This article introduces a multiplying channel pulse tracings detection system based on the three-part theory of pulse examination in traditional Chinese medicine which can be applied in experimental animals.Managed multiplex transducer spikes were transmitted to the computer by USB,then matched with per se developmental data analysis and processings of tware,could get the pressure sphygmogram,one circuitry standard electrocardio-signal and one circuitry photoelectricity cubage sphygmogram in the three different parts.It has good effect though by primary animal experiments.

The structure and characteristics of the soluble exopolysaccharide(PS-238) produced by Alcaligenes sp.NX-3 were studied.The analytic sample was prepared by ethanol precipitation then proteins were removed by the Sevag method.The components of polysaccharide were identified by TLC、 GC and chemical method after acid hydrolysis as: glucose,mannose,rhamnose and glucuronic acid.By means of IR and periodate oxidation,it showed that the polysaccharide was mainly consisting of(1→3)and(1→4) glucosidic linkages.The relation between viscosity and shear rate、concentration、temperature、pH and salts was investigated.The results showed that the solution of PS-238 is a typical pseudoplastic liquid,having high viscosity at low concentrations.The viscosity of 1%PS-238 water solution could reach 3300cp at 25℃.It has the excellent stability towards pH2~13,also has outstanding property of viscosity retention even at temperatures up to 150℃.Some kinds of salts were cooperated with PS-238 as a thickening agent.

Objective To explore the molecular targets and mechanisms that could influence the sensitivity of triple negative breast cancer (TNBC) to chemotherapy,to provide important references for the chemotherapy based on gene detection.Methods The gene expression dataset GSE43502 was downloaded from the Gene Expression Omnibus in National Center for Biotechnology Information (NCBI).Gene expression data preprocessing was conducted by R Programming.The differentially expressed genes in the TNBC patients that relapsed after chemotherapy compared with the non-relapsed ones were obtained.Besides,the Database for Annotation Visualization and Integrated analysis (DAVID) was used for functional analysis of those genes.The microRNA (miRNA) that might regulate the differentially expressed genes was obtained from the starBase database.Furthermore,Cytoscape was used for the construction of miRNA-gene regulation network.Results Three hundred and twelve differentially expressed genes were obtained.Some biological process related to cell membrane,metal ion homeostasis and pathways involved in immune and inflammatory were found to be enriched in those genes.Furthermore,171 miRNA that might regulate the differentially expressed genes were obtained and 553 miRNA-gene regulation pairs were formed.Conclusions hsa-miR-30d-5p,SIX4,etc.might influence the sensitivity of TNBC to chemotherapy through cell structure or immune system.

Objective To design and develop a quadrature demodulation circuit for detection of ampli-tude and phase information in EIT measurement. Methods A model structure file was built in matlab/simulink using the elements in Ahera DSP Builder and verified by simulated stimulation. Then the model file was convert-ed to VHDL file via Signal Compiler, and the synthesis, adaptation, simulation and hardware implementation were accomplished. Results The simulation and testing results show that the circuit can extract the real and imagi-nary information of the measured signal and it also meets the EIT measuring requirement, with acceptable mea-sure error. Conclusion The demodulation circuit based on DSP Builder can precisely give real and imaginary information of EIT and provides technological support for full-information complex impedance measurement.

Objective To develop a new,three dimensional dynamic system for pulse detection.Methods According to bionics,a multi-information sensing mode with a soft surface is designed on the basis of traditional Chinese medical diagnosis in pulse.This mode imitates the touching sense of human finger and with the application of modern computer information processing technique,the pulse information is extracted in the way that is as close as possible to the traditional Chinese medicine pulse diagnosis.Results With the application of new sensor,pulse signal is detected and the effectiveness of the inovative three-dimension data transimition mode is validated since the pulse signal is three-dimensionally re-displayed on the computer screen.Conclusion The method introduced in this paper is proved feasible for detecting pulse information.Expected results are obtained and the method provides a new way and new feature reference for research and teaching in objectifying the diagnosis of traditional Chinese medical sciences.

The malignant tumor of bone and soft tissue is conventional rays(X,γrays)resistant. The heavy ion rays 12C+ have following characteristics: high linear energy transfer, Bragg peak, small scattering, high biological effect, lethal damage to tumor cell, and double-strand break to the DNA. Therefore, heavy ion rays Call allow tumor target area obtain high radiation doses while surrounding normal tissues get best protection Recent progress of basic and clinical research on heavy ion treating malignant tumor of bone and soft tissue is discussed.

Objective The Hilbert- Huang transformation (HHT) method was introduced to process the bio-impedance gastric motility signals from subjects.Methods Nonlinear and non-stationary original gastric motility series were decomposed into a number of intrinsic mode function (1MF) components by the empirical mode decomposition method (EMD).Hilbert transformation was carried out then and instantaneous frequency was extracted effectively.Gastric motility signal among 0.03-0.06 Hz was reconstructed from the IMF.Results The results suggested that HHT was a new and applicable time series analysis method based on mode decomposition and could extract impedance signal and remove the disturbances such as blood flow and breathing.Conclusion The new adaptive mode decomposition-based signal processing method provides a new method to investigate clinical gastric motility information.

Objective To evaluate the feasibility,safety and outcome of laparoscopic total mesorectal excision with sphincter preservation in the treatment of low rectal cancer.Methods From April 2004 to April 2007,laparoscopic total mesorectal excision with sphincter preservation for low rectal carcinoma was performed in 25 cases.The intraoperative risk.recovery,short-term and oncological outcomes of these patients were compared with 25 cases of conventional Dixon's operation.The controls,matched for age,sex,mass margin distance from the anus,Dukes stage,were selected from conventional Dixon's operations performed at the same period as laparoscopic group.T test and Chi-square test were used.Results Laparoscopic procedure was successful in 24 cases while one was converted to Bacon operation.The mean operation time(197±36)min in laparoscopic group was significantly longer than those(172±51)min in open group(t=2.12,P=0.04).The mean operative blood loss was(157±105)ml in laparoscopic group and(304±237)ml in open group(t=-2.95,P=0.01).No significant differences were detected between two groups in specimen length and number of lymph nodes excised.The bowel function was restored earlier in laparoseopic group than that in open group.The overall morbidity rates were 16%and 28%,and the local recurrence rates were 8%and 4%in the two groups respectively.Conclusion Laparoscopic total mesorectal excision is a feasible,safe,minimally invasive technique for rectal cancer.which provides better short-term outcomes and similar oncological outcomes compared with the traditional open procedure.

Objective To develop one kind of mainstream ET-CO2 (carbon dioxide of the expiration tip)detector which provides accurate and real-time testing results. Methods Applying ADμC7026 as central processing unit for data pre-processing, temperature compensation algorithm and non-linear correction, the ETCO2 concentration, respiration waveform and respiration rate were obtained. Results The analyzing results of the experimental data shows that the system meets the design requirements with fine stability, rapid response, good repeatability and high accuracy. Conclusion ET-CO2 detector based on ADμC7026 makes the detection of CO2 more accurate and reliable, which provides more accurate real-time data for critical patient monitoring, anesthetic care, pediatric respiratory care and so on.

Objective To observe therapeutic effects of treating stroke hemiplegia with acupuncture combined with rehabilitation training. Methods 72 patients with stroke hemiplegia were randomly recruited into a control group and a treatment group, with 36 patients in each group. The treatment group was treated with acupuncture combined with rehabilitation training and the control group was treated with acupuncture exclusively. Both scalp acupuncture and body acupuncture were used in the process of treatment. Results There was statistical significance (P<0.01) between the two groups in functional rehabilitation of limbs and ADL score (P<0.01) . Conclusion The treatment of stroke hemiplegia with acupuncture combined with rehabilitation training is more effective than that of treating with acupuncture exclusively.