Background: In 2005, a report showed that the mortality of fetal malformations accounts for 12.9% causes of death in newborns. It is importance for obstetricians and society as a whole to detect prenatal fetal malformations. Objective: To define various factors that might influence malformations in newborns. Subjects and method: A comparison study performed on 926 pregnant women with fetal malformations and 1852 pregnant women without fetal malformations amongst 20,345 pregnant women screened by prenatal ultrasound at the Central Hospital of Obstetrics and Gynecology, from July 2003 to July 2006. Results and conclusions: In comparing to 1826 pregnant women without fetal malformations, the fetal malformations were more frequently in young or older mothers (19 years old or less and 40 years old or over), farmers, the mother had been suffering from fever in the first three months of pregnancy; parents exposed to chemicals and pesticides. Mother\u2019s that previously had children with congenital malformation affected significantly the fetal malformation.
Fetal malformation ; congenital malformation ; pregnancy

No abstract available.
Cystic Adenomatoid Malformation of Lung, Congenital*

Objective: A retrospective study of the demographic, clinical and diagnostic profile, intervention and outcomes of children with Congenital Pulmonary Airway Malformation (CPAM) in Philippine Children’s Medical Center (PCMC) from January 2011 to December 2021 was presented. Methodology: Medical charts of identified patients were reviewed. Data obtained included demographic profile, clinical history, diagnostic procedures, intervention, and outcomes. The findings were analyzed and correlated with the synthesized findings from relevant studies about CPAM. Results: Twenty-three cases (n=23) were included in the study. Most of the patients were diagnosed at 1 to 11 months of age, accounting for 43.48% while there is a minimal disparity in terms of gender distribution. Seventy-five percent of neonates presented with respiratory distress while recurrent pneumonia occurred more frequently beyond the neonatal period. Four patients at 17.39% had incidental findings of CPAM on prenatal ultrasound. All cases were confirmed using a Chest CT scan and only six patients at 26.09% had Chest X-ray results consistent with CPAM. Eight cases were confirmed using biopsy wherein results were mainly Type I seen in 87.5% of cases. Lobectomy is the procedure of choice with 92.86% success rate. Overall, patients who underwent surgical intervention had a low complication rate at 6.25%. Conclusion CPAM is most common in patients aged 1 to 11 months and has no gender predilection. Neonates often present with respiratory distress while recurrent pneumonia is the most common clinical manifestation beyond neonatal period. CPAM can be detected using ultrasound prenatally and CT scan can confirm CPAM postnatally. Surgical intervention particularly lobectomy is the preferred option over conservative management which showed a favorable outcome. CPAM has an overall good prognosis. Findings of this research may guide clinicians in the diagnosis and management of CPAM in the Philippines.
Cystic Adenomatoid Malformation of Lung, Congenital

No abstract available.
Cystic Adenomatoid Malformation of Lung, Congenital* ; Diagnosis*

No abstract available.
Cystic Adenomatoid Malformation of Lung, Congenital* ; Lung*

No abstract available.
Cystic Adenomatoid Malformation of Lung, Congenital* ; Lung*

No abstract available.
Adult* ; Cystic Adenomatoid Malformation of Lung, Congenital* ; Humans

No abstract available.
Ascites* ; Cystic Adenomatoid Malformation of Lung, Congenital*

No abstract available.
Cystic Adenomatoid Malformation of Lung, Congenital* ; Lung*

Congenital cystic adenomatoid malformation (CCAM) is a rare developmental entity. Symptomatic patients must undergo thoracic surgery for lobectomy. Perioperative anesthetic management is challenging because it involves
thoracotomy in a young patient that may lead to hemodynamic compromise and inadequate ventilation. We present 3 cases of pediatric patients (6 months - 2 years old) with CCAM who underwent lobectomy.