1.Analysis of the therapeutic effect of integrated Chinese and Western medicine in treating acute biliogenic pancreatitis after papillary myotomy.
Chinese Journal of Integrated Traditional and Western Medicine 2004;24(2):150-152
Adolescent
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Adult
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Cholecystitis
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complications
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drug therapy
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surgery
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Cholecystolithiasis
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complications
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drug therapy
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surgery
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Drugs, Chinese Herbal
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therapeutic use
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Female
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Humans
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Male
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Middle Aged
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Pancreatitis
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drug therapy
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etiology
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surgery
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Phytotherapy
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Postoperative Period
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Sphincterotomy, Endoscopic
3.Sedative properties of epidural anesthesia
Yi FENG ; Ying SUN ; Deshui YU
Chinese Journal of Anesthesiology 1994;0(05):-
Objective To investigate the potential sedative effects of epidural anesthesia and its mechanism. Methods Fifty ASA Ⅰ -Ⅱ patients aged 20-55yr, scheduled for gynecological surgery were studied. Patients whose body weight exceeded 95 kg or was less than 45kg were excluded. Alcoholics and those addicted to sedative or opiates were also excluded. The patients were unpremedicated. Before anesthesia the patients' radial artery was cannulated for continuous BP monitoring and blood sampling. ECG, BIS and HRV were continuously monitored. Epidural puncture was performed at L1-2 . A catheter was inserted in epidural space for 3-4cm in a cephalad direction. The patients were randomly divided into 3 groups: epidural lidocaine group (group E, n = 15); intravenous lidocaine group (group Ⅰ , n = 15) and control group (group C, n =20). In group E the patients received an iv bolus of lidocaine 1.5mg?kg-1 followed by a lidocaine infusion at a rate of 30mg?kg-1?min-1 and an epidural bolus of normal saline 15 ml; in group C the patients received an epidural bolus of NS 15 ml only. The intravenous lidocaine infusion in group I was designed to mimic systemic absorption of lidocaine from epidural space. 20 min after epidural lidocaine or saline administration, a propofol infusion was started at a rate of 150ml/h until the patients lost consciousness, The amount of propofol infused was recorded. Blood samples were taken before propofol infusion for determination of plasma level of lidocaine. Results The amount of propofol infused when the patients lost consciousness was (1.22 ?0.25) mg?kg-1 in group E, (1.62 ?0.22) mg?kg-1 in group I and (1.85?0.41) mg?kg-1 in control group. The amount of propofol infused in group E was significantly less than that n group I and C ( P
4.Correlation between polymorphism in the promoter of DNA methyltransferase-3B gene and susceptibility of colorectal cancer
International Journal of Biomedical Engineering 2013;36(5):266-269
Objective To observe and analyze the correlation between the DNA methyltransferase-3B (DNMT3B) gene single nucleotide polymorphisms (SNP) rs 1569686 and the susceptibility to colorectal cancer (CRC) in Tianjin Han population.Methods A case-control study was performed.89 CRC patients and 94 normal controls were examined,and Sequenom MassArray system was applied to detect the genotype of rs1569686 in DNMT3B gene polymorphisms.The association results were analyzed of the SNP and CRC.Results The frequencies of genotypes TT,GT and GG at SNP rs1569686 were 74.2%,24.7% and 1.1% in CRC patients respectively,which there were no significant differences from that in controls(73.4%,23.4% and 3.2%; P>0.05).Conclusion It suggests that the SNP rs1569686 of DNMT3B gene may not be related to susceptibility of CRC in Tianjin Han population.
5.Echocardiographic assessment of right heart in normal adults
Li-bin, CHEN ; Feng-ying, YIN ; Sheng-min, ZHANG ; Fei, YU ; Feng, MAO ; You-feng, XU
Chinese Journal of Medical Ultrasound (Electronic Edition) 2013;(9):24-30
Objective To discuss the value of echocardiography for the assessment of structure and function of right heart in normal Chinese adults Methods The structure and function of right heart was assessed by echocardiography according to 2010 guideline of American Society of Echocardiography (ASE). The echocardiographic data of right heart of 130 normal Chinese adults were analyzed to acquire the normal reference values of echocardiographic parameters and evaluate the differences of these results among different age groups. Results There were significant differences among different age groups for some of the parameters. Right atrium (RA) transverse diameter was greater in the middle-aged group than that in the young-aged group [(36.90±5.10) mm vs (33.90±5.20) mm, t=-2.79, P=0.006]. RA longitudinal diameter (RAL) and RA area (RAA) were smaller in the young-aged group than those in the middle-aged and old-aged groups [(40.10±5.10) mm vs (42.90±5.10) mm, (43.40±5.60) mm, t=-2.51 and-2.91, P=0.013 and 0.004;(11.90±3.20) mm2 vs (13.40±2.90) mm2, (13.90±3.60) mm2, t=-2.24 and-2.90, P=0.027 and 0.004]. Parasternal long-axis right ventricule outflow tract (PLAX RVOT), parasternal short-axis right ventricule outflow tract (PSAX RVOT) and pulmonary artery diameter (PAD) were smaller in the young-aged group than those in the middle-aged and old-aged groups [(24.20±3.00) mm vs (26.20±2.30) mm, (25.90±2.90) mm, t=-2.80 and-2.32, P=0.006 and 0.022;(24.70±3.00) mm vs (27.20±2.50) mm, (26.90±2.60) mm, t=-4.40 and -3.84, P=0.000 and 0.000; (20.60±2.00) mm vs (22.10±2.70) mm, (21.90±2.10) mm, t=-3.12 and-2.67, P=0.002 and 0.008]. RV lateral wall thickness was smaller in the young-aged group than that in the middle-aged and old-aged groups [(5.10±0.60) mm vs (5.60±0.60) mm, (5.40±0.70) mm, t=-3.12 and-2.22, P=0.02 and 0.028];DTI e wave was greater in the young-aged group than that in the middle-aged and old-aged groups [(14.90±3.70) cm/s vs (10.90±3.10) cm/s, (11.10±2.60) cm/s, t=5.82 and 5.49, P=0.000 and 0.000]. DTI a wave was smaller in the young-aged group than that in the middle-aged and old-aged groups [(12.50±3.90) cm/s vs (14.60±3.70) cm/s, (16.60±3.60) cm/s, t=-2.79 and -5.04, P=0.007 and 0.000] and DTI a wave was smaller in the middle-aged group than that in the old-aged group (t=-2.26, P=0.02). Tricuspid E wave was greater in the young-aged group than that in the middle-aged and old-aged groups [(0.61±0.11) m/s vs (0.51±0.11) m/s, (0.48±0.08) m/s, t=4.58 and 5.44, P=0.000 and 0.000]. E/A was greater in the young-aged group than that in the middle-aged and old-aged groups (1.45±0.30 vs 1.12±0.33, 1.10±0.27, t=4.58 and 5.44, P=0.000 and 0.000). No significant differences were found among different age groups in RV systolic function parameters, whereas a trend of decrease in RV diastolic function was detected. Conclusion Echocardiography can be useful in assessing the structure and function of right heart quantitatively.
6.A case of Guillain-Barre syndrome complicated with posterior reversible encephalopathy syndrome.
Ying YANG ; Jian-hua FENG ; Yu-wen DAI
Chinese Journal of Pediatrics 2013;51(6):477-478
Biomarkers
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blood
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Brain
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diagnostic imaging
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pathology
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Brain Edema
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etiology
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pathology
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Child
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Diagnosis, Differential
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Electroencephalography
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Guillain-Barre Syndrome
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complications
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diagnosis
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therapy
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Humans
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Magnetic Resonance Imaging
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Male
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Posterior Leukoencephalopathy Syndrome
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complications
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diagnosis
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therapy
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Radiography
8.Primary signet-ring cell-like histiocytic sarcoma arising in stomach: report of a case.
Zhong-yan GUAN ; Yu-fang FENG ; Ying-yong HOU
Chinese Journal of Pathology 2012;41(11):772-773
Aged
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Antigens, CD
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metabolism
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Antigens, Differentiation, Myelomonocytic
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metabolism
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Carcinoma, Signet Ring Cell
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metabolism
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pathology
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surgery
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Diagnosis, Differential
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Gastrectomy
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methods
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Histiocytic Sarcoma
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metabolism
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pathology
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surgery
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Humans
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Lymphatic Metastasis
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Male
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Phosphoglucomutase
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metabolism
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Stomach Neoplasms
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metabolism
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pathology
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surgery
9.Design of a system for real-time seizure detection and closed-loop electrical stimulation.
Zhenhua HU ; Zhouyan FENG ; Xiaojing ZHENG ; Ying YU
Journal of Biomedical Engineering 2015;32(1):168-174
In order to investigate the effect of deep brain stimulation on diseases such as epilepsy, we developed a closed-loop electrical stimulation system using LabVIEW virtual instrument environment and NI data acquisition card. The system was used to detect electrical signals of epileptic seizures automatically and to generate electrical stimuli. We designed a novel automatic detection algorithm of epileptic seizures by combining three features of field potentials: the amplitude, slope and coastline index. Experimental results of rat epileptic model in the hippocampal region showed that the system was able to detect epileptic seizures with an accuracy rate 91.3% and false rate 8.0%. Furthermore, the on-line high frequency electrical stimuli showed a suppression effect on seizures. In addition, the system was adaptive and flexible with multiple work modes, such as automatic and manual modes. Moreover, the simple time-domain algorithm of seizure detection guaranteed the real-time feature of the system and provided an easy-to-use equipment for the experiment researches of epilepsy control by electrical stimulation.
Algorithms
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Animals
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Deep Brain Stimulation
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instrumentation
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Disease Models, Animal
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Electroencephalography
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Epilepsy
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diagnosis
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Equipment Design
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Rats
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Seizures
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diagnosis
10.Efficacy of voriconazole for treatment of invasive fungal infections in 87 cases with hematologic malignancies.
Ai-Mei FENG ; Ju-Ying WEI ; Wen-Juan YU
Chinese Journal of Hematology 2011;32(7):473-475
Adult
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Aged
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Aged, 80 and over
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Antifungal Agents
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therapeutic use
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Female
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Hematologic Neoplasms
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drug therapy
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microbiology
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Humans
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Male
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Middle Aged
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Mycoses
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complications
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drug therapy
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Pyrimidines
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therapeutic use
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Treatment Outcome
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Triazoles
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therapeutic use
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Voriconazole
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Young Adult