellar artery. So that, there are only three pairs of cerebellar arteries: the superior, the anterior inferior and the posterior inferior arteries. Each of the three arteries may be single-branched double-branched or wanting. So the number of the cerebellar arteries is inconstant. The origins of these arteries are variable and the majority of the abnormal sites of origin are situated adjacent to the normal site rostrally. The arterial distributions on both sides are mostly unsymmetrical. These arteries anastomose with each another. If the anterior inferior cerebellar artery is absent the other two arteries of the same side compensate for its loss. While the posterior inferior cerebellar artery is absent or thin it will be compensated for not only by the others of the same side but also by the branches from the corresponding artery of the opposite side. Concerning the diameter of these arteries, the superior cerebellar artery is the largest; the posterior inferior cerebellar artery comes next and the anterior inferior cerebellar artery is the smallest. The blood flow of the inferior surface of the cerebellum, supplied by the posterior inferior artery together with the anterior inferior artery is more abundant than that of the superior surface supplied only by the superior artery.Posterior inferior cerebellar arteries may be classified into two types:deep situated and superficial siluated types. The latter takes 36.8%. It can easily be found and safely operated when performing the operation of anastomosing the posterior inferior cerebellar artery with the occipital artery.
6.Content Determination of Paeoniflorin in Blood Plasma with Reversed-phase High-efficiency Liquid Chromatography
Chinese Traditional Patent Medicine 1992;0(02):-
The method, established for analysis of paeoniflorin in blood plasma, appeared a good linear relationship(r=0.9998). Using meta-hydroxybenzoic acid as internal standard and calibration factor combined, the quantitation precision of method could be raised. The result of determination of calibration factor conformed with the chromatography prescriptions in "Pharmacopoeia of China" (edited in 1990). The average recovery reached up 97.13%. The minimum detection amount was 5.6ng. The coefficients of within-day and between-day variation were 0.39% and 1.17%, respectively. This method is suitable for paeoniflorin analysis of in vivo sample . At present,the in vivo absorption of Baihegujintang Granules (containing Radix Paeoniae alba or Radix Paeoniae rubra) by rabbit is preliminarily investigated utilizing this method.
7.HPLC Determination of Main Nucleoside and Nucleic Acid Base in Mycelia of Cordyceps
Chinese Traditional Patent Medicine 1992;0(05):-
Six nucleosides and base components in Four products of Mycelia of cultivated Cordyceps were determined. The comparison of extraction solvents and recovery test of the adenosine components were emphasized. The effective extraction-rate by water,as an extraction solvent, was higher than that by 50% alcohol. The addition of 0. 1% sodium azide into water could not only preserve putrefaction,but also make a contribution to the stability of nucleoside components in the liquid sample. When the extraction was carried out by ultrasonic at room temperature,the recovery rate of the added sample was 99. 8%.
8.An observation on clinical efficacy in fibromyalgia syndrome
Chinese Journal of Rheumatology 2003;0(12):-
Objective To compare the efficacy between basic treatment, amitriptyline, and basic treatment combined with mirtazapine and total glucosides of paeonia (TGP) capsule in 4 groups of patients with fibromyalgia syndrome (FS). Methods The change of the pain before the treatment, one-month and three-months (after) treatment were analyzed by Visual Analogue Scale (VAS), Symptom Checklist 90 (SCL-90), Hamilton Anxiety Scale (HAMA), and Hamilton Depression Scale (HAMD). Results ① The scores of SCL-90 in group B was significantly lower than group A (P
9.Treatment of NH_3~-burned patients complicated with inhalation injury
Journal of Medical Postgraduates 2004;0(02):-
Objective: To investigate the management of NH~-_3 burned cases with inhalation injury. Methods:The clinic treatments of 15 NH~-_3 burned cases complicated with inhalation injury in his hospital between January 1998 and April 2004 were analyzed retrospectively.His management included reasonable fluid therapy,prompt and efficient usage of antibiotics ,tracheotomy after diagnosis,mechanical ventilation,bronchoalveolar lavage using fibrobrochoscope after the shock period and short-time usage of glucocorticoid. Results: Of the 15 cases,14 patients were cured and 1 patient was improved without any death.The cure rate was 93.3%. Conclusion: All of the managements should be performed as quickly as possible.Paying much attention to prevent the complications could improve the cure rate.Tracheotomy and bronchoalveolar lavage in the early stage are vital to patients.
10.Study on microwave-assisted extraction of magnolol and honokiol in Magnolia offcinalis Rend et Wils
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(11):-
Objective:To study the microwave-assisted extracting method for magnolol and honokiol in Magnolia offcinalis Rend et Wils.Methods:The orthogonal design was used to study the extraction method of magnolol and honokiol.The contents of them were determined by HPLC.The methanol water glacial acetic acid(85:15:0.25)was used as a mobile phase.The flow rate was 1.0ml/min,the detection wavelength was 294nm and the column temperature was 23℃.Results:The condition of 75%ethanol with the middling power of microwave,extracting for 4 minutes and ratio of materials to liquid 1:40 was the optimal extracting method.The extracting rate of honokiol and magnolol was 92.33%,73.59%.The RP-HPLC for determining method was simple,rapid and accurate.Conclusion:The extracting and determining method was practicable for magnolol and honokiol in Magnolia offcinalis Rend et Wils.