Ehlers-Danlos syndrome type IV(the arterial-ecchymotic type) which has skin fragility, easy bruisability, and j oint hyperextensibility is occasionally combined with large vessel involve-ment and spontaneous catastrophic bleeding. As even a small inj ury can cause profound vascular tearing and damage, surgical management is hazardous and often unrewarding. We report a successful surgical treatment of an acute type A aortic dissection associated with Ehlers-Danlos syndrome.
Ehlers-Danlos Syndrome* ; Hemorrhage ; Skin

This study included 55 patients who admitted to Huu Nghi Hospital from 1985 to 1998. It is found that spleen enlargement is common in myeloproliferative conditions, with the incidence is 100% of patients who have chronic granulocytic leukemia and those have idiopathic myelosclerosis. These patients have grade II or more of spleen enlargement. This symptom is less common in patients who have polycythemia vera or essential trombocythemia, and these patients are likely to have grade I of spleen enlargement. Anemia is more likely to be found in patients with chronic granulocytic leukemia, especially in those with idiopathic myelosclerosis, but this symptom is infrequent in patients with essential trombocythemia. Patients with polycythemia vera in typical have excessive blood. Infection and hemorrhage occurred predominantly in patients with chronic granulocytic leukemia and in some cases of essential trombocythemia. Symptoms of high blood pressure, tip finger bruise and limb weakness have been found mainly in patients with polycythemia vera. In some cases with polycythemia vera, both red cell and white cell counts are increased. While patients with chronic granulocytic leukemia, polycythemia vera and idiopathic myelosclerosis expresses obvious clinical symptoms, the symptoms in patients who have essential trombocythemia are unmarked.
Myeloproliferative Disorders ; Hemorrhage ; diagnosis ; syndrome

No abstract available.
Arteriovenous Malformations* ; Gerstmann Syndrome* ; Hemorrhage* ; Rabeprazole*

Behcet Syndrome ; complications ; Hemorrhage ; etiology ; Humans ; Pharynx

The HELLP syndrome, which is characterized by hemolysis, elevated liver enzymes and low platelets, complicates 4 to 14% of preeclamptic or eclamptic pregnancy. Its course is usually benign except when spontaneous hepatic rupture, a rare catastrophic event, threatens life. The authors have experienced one case of spontaneous hepatic rupture in HELLP syndrome during immediate postpartum period, which was treated with surgical intervention on the first postpartum day. We report this case with a brief review of the literatures.
Female ; HELLP Syndrome* ; Hemolysis ; Hemorrhage* ; Liver ; Postpartum Period* ; Pregnancy ; Rupture*

The main treatment for Antiphospholipid syndrome (APS) is long-term anticoagulation with an oral vitamin K antagonist, although these are associated with numerous problems. Rivaroxaban is a direct anti-factor Xa inhibitor, with a predictable anticoagulant effect at fixed doses. There are limited reports of rivaroxaban use in APS. We present four cases of patients with APS who received rivaroxaban treatment for six months without thrombosis recurrence or bleeding. Three of the patients received rivaroxaban as initial therapy. In the systematic review, only five patients were treated with rivaroxaban as a thromboprophylaxis. Of the 71 cases of rivaroxaban use including our study, there were seven cases (9.9%) of thrombosis recurrence and two reports of bleeding. The efficacy of rivaroxaban in APS patients was at least equal to warfarin therapy. This report and systematic review suggest that rivaroxaban can be considered cautiously as a thromboprophylactic or alternative therapy for warfarin in patients with APS.
Antiphospholipid Syndrome* ; Hemorrhage ; Humans ; Recurrence ; Rivaroxaban* ; Thrombosis ; Vitamin K ; Warfarin

Hypereosinophilic syndrome (HES) has three defining features: marked hypereosinophilia for at least 6 months, no confirmed etiology for the eosinophilia, and eosinophilia-related symptoms or organ dysfunction. However, a shorter period of hypereosinophilia with symptoms requiring eosinophil-lowering therapy is also acceptable. We report a case of HES presenting as eosinophilic colitis. Although hypereosinophilia was present for 3 months, this patient needed to be treated with eosionphil-lowering therapy for severe hematochezia. After systemic corticosteroid therapy, symptoms caused by organ involvement were dramatically improved.
Colitis ; Colon ; Eosinophilia ; Eosinophils ; Gastrointestinal Hemorrhage ; Humans ; Hypereosinophilic Syndrome ; Steroids

Peutz-Jeghers syndrome is a genetic disorder consisting of mucocutaneous pigmentation and gastrointestinal polyposis. Although the polyp may be found in a solitary fashion in this syndrome, such a case is exceedingly rare and would result in a case report even in other countries. A solitary Peutz-Jeghers polyp had not been reported domestically until now, and thereby, the authors here present a case of a clinical experience of Peutz-Jeghers syndrome with a solitary hamartomatous polyp in the duodenum.
Diagnosis* ; Duodenum* ; Hemorrhage* ; Peutz-Jeghers Syndrome ; Pigmentation ; Polyps*

Peutz-Jeghers syndrome is a rare autosomal dominant disorder defined by hamartomatous polyps of gastrointestinal tracts and the occurrence of melanin spots on the mucocutaneous surface. This syndrome has important complications such as malignant transformation, gastrointestinal bleeding, and intussusception. About 50% of patients with Peutz-Jeghers syndrome involved Intussusception. A case of Peutz-Jeghers syndrome with intussusception was recently experienced and herein reported.
Gastrointestinal Tract ; Hemorrhage ; Humans ; Intussusception* ; Melanins ; Peutz-Jeghers Syndrome* ; Polyps

Aneurysm, Dissecting ; Aortic Aneurysm ; Cerebral Hemorrhage ; Humans ; Myocardial Infarction ; Syndrome