Adolescent ; Adult ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Common Cold ; prevention & control ; Female ; Humans ; Male ; Medicine, Chinese Traditional ; Middle Aged

Acute cerebral infarction needs a fast and effective imaging examination to help determine the diagnosis,analyze the causes,guide the treatment,and determine the prognosis.Multimodal CT examination obtains a wide range of reformation in a single scan,including anatomy,hemodynamics and etiology,and provides objective imaging evidence for comprehensive evaluation and appropriate treatment of cerebral infarction.This article reviews the application of this technology in acute cerebral infarction.

OBJECTIVE: To establish the quality standard of Guanxinjing capsule. METHODS:Ligusticum chuanxiong, Borneolum Syntheticum, Radix Paeoniae Rubra, Panax ginseng and Panax notogiseng were identified qualititively by TLC. The content of Protocatechuic aldehyde in salvia miltiorrhiza was determined by HPLC. RESULTS: The TLC spots were distinct and well-separated. The average recovery of the added sample was 99.91% and RSD was 1.56%. CONCLUSION: The established standard is suitable for the quality control of Guanxinjing capsule.

Congenital heart disease and airway anomalies are correlated,and some special cardiovascular anomalies accompanying with airway anomalies like vascular tings,have a high morbidity.Congenital heart disease with airway anomalies is usually ignored in clinic.It should be considered that congenital heart disease with airway anomalies exists in children with the symptoms,such as repeated stridor,respiratory failure,difficult intubation or failure of postoperative ventilator weaning.Multidetector helical CT and bronchoscopy are important for making early diagnosis and guiding management for congenital heart disease with airway anomalies.The choice of therapeutic approaches depends on the type of airway anomalies,location and degree of the lesion.

OBJECTIVE:To optimize the coating technology of modified release film of budesonide colonic localization tablet. METHODS: The effect of the coating parameters such as spray gun position, spraying rate, spraying atomization pressure, intake air temperature and flow, temperature of tablet bed on the microporous semipermeable film and the enteric film of localization tablet were investigated, respectively. RESULTS: The distance between spray gun muzzle and tablet bed was established as 10～20 cm; the spraying rates of the microporous semipermeable film and the enteric film of localization tablet were 3 and 1 mL?min-1, respectively, with their spraying atomization pressure at 2 and 1.5 bar(1 bar=105 Pa), intake air temperature at 50～55 ℃ and 40～45 ℃, temperature of tablet bed at (40?1) ℃ and (30?1) ℃, flow rate of intake air at 5 and 7 m3?min-1 respectively. The weight of the optimized localization tablet after being coated with semipermeable film and enteric film increased by 10% and 5%, respectively. The cumulative drug release within 24 h reached (77.5?8.6)% and the lag time was (6.0?0.5) h. CONCLUSIONS: The optimized coating technology is suitable for the preparation of modified film of budesonide colonic localization tablet.

PBL and CTM integration method is a kind of heuristic education mode of regarding student as the center of education.In order to explore the application result of this teaching method in the curriculum of nursing ethics laws and regulations,we put this mode into practice and regard nursing students as research objects.Questionnaire investigation and paper test are applied to evaluate the teaching effect.The study result shows that PBL and CTM integration method is certainly a well-established method to enhance teaching quality in the curriculum of nursing ethics laws and regulations.

Objective To analyze clinical features of papillary thyroid microcarcinoma(PTMC) and to evaluate the diagnosis and treatment for PTMC.Methods The clinical data of 447 cases of PTMC receiving surgical treatment and confirmed by pathology were reviewed.Color Doppler ultrasonography was used to identify thyroid nodules and cervical lymph nodes,and frozen section was used to confirm the pathological diagnosis during operation.104 cases received unilateral lobectomy,22 cases received unilateral lobectomy plus isthmectomy,321 cases received total thyroidectomy,257 cases underwent central neck dissection,and 54 cases underwent lateral neck dissection(level Ⅵ included).All cases took levothyroxine to maintain low TSH level after operation,and were followed up through telephone or in out-patient clinic.Results Central compartment node metastasis was found in 144 patients,and lateral neck metastasis was found in 41 cN1 cases.The age,extra-capsular invasion and multifocal carcinoma were independent risk factors of PTMC.The number of positive nodes in level Ⅵ was positively correlated with the risk of lateral node metastasis.395 cases were followed-up successfully for 20 to 42 months,with the media follow-up of 32 months.During the follow-up,recurrence or metastasis was found in 15 cases,and no death happened.Conclusions PTMC has no specific symptoms,and was difficult to be diagnosed before operation.Physical examination and color Doppler ultrasonography should be used as routine examination.Thyroid lobectomy and total thyroidectomy plus central node dissection should be major surgical treatment for PTMC patients.Lateral neck dissection should be considered in all cN1 patients.

Objective To investigate the methods for the detection of serum samples with low-concentration HBsAg and its clin-ical value.Methods Serum samples with HBsAg weak positive were measured by ELISA or using Roch cobas e601 were collected from the clinical laboratory.The samples with low-concentration HBsAg were confirmed by neutralization assay by using Lizhu ELISA reagent Kit or Roch cobas e601 analyzer.at the same time,ALT/AST concentrations and HBV DNA copies were also deter-mined.Results Among 53 samples that showed weak positive reaction by using Kehua reagent kit,37 samples were positive in neu-tralization test,while the other 16 samples were negative.Among 18 samples that showed weak positive reaction tested by using Roch cobas e601 analyzer,13 samples showed positive in neutralization test,and the other 5 samples showed negative.Conclusion The results of HBsAg test varies in different detection System.The clinical significance of samples with low-concentration HBsAg needs further study.

Objective:To evaluate the utilization of oral hypoglycemic drugs in 34 hospitals of Nanjing to provide clinical reference for the drug rational use. Methods: According to the sales data of oral hypoglycemic drugs in 34 hospitals of Nanjing from 2011 to 2013,the utilization of oral hypoglycemic drugs was analyzed retrospectively in respect of consumption sum,DDDs and defined daily cost ( DDC) by daily dose limit analysis method. Results: The top 3 oral hypoglycemic drugs in the list of consumption sum were acarbose,glimepiride and metformin. In terms of DDDs,glimepiride, metformin and gliclazide ranked the top 3. The consumption sum and DDDs of oral hypoglycemic drugs were increased year by year in Nanjing. The ratio of serial number of consumption sum and DDDs was from 0. 3 to 2. 0. Conclusion: The demanded quantity of oral hypoglycemic drugs is increased year by year from 2011 to 2013. The application conforms to the safe, effective and economic principle. The drugs should be chosen according to the drug characteristics in order to improve the abnormal glucose metabolism and prevent and treat the complications.

Phase-contrast magnetic resonance imaging (PC-MRI) is a valuable and noninvasive method for evaluating hemodynamics and assessing the severity of disease processes involving the cardiovascular system. The basical principles, influential factors and the applications of PC-MRI in the assessment of cardiovascular diseases were reviewed in this paper.