PURPOSE: To evaluate the association with corneal thickness and corneal thinnest point using Orbscan topography. METHODS: One hundred and four eyes of the 52 normal subjects who were investigated using an Orbscan topography, were devided into following two groups ; one was inferonasal group which has the thinnest point in inferonasal quadrant(23 eyes, 22.1%), and the other was inferotemporal group which has the thinnest point in inferotemporal quadrant. (79 eyes, 76%) Among them, age-matched 30 eyes were randomly selected. The corneal thickness of two groups were measured at eight meridian of each point distant 1.0, 1.5, 2.0, 2.5, 3.0mm from corneal center. The thickest point and the thinnest point of cornea in two groups were compared and analysed. RESULTS: The thickest point of cornea in two groups was located in the superior portion. The thinnest quadrant was located in the inferonasal portion for inferonasal group and in the inferotemporal portion for inferotemporal group. CONCLUSIONS: The quadrant where the thinnest quadrant existed had the thinnest corneal thickness in comparing with any other quadrant.
Cornea

Degenerations and dystrophies of the cornea may generally be considered in four categories as follows; 1. Senile changes. 2. Degenerations. 3. Dystrqphies. 4. Corneal infiltrations due to metabolic disturbances, (carbohydrate, lipid, protein). In this discussion, many degenerations and dystrophies were reviewed.
Cornea*

In order to clarify the initiation and extent of the recovery of sensitivity in the grafted eyes, the corneal sensitivity was measured on 24 normal eyes and 12 grafted eyes with Cochet-Bonnet aesthesiometer. The sensitivity in the central cornea of the normal eyes was 59 +/- 4mm. The grafted eyes showed a significant difference of sensitivity in the different portion of the recipient peripheral cornea. In the corneal graft, some recovery of sensitivity was observed from the first post-operative month and reached 20 +/- 16mm after after 3-month. The sensitivity in the corneal graft was, however, still much lower than the normal eyes and also than the unsevered peripheral cornea. The sensitivity of the corneal graft showed no significant correlation with the age of graft and with the sensitivity of the recipient peripheral cornea.
Cornea ; Transplants*

In 1978, a nonprogressive corneal dystrophy was seperated from other causes of congenital opacification on the basis of unique clinincal findings and characteristic electronmicroscopic findings. This disorder, termed congenital hereditary stromal dystrophy, appears to the result of disordered stromal fibrogenesis. Recently, the autors have experienced 4 members of a family with typical electronmicroscopic findings of congenital heaeditary stromal dystrophy of the cornea. In this report we describe the characteristic findings of congenital hereditary stromal dystrophy.
Cornea* ; Humans

In 24 pterygium patients, the corneal curvature was measured before and after surgical removal. The norizontal curvature increased more than 0.5 D in 66.7% of cases on the 2 to 3 weeks postoperatively. The vertical curvature, however, showed no marked tendency to changes, and only 25% of cases showed more than 0.5 D increase on the 2 to 3 weeks postoperatively. As the pterygium invades the cornea extensively, the horizontal corneal curvature increased more markedly.
Cornea ; Humans ; Pterygium*

Granular corneal dystrophy is primary heredofamilial dystrophy of the cornea, which is characterized by the presence of plemorphic milk-white spots in the superficial stroma in the central cornea. This corneal dystrophy was first ,described by Arthur Groenouw in 1890. Since then. many other types of familial corneal dystrophies have been discribed by morphological characteristics. In 1938 BUcklers classified the corneal dystrophy into 3 types; granular, macular and lattice dystrophy, whose nemenclature is now generally accepted. Now we report 2 cases of granular corneal dystrophies which involved 2 sisters in a family.
Cornea ; Humans ; Siblings

The eye tumors are divided into intraocular and extraocular, and mainly involve lids, conjunctiva, cornea, and orbit. The authors analysed histopathological and clinical review of 9 cases of eye tumors that had experienced.
Conjunctiva ; Cornea ; Orbit

We performed eight radial line cuts in anterior radial keratotomy(RK) employing the Russian style and the American style incisions on 103 eyes from August/ 1989 to March/ 1990. To analyze the results of myopic correction according to the size of the central optical zone and the incision length in RK, we chose the central optical zone size according to the degree of myopia (4.0 mm from -1.50D to -2.75D, 3.5mm from -30D to -3.75D and 3.0mm above -4.0D) and measured the length of each of the eight radial incisions of the cornea. The results were as follows: 1. In determining the average length of each corneal incision in RK, the longest was the superior and superior-nasal incision and the shortest was the temporal and inferior-temporal incision, regardless of the central optical zone size. 2. The total length of each of the eight incisions in each eye ranged from the longest at 3.0mm of central optical zone and the shortest at 4.0mm of central optical zone Undoubtedly, total incision length affected clinical results not significantly (p>0.05). 3. Assessing the clinical effect of myopic correction according to the optical zone size, smaller diameter clear zones produce a greater flattening of the cornea than larger ones. 4. The clinical result was not significantly affected by the direction of the incision (p>0.05).
Cornea ; Keratotomy, Radial* ; Myopia

PURPOSE: To verify the intra-examiner and inter-examiner repeatability of corneal parameters obtained by GALILEI(TM). METHODS: Corneal parameters were measured by GALILEI in 44 eyes of 28 healthy subjects. One examiner took the measurements twice and intra-examiner repeatability was evaluated. Another examiner measured the corneal parameters once again and inter-examiner repeatability was evaluated. RESULTS: Intra-examiner and inter-examiner repeatability were high for corneal parameters including average SimK, flat SimK, steep SimK, average posterior corneal keratometry, flat posterior corneal keratometry, steep posterior corneal keratometry, central corneal thickness, total corneal volume, and average pupil diameter but low for limbus-to-limbus diameter (nasal-temporal and superior-inferior). CONCLUSIONS: Anterior and posterior corneal parameters of GALILEI showed good intra-examiner and inter-examiner repeatability. However, limbus-to-limbus diameter showed poor intra-examiner and inter-examiner repeatability. GALILEI can be useful in clinical applications with special consideration when measuring the limbus-to-limbus diameter.
Cornea ; Eye ; Pupil

Chondroitin sulfate (CS) in corneal preservation medium can porolong corneal preservation time. The solutions used in the experimental chambers were made of TC-199 (GIB Co.) either by itself of by adding 1% CS (Sigma) to the TC-199. The evaliation of the viability of corneas can be made by monitoring their physiological parameter. Thus, we monitored the transendothelial electrical potential difference (p.d.) across deepithelialized rabbit corneas. We found that TC-199 containing 1% CS maintained higher p.d.'s than the same solution without CS.
Chondroitin Sulfates* ; Chondroitin* ; Cornea*