28 lots of HB vaccine, produced from 1997 to 1999, have been tested for sterility, safety, potency and pyrogenicity. All of the 28 lots meet the WHO's requirements for human plasma-derived hepatitis B vaccine
Hepatitis B Vaccines ; Vaccines

No abstract available.
Hepatitis B Vaccines* ; Hepatitis B* ; Hepatitis* ; Humans

Antibody efficacy was investigated on 98 children after hepatitis B vaccination at time of 30 months after the first dose in HuÕ City. It was found that only 30.6% of children who were vaccinated in 1998 have antibody response at protectable level. 100% of those have low-level antibody response. Cause of poor antibody response can be the duration between the first and the third doses is short. 100% of children were injected vaccine at the delta muscle, instead of the lateral-anterior thigh.
Hepatitis B Vaccines ; child

110 seaman in Hai Phong were infected Engerise B vaccine Good immune response through antibody responsivity effect was reached. For the first injectiong, the responsivity in 72,73% of cases, GMT altained to 135,5 mIU/ml; for the 2nd and the 3 rd injections, the respective values were 81,82%, 94,55% and 327,2 mIU/ml, 680,5 mIU/ml, with p>0,05 and p< 0,001. Topic and systemic side effect rates were very low.
Hepatitis B Vaccines ; Viral Hepatitis Vaccines ; Male

2 reduced doses of plasma-derived hepatitis B vaccine produced by the National Institute of Hygiene an Epidemiology (NIHE): 2.5g (VN2,5) and 5g (VN5) was compared with 2 pediatric standard doses (10g) of recombinant vaccine from 2 Korean companies. The vaccines were administrated intramuscularly in 700 neonates at months 0, 1, 2 with postvaccineation serology tested at month 8. The seroconversion rate of 2 reduced doses are comparable with 2 control groups. Geometric mean titer of low-risk newborns in group VN2,5 were similar to group VN5, but significantly lower than control groups.
Hepatitis B ; Infant, Newborn ; Hepatitis B Vaccines

A study on immunogenicity of hepatitis B vaccine produced by NIHE, Hanoi was conducted on 240 children under 1 year old in Nha Trang during 1994-1996. The vaccination schedule was 0, 1, 6 month. Blood sampling was performed at 3, 7, 12 month after vaccination. All children were given 10g/dose. The immunogenicity was following: seroconvertion rates were 82.89%, 96.97% and 97.97% with GMT: 120.69, 473.38 and 258.2 UI/L, respectively. The antibody response rates were the same in 2 groups, but GMT of newborn was higher than on children of 6-12 months old and there was a statistical significant difference.
Immunization ; hepatitis B vaccines ; child

Hepatitis B Vaccines ; Humans ; Vaccination

No abstract available.
Hepatitis B Vaccines* ; Hepatitis B* ; Hepatitis* ; Humans ; Infant*

No abstract available.
DNA, Recombinant* ; Hepatitis B Vaccines* ; Hepatitis B* ; Hepatitis* ; Yeasts*

No abstract available.
Alleles* ; Hepatitis B Vaccines* ; Hepatitis B* ; Hepatitis* ; HLA-DRB1 Chains*