1.Gene expression of surfactant-associated proteins.
Tuberculosis and Respiratory Diseases 1991;38(3):228-235
No abstract available.
Gene Expression*
2.TGFbeta1 Effect on Survival of Anticancer Drug - resistant L1210 Sublines.
Sung Yong KIM ; Kyung Sub LEE ; Jae Ryong KIM ; Jeong Hee KIM
Journal of the Korean Cancer Association 1998;30(5):1005-1013
PURPOSE: The inhibitory effect of TGFbeta1 on survivals of L1210 and anticancer drug- resistant L1210 sublines was investigated and the gene expression of TGFbeta1 in these cells was examined. MATERIALS AND METHODS: The survivals of L1210, adriamycin-resistant(L1210AdR), vincristine-resistant(L1210VcR) or cisplatin-resistant(L1210Cis) cells were measured by MTT assay after treatment of TGFbeta1. Northern analysis was performed for TGFbeta1 gene expression in L1210, L1210AdR, L1210VcR or L1210Cis. RESULTS: There was no different survival ratio between two groups, control and TGFbeta1(10 ng/ml) treated groups in L1210 cells. However, the survival ratio of L1210AdR was 59% in TGFbeta1 treated group for 96 hours. The survival ratio of L1210VcR was 61% for 96 hours in TGFbeta1 treated group. The survival ratio of L1210Cis was 40% for 96 hours in TGFbeta1 treated group. Expressions of TGFbeta1 gene in drug-resistant sublines were significantly decreased than that of L1210 cells. CONCLUSION: Growth of anticancer drug-resistant L1210 sublines were inhibited by TGFbeta1 but not in L1210 cells. So, it is suggested that TGFbeta1 gene expression may have a part in anticancer drug-resistance.
Control Groups
;
Gene Expression
3.Regulation of Proenkephalin Gene Expression in Glial Cells.
Journal of Korean Society of Endocrinology 2000;15(6):750-759
No Abstract Available.
Gene Expression*
;
Neuroglia*
4.MDRI gene expression in gastric and colorectal cancer tissues.
Han Kwang YANG ; Jae Gahb PARK ; Jin Pok KIM ; Lori GOLDSTEIN
Journal of the Korean Cancer Association 1991;23(1):54-64
No abstract available.
Colorectal Neoplasms*
;
Gene Expression*
5.In vivo characterization of virulence associated gene expression: II. plasmid-encoded aerobactin production and transferableantimicrobial resistance in E. coli.
Sang Hwa LEE ; Yoo Chul LEE ; Sung Yong SEOL ; Dong Taek CHO
Journal of the Korean Society for Microbiology 1991;26(5):463-477
No abstract available.
Gene Expression*
;
Virulence*
6.Response: Regulating Hypothalamus Gene Expression in Food Intake: Dietary Composition or Calorie Density? (Diabetes Metab J 2017;41:121-7).
Mi JANG ; So Young PARK ; Yong Woon KIM ; Seung Pil JUNG ; Jong Yeon KIM
Diabetes & Metabolism Journal 2017;41(3):225-227
No abstract available.
Eating*
;
Gene Expression*
;
Hypothalamus*
8.Primary determination of allele frequencies of D13S317 locus in Vietnamese population
Journal of Medical Research 2003;23(3):81-85
The study of blood samples extracted directly from healthy people, who is Vietnamese and not relative, lives over the country. PCR technique and denaturing polyacrylamid gel electrophoresis were applied for determination of allele frequencies of D13S317. The primary results showed that allele frequencies of D13S317 locus was polymorphic AND, repetitive sequence unit of 4 nito- base which located on the long hand of chromosome No 13. The locus contained 9 alleles, 242-270 bp. The numbers of repeat units in population were 7, 8, 9, 10, 11, 12, 13, 14, 15. The highest frequency at allele No 8, and allele No 7 had not appear in the observed samples.
Population
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Gene Frequency
;
analysis
9.Inactivation of gene by small interference RNA
Journal of Medical Research 2003;21(1):89-93
The role of suppression of small RNA molecules in the management of malignity and viral infection on human was studies and discussed. SiRNA (small interference RNA) suppressing gene expression was described. In the year 2001, Ribopharma AG researchers had first demontrated the function of RNAi in mammal cells. SIRPLEX is appropriate with target gene, for using in the treatment of suppression of pathological gene in various genera, including human.
RNA
;
Genes
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Gene Silencing
10.Detection of Virulent Gene Distribution of Diarrheagenic Escherichia Coli (DEC)
Journal of Medical Research 2008;0(1):50-55
Introduction: There are 5 identified DEC including EAEC, EHEC, EIEC, EPEC and ETEe. Virulent genes (for adherrnee, toxin, antibiotic resistance ...) play important roles in pathogenesis of DEe. Detection of DEC is very important in diagnosis, epidemiology survey and vaccine development. \r\n', u'Objectives: Detection of virulent gene distribution of DEC and non - DEe.\r\n', u'Object and methods: 161 strains of DEC (EAEC, EIEC, EPEC, TEC) and 100 strains of non - DEC were subjected to this study. PCR with specific primers were used to test these genes. \r\n', u'Results: EAEC that accounted for 50% of DEC, was identified and isolated. Aap gene was the highest prevalence in EAEC (96.5%), followed by aggR (79.1 %) and astA (60.5%). 37.2% of the strains harbor all three genes. None of strains had PCR results negative for these 3 genes. ETEC, EPEC and EIEC had aap, and astA gene at the prevalence from 7% to 72.7%. The highest prevalence of aap was seen in EIEC 72.7%), aggR in EIEC (45.5%), and astA in ETEC (50%). 14% of non - DEC had aggR and more than 30% of E. coli had aap and astA gene. \r\n', u'Conclusion: EAEC is prevalent at 50% among Diarreagenic E. coli. Aap is the most prevalent and the most commonly seen among EAEC isolates. The other three genes are at different prevalence. The findings contribute towards the vaccine development against diarrhea caused by E. coli. \r\n', u'
Distribution
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Virulent gene
;
E.coli
Result Analysis
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