Kawasaki disease (KD) is one of the most common causes of acquired heart disase in children,the development of which is closely related to the allergic diseases.Recent studies have manifested that the incidence of allergic diseases in children with KD is far higher than that in those children without KD.Meanwhile,the morbidity of KD in allergic children is significantly higher than that in those who do not have family medical history of allergic diseases.By far,the mechanisms causing interaction between KD and allergic diseases still remain unclear.Possible mechanisms include IgE-meditated immune response,release of large quantity of cytokines and inflammatory meditators as well as atopic family history.

Kawasaki disease(KD) is the most common reason for acquired heart disease in children,which is closely related to autoimmune response and the release of cytokines in vascular endothelial cells.Steroids are strongly effective in countering inflammation as well as immune response.In the time of being,it has become a hot spot that steroids play an important role in the initial treatment for acute KD and for incomplete and refractory KD.

Belief in and rejection of a relationship of occlusion and temporomandibular joint (TMJ)condyle-fossa position with normal and abnormal function are still contentious issues.Clinical opinions can be strong,but support in most published data (mostly univariate)is problematic.Distribution overlap,low sensitivity and specificity are a common basis to reject any useful prediction value.Notwithstanding,a relationship of form with function is a basic tenet of biology.These are multifactor problems,but the questions mostly have not been analysed as such.This review moves the question forward by focusing on TMjoint anatomic organisation as the multifactor system it is expected to be in a closed system like a synovial joint.Multifactor analysis allows the data to speak for itself and reduces bias.Classification tree analysis revealed useful prediction values and usable clinical models which are illustrated,backed up by stepwise logistic regression.Explained vari-ance,R2 ,predicting normals from pooled TMJ patients was 32.6%,sensitivity 67.9%,specificity 85.7%;37% versus disc displacement with reduction;and 28.8% versus disc displacement without reduction.Significant osseous organisational differences between TMjoints with clicking and locking suggest that this is not necessarily a single disease continuum.However,a subset of joints with clicking contained char-acteristics of joints with locking that might contribute to symptom progression versus resistance.Moderately strong models confirm there is a relationship between TMJ osseous organisation and function,but it should not be overstated.More than one model of normals and of TMde-rangement organisation is revealed.The implications to clinical decision-making are discussed.

COX-2 is the inducible form of cyclooxygenase,which is overexpressed in non-small cell lung cancer,especially in the adenocarcinoma,and is involved in the production of lung cancer drug resistance, reducing the sensitivities of tumor cells to chemotherapy drugs. COX-2 inhibitors have the effects of antitumor and prevention of tumor formation. Therefore,in order to reverse the drug resistance of tumor cells,improve the sur-vival rate and the prognosis of patients with tumor,the application of COX-2 inhibitors as adjuvant chemotherapy and combined with chemotherapy drugs has become a new direction in the treatment of lung cancer.

Currently our medical colleges have no uniform competency standards for teachers teaching,and the assessment of teaching ability is vaguely defined.Through the content and effect analysis of foreign teaching competency standards assessment,according to the particularity of medical colleges,and by carding several aspects of the teacher ability content system,the author of the article put forward recommendations of building our medical colleges teacher teaching competency standards and improve medical colleges teachers' teaching ability and level.

Objective To observe the therapeutic effects and toxicities of bone marrow-sparing intensity-modulated radiation therapy (BMS-IMRT) for postoperative cervical cancer.Methods From January 2011 to June 2012,totally 70 postoperative patients with cervical cancer were divided into BMS-IMRT group with 34 cases and IMRT group with 36 cases randomly.External whole pelvic intensitymodulated irradiation combined with chemotherapy was carried out for all patients.The planning target volume received a dose of 45 Gy/25 fractions in all patients.Delineation of the pelvis and limitation dose were carried out in BMS-IMRT group:the pelvis V30 ≤ 50％.All cases received chemotherapy with cisplatin (40 mg/m2) once a week concurrently with radiotherapy.Results Treatment was completed in 67 patients,as the other 3 patients stopped chemotherapy because of myelosuppression.There was no statistically significant differences between two groups for the 2-year local control survival(LCS)and overall survival(OS),alimentary tract toxicity and urinary toxicity.IMRT group had more serious hematologic toxicity than BMS-IMRT group,with statistically significant difference (x2 =14.355,P ＜ 0.05).Conclusions The postoperative cervical cancer patients with poor prognostic factors who undergo concurrent chemoradiotherapy,IMRT group has more serious hematologic toxicity than BMS-IMRT group.The short-term effect and other toxicities reaction are similar between two groups.

ObjectivesTo study the current status of child neglect and its inlfuencing factors in children aged 3-6 years in rural Henan.MethodsScales and evaluation methods in the Chinese rural child aged 3-6 years neglected eval-uation model were applied in this study. The neglect rate and the neglect degree were used to describe the neglect status of rural children aged 3-6 years in Henan. The inlfuencing factors for child neglect were also analyzed. ResultsThe total neglect rate in 450 enrolled children was 37.1% (167/450). The total neglect degree was 51.9±6.5. The boys had signiifcant-ly higher neglect rate than girls (P<0.05). There was no significant difference in neglect degree between boys and girls (P>0.05). There were significant differences in neglect rate and neglect degree among the different age groups (P<0.05), the higher neglect rate and higher neglect degree over age. The neglect rate and neglect degree in nuclear families and fam-ilies with three generations were lower than those in single-parent families and remarried families (P<0.05). The neglect rate and neglect degree in non-only children were higher than those in only children (P<0.05). The left-behind children had signiifcantly higher neglect rate and neglect degree than children living with parents (P<0.05). Based on multivariate logis-tic regression analysis, the risk factors of child neglect were single-parent families (OR = 4.78, 95%CI : 2.10-10.87) and remarried families (OR=4.53, 95%CI : 1.99-10.01). The protective factors of child neglect were parents working on sci-ence (OR = 0.20, 95%CI : 0.10-0.67) and living with parents (OR = 0.03, 95%CI : 0.00-0.54).ConclusionsThe neglect status is serious in Henan rural children, particularly in left-behind children.

A semantic predication network was developed by processing the documents on schizophrenia into se-mantic predication sets using SemRep, from which the core information was extracted to produce a graphic summary which was consisted of highly cohesive cliques.The automatic methods for summarizing biomedical documents were studied using the network properties combined with semantic information.The subthemes in the summary obtained by clustering were evaluated according to the clique co-node matrix and the contents of the summary were assessed according to the reference criteria.The accuracy was 0.93, the recall was 0.68, and the F-value was 0.79 for the summary, indicating that this method can effectively recognize the core information in documents and the semantic information in network graphics.

Objective: To observe the influence of scalp acupuncture plus point injection on intelligence quotient in microcephaly children. Methods: Twenty-five children with microcephaly were treated by scalp acupuncture as main therapy plus point injection. The children's intelligence was tested by China-Wechsler's intelligence scale before and after treatment. Results and Conclusion: Acupuncture can improve intelligence and especially has significant effect on verbal intelligence quotient in microcephaly children.

Hepatitis B virus (HBV)-induced liver failure is a severe clinical syndrome with complicated manifestations resulting in high mortality.The prognosis largely depends on early diagnosis and timely intervention.This article reviews the predictive and prognostic evalua-tion system for the development and progression of HBV-induced liver failure,so to improve the early diagnosis of this disease and the prog-nosis of patients.