Objective To understand the status quo of health education requirement of cervical cancer patients undergoing chemotherapy, in order to take individualized health education to improve the quality of life of patients, as well as provide basis for hospitals to conduct targeted health education. Methods 68 cases of cervical cancer patients with chemotherapy were investigated with health education questionnaire. Results Cervical cancer patients with chemotherapy were in general needs of health education, to understand the treatment protocol and effect came to the first place of strong demand. Patients with different times of hospitalization, different age had different emphasis point for health education needs. The most popular education style was oral education. Conclusions Cervical cancer patients with chemotherapy lack knowledge of health education, they hope to obtain health education about examination, treatment and rehabilitation. Nurses should give targeted, planned and individualized health education in order to meet the health needs of patients and improve their quality of life.

OBJECTIVE: To investigate the effect of Compound danshen dripping pills on cytochrome CYP1A2 activity for reference of clinical rational drug use. METHODS: The contents of four major metabolites of Caffeine, i.e. 5-acetylamino-6-formylamino-3-methyluracil(AFMU),1-methylxanthine(1X), 1-methyluric acid(1U) and 1, 7-dimethyluricacid (17U) in the urine before and after oral administration of Compound danshen dripping pills were determined by RP-HPLC. The activity of cytochrome CYP1A2 was derived from the ratio of (AFMU+1X+1U)/17U. RESULTS: The average activity of CYP1A2 was 4.20?1.54 before medication, which stood at 4.26?1.95 at 14 days and 4.35?1.26 at 28 days after medication, up 1.42% and 3.57%, respectively, yet there was no significant difference after medication as compared with before medication. CONCLUSION: No significant difference was noted on CYP1A2 activity after oral medication of Compound danshen dripping pills, nor does it modify the efficacy of the concurrent drugs that metabolized by CYP1A2.

The role of bulletin in subject information service was analyzed, followed by a description of the con-tents, columns, topic selection standards and principles in Bulletin of Global Pharmaceutical Innovation, and a summary of the experiences in subject service through the bulletin.

BACKGROUND:The incidence rate of cervical abnormalities of the patients with skeletal class Ⅱ and normal occlusion has been studied abroad, but the researches on the incidence of cervical abnormalities in different malocclusion patients is rare at home. OBJECTIVE:To observe the imaging of patients with cervical abnormalities and to statistics the incidence of cervical abnormalities in different malocclusion patients through analyzing the lateral cephalogram of different malocclusion patients. METHODS:Skeletal class Ⅱ group was consisted of 93 patients, 41 male (aged 18-40 years) and 52 female (aged 22-35 years), with the A point-nasion-B point angle>5°. Class Ⅰ group was consisted of 45 patients, 31 female (aged 20-36 years) and 14 male (aged 17-38 years), with the 1°

ObjectiveThis paper aims to make a research over clinical meaning of VMC with PVB and HRV.Methods22 kids who suffer from VMC with PVB and 28 kids who suffer from HRV and to compare and research their Heart Rate Variability within 24 hours.ResultsThe HRV of the VMC with PVB sufferers had decreased apparently within 24 hours( with discrepancy P ＜0.01 ).ConclusionThere exists apparent DIND in the VMC with PVB sufferers.HRV could be used to check the severness of the disease and prognosis.

Objective To compare the effects of hyperbaric oxygenation(HBO) and routine therapy on diabetic foot. Methods Thirty six subjects were randomized to HBO and routine groups. In HBO group,patients stayed in 0.25 MPa HBO chamber for 100 min,wearing masks and inhaling pure oxygen for 60 min,with 10 min interval.This treatment was performed once a day for 10 times as a course,altogether 2 courses for each patient.By means of hemorrheology and electromyograghy (EMG), and the color Doppler ultrasonograghy of lower extremities for detection of the microcirculation states of lower limbs, thirty six patients with diabetic foot were assessed. Results In HBO group all of patients showed that the abnormalities in hemorrheologic, EMG parameters, and the arteria lesions as revealed by Doppler ultrasonograghy were improved more or less compared with before the treatment( P

Acupuncture Points ; Acupuncture Therapy ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Panic Disorder ; psychology ; therapy ; Treatment Outcome

Objective:To investigate the protein expression levels of breast cancer metastasis suppressor 1 (BRMS1) and Con-nexin 43 (Cx43) in thyroid cancer and their correlation with clinicopathologic parameters. Methods:Immunohistochemistry Streptavi-din-Peroxidase method was used to detect the BRMS1 and Cx43 protein expression in 195 tissue samples, including 90 cases with thy-roid carcinoma, 45 cases with thyroid adenoma, 30 cases with nodular goiter, and 30 cases with normal thyroid glands. Results:The positive rates of BRMS1 and Cx43 expression was 56.7%(51/90) and 41.1%(37/90) in thyroid carcinoma, respectively, which are sig-nificantly lower than the rates in thyroid adenoma, nodular goiter, and normal thyroid gland tissues (P<0.001). Of the three pathological types of thyroid cancer, the positive expression rate of Cx43 was 61.9%in papillary carcinoma, 27.8%in medullary carcinoma, 27.3%in follicular carcinoma, and 12.5%in undifferentiated carcinoma. Statistical differences in the BRMS1 expression among papillary car-cinoma and the other pathological types were also noted. Unlike the patients without lymph node metastasis, the positive expression of BRMS1 and Cx43 proteins were both significantly low among patients suffering from nodal metastasis. Subgroup analysis shows that the positive expression of BRMS1 and Cx43 protein gradually decreased with TNM staging. In addition, a positive correlation was ob-served between the BRMS1 and Cx43 protein expression (r=0.494, P=0.032). Conclusion:The decreased expression of BRMS1 and Cx43 proteins is significantly correlated with the metastasis of thyroid cancer and malignant grade. The combined detection of the two proteins can be ideal biomarkers for judging the prognosis of thyroid carcinoma.

Objective To investigate the rural medical orientation undergraduate student's professional commitment,time management disposition and learning burnout and the relationship between them. Methods Use the college students' learning Burnout scale,adolescence time management disposition Questionnaire and College Students'professional commitment scale,survey of Xinxiang Medical University grade 2010 ~2012,739 valid ques?tionnaires,the questionnaire has 92. 61% efficiency. Results Three scores were normally distribution. Learning burnout was the medium level,the average score of each entry was 2.88±0.45,and moderate and above level learn?ing burnout ratio was 45.06%. The average score of time management disposition was 3.45±0.43. Professional com?mitment level was higher,the average score was 3.82±0.43 for each item. Affective commitment,ideal commitment, the sense of time efficacy and the sense of time control have entered on the learning burnout of the stepwise regres?sion equation,and four variables together explained 44.0% of the variance in the dependent variable. Time manage?ment disposition,the professional commitment and learning burnout were negatively correlated, but between time management disposition and professional commitment is positively related, professional commitment, the variance explained by variables of learning burnout was 30.12%. Conclusion The rural medical orientation of undergradu?ate students time management disposition are important factors of learning burnout,which has the forecast function to the learning burnout. Professional commitment is part of the intermediary variables.

Traditional Chinese medicine exercise therapy has a long history in rehabilitation and keep in good health, which pays attention to integration of body and spirit.There are many clinical studies proving that it can improve heart function and quality of life in patients with cardiovascular diseases, and it is suitable for vigorously generalizing.