No abstract available.
Gene Expression*

Most statistical methods for finding interesting genes are focusing on the summary values with large fold-changes or large variations. Very few methods consider the probe level data. We developed a new measure to detect reliability that incorporates the probe level data. This reliability measure is useful for exploring the microarray data without ignoring the probe level data. It is easy to calculate, and it can be used for all the other statistical methods as a good guideline to find real differentially expressed genes. Instead of filtering out genes before the analysis, we use whole genes in the analysis and make decisions with new reliability measures.
Gene Expression ; Quality Control

No abstract available.
Eating* ; Gene Expression* ; Hypothalamus*

No abstract available.
Eating* ; Gene Expression* ; Hypothalamus*

No abstract available.
Colorectal Neoplasms* ; Gene Expression*

PURPOSE: The inhibitory effect of TGFbeta1 on survivals of L1210 and anticancer drug- resistant L1210 sublines was investigated and the gene expression of TGFbeta1 in these cells was examined. MATERIALS AND METHODS: The survivals of L1210, adriamycin-resistant(L1210AdR), vincristine-resistant(L1210VcR) or cisplatin-resistant(L1210Cis) cells were measured by MTT assay after treatment of TGFbeta1. Northern analysis was performed for TGFbeta1 gene expression in L1210, L1210AdR, L1210VcR or L1210Cis. RESULTS: There was no different survival ratio between two groups, control and TGFbeta1(10 ng/ml) treated groups in L1210 cells. However, the survival ratio of L1210AdR was 59% in TGFbeta1 treated group for 96 hours. The survival ratio of L1210VcR was 61% for 96 hours in TGFbeta1 treated group. The survival ratio of L1210Cis was 40% for 96 hours in TGFbeta1 treated group. Expressions of TGFbeta1 gene in drug-resistant sublines were significantly decreased than that of L1210 cells. CONCLUSION: Growth of anticancer drug-resistant L1210 sublines were inhibited by TGFbeta1 but not in L1210 cells. So, it is suggested that TGFbeta1 gene expression may have a part in anticancer drug-resistance.
Control Groups ; Gene Expression

No Abstract Available.
Gene Expression* ; Neuroglia*

No abstract available.
Gene Expression* ; Virulence*

The study of blood samples extracted directly from healthy people, who is Vietnamese and not relative, lives over the country. PCR technique and denaturing polyacrylamid gel electrophoresis were applied for determination of allele frequencies of D13S317. The primary results showed that allele frequencies of D13S317 locus was polymorphic AND, repetitive sequence unit of 4 nito- base which located on the long hand of chromosome No 13. The locus contained 9 alleles, 242-270 bp. The numbers of repeat units in population were 7, 8, 9, 10, 11, 12, 13, 14, 15. The highest frequency at allele No 8, and allele No 7 had not appear in the observed samples.
Population ; Gene Frequency ; analysis

The role of suppression of small RNA molecules in the management of malignity and viral infection on human was studies and discussed. SiRNA (small interference RNA) suppressing gene expression was described. In the year 2001, Ribopharma AG researchers had first demontrated the function of RNAi in mammal cells. SIRPLEX is appropriate with target gene, for using in the treatment of suppression of pathological gene in various genera, including human.
RNA ; Genes ; Gene Silencing